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Duloxetine hydrochloride

Catalog No. T1471 CAS 136434-34-9

Synonyms: LY-248686 hydrochloride, (S)-Duloxetine hydrochloride, Duloxetine HCl, LY-248686 HCl

Duloxetine hydrochloride is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC and is also used for the treatment of pain in patients with DIABETES MELLITUS and FIBROMYALGIA.

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Duloxetine hydrochloride, CAS 136434-34-9

Pack Size	Availability	Price/USD
10 mg	In stock	54.00
50 mg	In stock	81.00
100 mg	In stock	108.00
200 mg	In stock	135.00
1 mL * 10 mM (in DMSO)	In stock	50.00

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Purity 99.97%

HNMR HPLC COA

Purity 100.00%

HNMR LCMS COA

Datasheet SDS

Biological Description

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Storage & Solubility Information

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Description	Duloxetine hydrochloride is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC and is also used for the treatment of pain in patients with DIABETES MELLITUS and FIBROMYALGIA.
Targets&IC50	DA transporter , Noradrenaline transporter (Sodium-dependent) , Sert (Sodium-dependent)

Synonyms	LY-248686 hydrochloride , (S)-Duloxetine hydrochloride , Duloxetine HCl , LY-248686 HCl
Purity	99.97%
Molecular Weight	333.88
Formula	C18H20ClNOS
CAS No.	136434-34-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 6 months

Solubility Information

DMSO: 67 mg/mL (200.67 mM)

Ethanol: <1 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Solution 1

2% DMSO+30% PEG 300+ddWater: 20mg/mL

Citations

References and Literature

1. Chen F, et al. Eur Neuropsychopharmacol. 2005 Mar; 15(2):193-8.

Related compound libraries

This product is contained In the following compound libraries：

Approved Drug Library Bioactive Compound Library Inhibitor Library Anti-Cancer Compound Library Clinical Compound Library Anti-Diabetic Compound Library Neuronal Signaling Compound Library FDA-Approved Drug Library GPCR Compound Library Anti-Cardiovascular Disease Compound Library Anti-Obesity Compound Library Drug Repurposing Compound Library Neurotransmitter Receptor Compound Library Anti-Neurodegenerative Disease Compound Library Drug-induced Liver Injury (DILI) Compound Library NMPA-Approved Drug Library FDA-Approved & Pharmacopeia Drug Library Anti-Parkinson's Disease Compound Library Anti-Alzheimer's Disease Compound Library

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Related compounds with same targets

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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