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Search Results for " ly-5 "

Targets

27

Compounds

22

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T2344 LY 344864 LY344864 5-HT Receptor
LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.
T0450 Fluoxetine LY-110140 5-HT Receptor , Serotonin Transporter , MRP , Autophagy
Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant activity.
T16801 (RS)-(Tetrazol-5-yl)glycine LY 285265,D,L-(tetrazol-5-yl)glycine NMDAR , iGluR
(RS)-(Tetrazol-5-yl)glycine (LY 285265) (D,L-(tetrazol-5-yl)glycine) is an effective and selective N-methyl-D-aspartate receptor agonist. (RS)-(Tetrazol-5-yl)glycine has EC50s of 99 nM, 1.7 μM for GluN1/GluN2D, and GluN1...
T4266 LY334370 LY 334370 5-HT Receptor
LY334370 is a selective 5-HT1F receptor agonist with a Ki of 1.6 nM
T1567 Olanzapine LY170053 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR
Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.
T1471 Duloxetine hydrochloride Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC and i...
T24423 LY5 LY 5,LY-5
LY5 is an inhibitor of STAT3 that acts by inhibiting cell viability, cell migration, and angiogenesis in medulloblastoma cells.
T9078 LY3405105 1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester CDK
LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester) is a novel CDK7 inhibitors.
T4310 Prexasertib LY2606368 Apoptosis , Chk
Prexasertib (LY2606368) is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity.
T22948 LY 272015 hydrochloride Others
LY 272015 hydrochloride is a 5-HT2B receptor antagonist.
T2344L LY 344864 racemate 5-HT Receptor
LY 344864 racemate is a 5-HT1F receptor agonist.
T24421 LY-2624803 DB-7,LY2624803,HY-10275,LY 2624803 5-HT Receptor , Histamine Receptor
LY-2624803 is a 5-HT2A receptor antagonist and histamine receptor inverse agonist that can be used to improve slow wave sleep.
T22947 LY266097 hydrochloride LY 266097 hydrochloride 5-HT Receptor
LY266097 hydrochloride (LY 266097 hydrochloride) is an antagonist of 5-HT2 with pKis of 7.7, 9.8, and 7.6 for human 5-HT2A, 5-HT2B, and 5-HT2C and can be used in studies about depression.
T27918 LY 43578 LY-43578,LY43578 P450 , Aromatase
LY 43578 is an orally active aromatase inhibitor. LY43578 could inhibit O-demethylation of P-450-dependent p-nitroanisole and N-demethylation of ethylmorphine (IC50 of 0.3 and 5 μm, respectively) in rat liver microsomes....
T16977 Talampanel GYKI-53773,LY-300164 Apoptosis , GluR
Talampanel (LY-300164) is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor antagonist with anti-seizure activity. Talampanel (IVAX) has neuroprotective effects in rodent stroke models.
T27894 LY 206130 LY206130,LY-206130
LY 206130 is an antagonist of serotonin 5-HT1A.
T27910 LY 278584 LY278584,LY-278584
LY 278584 is an antagonist of 5-HT3-receptor.
T27955 LY-426965 LY 426965
LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.
T15825 LY 178002 Retinoid Receptor
LY 178002 is an effective inhibitor of 5-lipoxygenase (5-LPO), phospholipase A2 (IC50: 0.6 μM for 5-lipoxygenase). LY 178002 also inhibits cellular production of LTB4 by human polymorphonuclear leukocytes and displays re...
T71374 LY 178210
LY 178210 is a 5-hydroxytryptamine receptor agonist.
T27921 LY 53857 LY-53857,LY53857
LY 53857 is a potent and selective antagonist of 5-HT2 serotonin receptor.
T27879 LY 165163 LY-165,163,LY165,163,LY 165,163
LY-165163 is a selective antagonists of 5-HT1A and 5-HT1D serotonin receptor.
T11902 LY 344864 S-enantiomer Others
LY 344864 S-enantiomer, the S-enantiomer of LY344864, serves as a 5-HT1F receptor agonist.
T27914 LY 293284 LY293284,LY-293284
LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.
T27915 LY 302148 LY-302148,LY302148
LY 302148 , a 5-HT1F receptor agonist, inhibits neurogenic dural inflammation in guinea pigs. It has potential for migraine therapeutics.
T27878 LY 164929 LY-164929,LY164929
LY 164929 is a highly selective ligand for the lower affinity [3H]D-Ala2-D-Leu-5-enkephalin binding site.
T41295 LY 344864 hydrochloride
LY 344864 hydrochloride is a selective receptor agonist with an affinity of 6 nM (Ki) at the 5-HT1F receptor.

