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Olanzapine

Catalog No. T1567   CAS 132539-06-1
Synonyms: LY170053

Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.

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Olanzapine Chemical Structure
Olanzapine, CAS 132539-06-1
Pack Size Availability Price/USD Quantity
25 mg In stock $ 30.00
50 mg In stock $ 39.00
100 mg In stock $ 55.00
200 mg In stock $ 80.00
500 mg In stock $ 133.00
1 mL * 10 mM (in DMSO) In stock $ 43.00
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Purity: 100%
Purity: 99.92%
Purity: 99.86%
Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.
Synonyms LY170053
Molecular Weight 312.43
Formula C17H20N4S
CAS No. 132539-06-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

1eq. HCl: 31.2 mg/mL (100 mM)

DMSO: 31.2 mg/mL (100 mM)

TargetMolReferences and Literature

1. Bymaster FP, et al. J Clin Psychiatry, 1997, 58, 28-36. 2. Zhang W, et al. Neuropsychopharmacology, 2000, 23(3), 250-262. 3. Li XM, et al. Psychopharmacology (Berl), 1998, 136(2), 153-161. 4. Dorph-Petersen KA, et al. Neuropsychopharmacology, 2005, 30(9), 1649-1661. 5. Ader M, et al. Diabetes, 2005, 54(3), 862-871.

TargetMolCitations

1. Partyka A, Górecka K, Gdula-Argasińska J, et al.Selective 5-HT6 Receptor Ligands (Agonist and Antagonist) Show Different Effects on Antipsychotic Drug-Induced Metabolic Dysfunctions in Rats.Pharmaceuticals.2023, 16(2): 154.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Drug Library Anti-Cancer Approved Drug Library Anti-Cancer Clinical Compound Library Anti-Neurodegenerative Disease Compound Library Anti-Alzheimer's Disease Compound Library Human Metabolite Library FDA-Approved & Pharmacopeia Drug Library Endocrinology-Hormone Compound Library Anti-Aging Compound Library Anti-Lung Cancer Compound Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Olanzapine 132539-06-1 GPCR/G Protein Neuroscience 5-HT Receptor Dopamine Receptor Adrenergic Receptor AChR Inhibitor Beta Receptor cell Apoptosis Muscarinic acetylcholine receptor mAChR damage Mitophagy inhibit antipsychotic Serotonin Receptor neuronal anticholinergic 5-hydroxytryptamine Receptor Autophagy LY-170053 Mitochondrial Autophagy LY170053 5-HT2 mitochondrial SH-SY5Y LY 170053 inhibitor

 

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