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CNQX disodium

Catalog No. T8458 CAS 479347-85-8

CNQX disodium is a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures.

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CNQX disodium, CAS 479347-85-8

Pack Size	Availability	Price/USD
5 mg	In stock	$ 39.00
10 mg	In stock	$ 55.00
25 mg	In stock	$ 122.00
50 mg	In stock	$ 197.00
100 mg	In stock	$ 313.00
200 mg	In stock	$ 463.00
500 mg	In stock	$ 753.00
1 mL * 10 mM (in DMSO)	In stock	$ 43.00

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Purity: 98.46%

Biological Description

Chemical Properties

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Description	CNQX disodium is a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures.
Targets&IC50	Kainate receptor:1.5 μM (IC50), AMPA:0.3 μM (IC50)
In vivo	The ED50 for ?CNQX was 45.9+/-4.65 microg, respectively.?Intrathecal injection of a combination of CNQX and gabapentin produced a strong synergistic antiallodynic effect in neuropathic rats[1].

Molecular Weight	276.12
Formula	C9H2N4Na2O4
CAS No.	479347-85-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 25 mg/mL (90.54 mM)

References and Literature

1. S, R, Chen,et al. Synergistic effect between intrathecal non-NMDA antagonist and gabapentin on allodynia induced by spinal nerve ligation in rats.[J]. Anesthesiology, 2000.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Anti-Neurodegenerative Disease Compound Library Membrane Protein-targeted Compound Library Ion Channel Inhibitor Library Neuronal Signaling Compound Library NO PAINS Compound Library Anti-Cancer Compound Library Bioactive Compounds Library Max Bioactive Compound Library Anti-Alzheimer's Disease Compound Library

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AMPA receptor antagonist-2 BDZ-g AMPA receptor modulator-5 D-Cycloserine Mibampator Dizocilpine YM90K Sunifiram

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Keywords

CNQX disodium 479347-85-8 Membrane transporter/Ion channel Neuroscience iGluR Ionotropic glutamate receptors inhibit Inhibitor startle non-NMDA fear-potentiated kainate AMPA FG9065 disodium CNQX inhibitor

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