Compounds

LY 344864
T2344
Synonym: LY344864
Target: 5-HT Receptor
Fluoxetine
T0450
Synonym: LY-110140
Target: 5-HT Receptor, Serotonin Transporter, MRP, Autophagy
(RS)-(Tetrazol-5-yl)glycine
T16801
Synonym: LY 285265,D,L-(tetrazol-5-yl)glycine
Target: NMDAR, iGluR
LY334370
T4266
Synonym: LY 334370
Target: 5-HT Receptor
Olanzapine
T1567
Synonym: LY170053
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR
Duloxetine hydrochloride
T1471
Synonym: Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine
LY5
T24423
Synonym: LY 5,LY-5
Target:
LY3405105
T9078
Synonym: 1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester
Target: CDK
Prexasertib
T4310
Synonym: LY2606368
Target: Apoptosis, Chk
LY 272015 hydrochloride
T22948
Synonym:
Target: Others
LY 344864 racemate
T2344L
Synonym:
Target: 5-HT Receptor
LY-2624803
T24421
Synonym: DB-7,LY2624803,HY-10275,LY 2624803
Target: 5-HT Receptor, Histamine Receptor
LY266097 hydrochloride
T22947
Synonym: LY 266097 hydrochloride
Target: 5-HT Receptor
LY 43578
T27918
Synonym: LY-43578,LY43578
Target: P450, Aromatase
Talampanel
T16977
Synonym: GYKI-53773,LY-300164
Target: Apoptosis, GluR
LY 206130
T27894
Synonym: LY206130,LY-206130
Target:
LY 278584
T27910
Synonym: LY278584,LY-278584
Target:
LY-426965
T27955
Synonym: LY 426965
Target:
LY 178002
T15825
Synonym:
Target: Retinoid Receptor
LY 178210
T71374
Synonym:
Target:
LY 53857
T27921
Synonym: LY-53857,LY53857
Target:
LY 165163
T27879
Synonym: LY-165,163,LY165,163,LY 165,163
Target:
LY 344864 S-enantiomer
T11902
Synonym:
Target: Others
LY 293284
T27914
Synonym: LY293284,LY-293284
Target:
LY 302148
T27915
Synonym: LY-302148,LY302148
Target:
LY 164929
T27878
Synonym: LY-164929,LY164929
Target:
LY 344864 hydrochloride
T41295
Synonym:
Target:

