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Tylosin

Catalog No. T1003   CAS 1401-69-0
Synonyms: Fradizine, Tylosin A, Tylosine, Tylocine

Tylosin (Tylosine) is a macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.

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Tylosin Chemical Structure
Tylosin, CAS 1401-69-0
Pack Size Availability Price/USD Quantity
25 mg In stock $ 46.00
50 mg In stock $ 59.00
100 mg In stock $ 72.00
500 mg In stock $ 176.00
1 mL * 10 mM (in DMSO) In stock $ 30.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Tylosin (Tylosine) is a macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.
In vivo A 25 microliter volume of a 1-% L-epinephrine borate solution applied on the cornea of one eye in 12 monkeys reduces blood flow through the iris and the ciliary body by 59% and 20%, respectively, compared to the untreated control eyes[1]. Epinephrine is a direct-acting sympathomimetic α-adrenergic and β-adrenergic agonist with cyclic adenosine monophosphate-mediated, complex, bidirectional pharmacologic effects on many target organs[2]. In young adult rats, endogenous release of epinephrine facilitates stable memory formation for temporally associated events. Epinephrine enhances memory in young adult rats, in part, by increasing blood glucose levels needed to modulate memory[3]. Epinephrine is the primary drug administered during cardiopulmonary resuscitation (CPR) to reverse cardiac arrest. Epinephrine increases arterial blood pressure and coronary perfusion during CPR via alpha-1-adrenoceptor agonist effects[4].
Synonyms Fradizine, Tylosin A, Tylosine, Tylocine
Molecular Weight 916.1
Formula C46H77NO17
CAS No. 1401-69-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 91 mg/mL(99.3 mM)

TargetMolReferences and Literature

1. Entorf M, et al. Tylosin susceptibility of staphylococci from bovine mastitis. Vet Microbiol. 2014 Jul 16;171(3-4):368-73. 2. Pilcher CM, et al. Impact of tylosin phosphate and distillers dried grains with solubles on energy and nutrient digestibility and flow through the gastrointestinal tract in growing pigs. J Anim Sci. 2013 Dec;91(12):5687-95.

Related compound libraries

This product is contained In the following compound libraries:
Microbial Natural Product Library Bioactive Compound Library Natural Product Library FDA-Approved Drug Library Anti-infective Natural Product Library Human Metabolite Library Bioactive Compounds Library Max Anti-Infection Compound Library Covalent Natural Product Library FDA-Approved & Pharmacopeia Drug Library

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Keywords

Tylosin 1401-69-0 Microbiology/Virology Antibacterial Antibiotic diseases Fradizine inhibit Tylosin A Inhibitor infections mycoplasma Bacterial respiratory mastitis veterinary atrophic Tylosine Tylocine poultry rhinitis dysentery inhibitor

 

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