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-05308 CD45 Protein, Human, Recombinant (aa 1-529, His) Human HEK293 Cells
CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPY-05748 CD45 Protein, Human, Recombinant (aa 26-577, His) Human HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3.
TMPJ-00455 SLAMF5 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
CD84, also called SLAMF5, is a member of the CD2 subgroup of the immunoglobulin receptor superfamily. Members of this CD2 subgroup mediate signal transduction through the interaction of its immunoreceptor tyrosine-based ...
TMPY-04277 CD45 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
CD45 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.7 kDa and the accession number is P06800-6.
TMPY-03270 CD45 Protein, Mouse, Recombinant (aa 453-1152, His & GST) Mouse Baculovirus Insect Cells
CD45 Protein, Mouse, Recombinant (aa 453-1152, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 108.2 kDa and the accession number is AAA39458.1.
TMPY-03468 CD45 Protein, Mouse, Recombinant (aa 453-1152) Mouse Baculovirus Insect Cells
CD45 Protein, Mouse, Recombinant (aa 453-1152) is expressed in Baculovirus insect cells. The predicted molecular weight is 81 kDa and the accession number is AAA39458.1.
TMPK-00183 CD20 Protein, Human, Recombinant (His & Avi) Human E. coli
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until matur...
TMPK-00423 CD45 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPK-00424 CD45 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPK-00447 CD45 Protein, Human, Recombinant (aa 26-577, hFc) Human HEK293 Cells
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPY-00711 CD45 Protein, Human, Recombinant (hFc) Human HEK293 Cells
CD45 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.1 kDa and the accession number is P08575-4.
TMPJ-00794 CD45 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
CD45 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 120-160 KDa and the accession number is P06800.
TMPJ-00410 CD45R0 Protein, Human, Recombinant (His) Human HEK293 Cells
CD45R0 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 80-120 KDa and the accession number is P08575-4.
TMPJ-00808 CD45RA Protein, Human, Recombinant (His) Human HEK293 Cells
CD45RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-135 KDa and the accession number is P08575-8.
TMPY-02440 SAP/SH2D1A Protein, Human, Recombinant (His) Human E. coli
SH2domain-containing protein 1A (SH2D1A / SAP) is a 128 amino acid protein, containing a single Src homology 2 (SH2) domain, flanked by 5 amino acids at the N-terminus and 25 amino acids at the C-terminus. The absence of...
TMPJ-00854 ETS1 Protein, Human, Recombinant (His) Human E. coli
ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or ...
TMPY-05387 SLAMF7 Protein, Human, Recombinant (hFc) Human HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-05498 SR-BI/SCARB1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5.
TMPY-05547 SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated Human HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-04318 GRIK2 Protein, Human, Recombinant (hFc) Human HEK293 Cells
GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar...
TMPK-01363 SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
TMPK-01357 SIRP alpha V5 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
CD45 Protein, Human, Recombinant (aa 1-529, His)
TMPY-05308
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His)
TMPY-05748
Species: Human
Expression System: HEK293 Cells
SLAMF5 Protein, Mouse, Recombinant (His)
TMPJ-00455
Species: Mouse
Expression System: HEK293 Cells
CD45 Protein, Mouse, Recombinant (hFc)
TMPY-04277
Species: Mouse
Expression System: HEK293 Cells
CD45 Protein, Mouse, Recombinant (aa 453-1152, His & GST)
TMPY-03270
Species: Mouse
Expression System: Baculovirus Insect Cells
CD45 Protein, Mouse, Recombinant (aa 453-1152)
TMPY-03468
Species: Mouse
Expression System: Baculovirus Insect Cells
CD20 Protein, Human, Recombinant (His & Avi)
TMPK-00183
Species: Human
Expression System: E. coli
CD45 Protein, Human, Recombinant (His & Avi)
TMPK-00423
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00424
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, hFc)
TMPK-00447
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (hFc)
TMPY-00711
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Mouse, Recombinant (His)
TMPJ-00794
Species: Mouse
Expression System: HEK293 Cells
CD45R0 Protein, Human, Recombinant (His)
TMPJ-00410
Species: Human
Expression System: HEK293 Cells
CD45RA Protein, Human, Recombinant (His)
TMPJ-00808
Species: Human
Expression System: HEK293 Cells
SAP/SH2D1A Protein, Human, Recombinant (His)
TMPY-02440
Species: Human
Expression System: E. coli
ETS1 Protein, Human, Recombinant (His)
TMPJ-00854
Species: Human
Expression System: E. coli
SLAMF7 Protein, Human, Recombinant (hFc)
TMPY-05387
Species: Human
Expression System: HEK293 Cells
SR-BI/SCARB1 Protein, Human, Recombinant (hFc)
TMPY-05498
Species: Human
Expression System: HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated
TMPY-05547
Species: Human
Expression System: HEK293 Cells
GRIK2 Protein, Human, Recombinant (hFc)
TMPY-04318
Species: Human
Expression System: HEK293 Cells
SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-01363
Species: Human
Expression System: HEK293 Cells
SIRP alpha V5 Protein, Human, Recombinant (His & Avi)
TMPK-01357
Species: Human
Expression System: HEK293 Cells
TargetMol