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Search Results for " emb "

Targets

35

Compounds

20

Natural Products

9

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
TP1286 Carcinoembryonic Antigen CEA Others
Carcinoembryonic antigen (CEA) is a protein that is present in certain tissues of a developing baby (fetus)
T2711 Chembridge-5861528 TCS 5861528 TRP/TRPV Channel
Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM, respectively.
T60093 CHEMBL1380345 N,N'-(Ethane-1,2-diyl)bis(3-methylbenzenesulfonamide) Antibacterial
CHEMBL1380345 exhibits antibacterial activity against Staphylococcus aureus, Bacillus cereus, and Escherichia coli with pMIC values of 3.64, 3.56, and 3.70, respectively.
T74178 Glembatumumab vedotin CR011-vcMMAE,CR 011 ADC,CDX-011 Microtubule Associated
Glembatumumab vedotin (CDX-011) is an antibody-activated small molecule coupling, Glembatumumab vedotin has potent anticancer effects and can be used in the study of triple negative breast cancer (TNBC).
T3071 Olverembatinib GZD 824 Bcr-Abl
Olverembatinib (GZD 824) is an orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT, IC50: 0.34 nM) and Bcr-Abl(T315I, IC50: 0.68 nM).
T27112 Cytembena DNA/RNA Synthesis
Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.
T28750 Sembragiline RG-1577,EVT-302,RO-4602522,RO4602522,RG1577,EVT302 MAO
Sembragiline (EVT-302) is a selective MAO-B inhibitor for the study of Alzheimer's disease (AD).
T8598 CHEMBL241987 2-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE Adenosine Receptor
CHEMBL241987 targets the Adenosine receptor A3 (human)
T2429 Olverembatinib dimesylate GZD824 Dimesylate,HQP1351 Bcr-Abl
Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).
T67988 Embeconazole R 120758,CS 758 Antifungal
Embeconazole (R 120758) is a triazole antifungal agent.Embeconazole has strong in vitro activity against clinically important fungi such as Candida, Aspergillus and Cryptococcus neoformans.
T9908 Pembrolizumab PD-1/PD-L1
Pembrolizumab is a humanized monoclonal antibody inhibiting the PD-1 receptor and the first in the class of agents called the HER2 dimerization inhibitors that impairs the ability of HER2 to bind to other members of the ...
T77439 Glembatumumab Others
Glembatumumab is a fully human IgG2 monoclonal antibody targeting the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma.Glembatumumab is a naked antibody to Glembatumumab vedotin and ...
T60092 CHEMBL1276927 N-[3-(1H-benzimidazol-2-yl)phenyl]-3-methylbenzamide,N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide Antibacterial , Parasite
CHEMBL1276927 (N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide) shows antibacterial and antiparasitic activities against Chlamydia pneumoniae and Leishmania donovani.
TP2417 Tidembersat Others
Tidembersat is a small molecule compound used to treat and/or prevent degenerative diseases such as Huntington's chorea, schizophrenia, neurological.
T124967 D7-Mesembrenone
D7-Mesembrenone is a useful organic compound for research related to life sciences. The catalog number is T124967 and the CAS number is 35714-44-4.
T124052 Calophymembranside B
Calophymembranside B is a useful organic compound for research related to life sciences. The catalog number is T124052 and the CAS number is 869285-60-9.
T31373 Dembrexine HCl Dembroxol
Dembrexine is a bioactive agent.
T70261 Amitriptyline Embonate
Amitriptyline Embonate is an inhibitor of the re-uptake of norepinephrine and serotonin, thereby inhibiting N-methyl-D-aspartate (NMDA) receptors.
TP2198 Platelet Membrane Glycoprotein IIB Peptide (296-306) Others
GPllb is composed of a 125 Kd heavy chain that is disulfide-linked to a 23 Kd light chain. Hydropathicity analysis of the cDNA sequence indicates that GPllb is anchored to the platelet through a single transmembrane doma...
T81824 Membrane-Permeable Sequence, MPS
Membrane-Permeable Sequence (MPS) is a cell-penetrating peptide (CPP) utilized in the investigation of membrane crossing mechanisms [1].
T80209 Human membrane-bound PD-L1 polypeptide PD-1/PD-L1
Human membrane-bound PD-L1 polypeptide serves as an antigen for inducing the production of PD-L1 antibodies [1].
T71902 CHEMBL94431
CHEMBL94431 is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase.
T11180 Embramine Others
Embramine, used as an antihistamine and anticholinergic, is a monoethanolamine.
T131462 Embelin Dimethyl ether
Embelin Dimethyl ether is a useful organic compound for research related to life sciences and the catalog number is T131462.
T70054 Novembichin
Novembichin is a nitrogen mustard agent that crosslinks with DNA, causing inhibition of DNA synthesis.
T69405 Metformin embonate
Metformin embonate is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose.
T131083 Cembratetraene-16,2:19,6-diolide
Cembratetraene-16,2:19,6-diolide is a useful organic compound for research related to life sciences and the catalog number is T131083.
T35434 β-Cembrenediol
β-Cembrenediol (β-CBT) is a natural product from tobacco plants that is found in cigarette smoke condensate. β-CBT inhibits induction of the early antigen of Epstein-Barr virus (EA-EBV) by 12-O-tetradecanoylphorbol-13-ac...
T82476 Embramine hydrochloride
Embramine hydrochloride is a monoethanolamine derivative utilized for its antihistaminic and anticholinergic properties [1].
T68384 SCHEMBL12616233
SCHEMBL12616233 is a novel inhibitor of SARS-CoV-2 main protease (MPro).
T31619 Embusartan UNII-4MY73645XA,Bay 10-6734
Embusartan (BAY 10-6734) is a potent, orally active angiotensin II receptor antagonist used as an antihypertensive agent.
T124625 α-Cembrenediol
α-Cembrenediol is a useful organic compound for research related to life sciences and the catalog number is T124625.
T28749 SEMBL
SEMBL, a novel inhibitor of DNA binding of NF-kappaB component p65 in vitro, inhibits NF-kappaB and cellular invasion in ovarian carcinoma ES-2 cells.
T76916 Bafisontamab
Bafisontamab (EMB-01) is a bispecific antibody that targets EGFR and cMET, displaying antitumor activity [1].
T37880 OPC-167832
OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-16...

Compounds

Carcinoembryonic Antigen CEA
TP1286
Synonym:
Target: Others
Chembridge-5861528
T2711
Synonym: TCS 5861528
Target: TRP/TRPV Channel
CHEMBL1380345
T60093
Synonym: N,N'-(Ethane-1,2-diyl)bis(3-methylbenzenesulfonamide)
Target: Antibacterial
Glembatumumab vedotin
T74178
Synonym: CR011-vcMMAE,CR 011 ADC,CDX-011
Target: Microtubule Associated
Olverembatinib
T3071
Synonym: GZD 824
Target: Bcr-Abl
Cytembena
T27112
Synonym:
Target: DNA/RNA Synthesis
Sembragiline
T28750
Synonym: RG-1577,EVT-302,RO-4602522,RO4602522,RG1577,EVT302
Target: MAO
CHEMBL241987
T8598
Synonym: 2-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE
Target: Adenosine Receptor
Olverembatinib dimesylate
T2429
Synonym: GZD824 Dimesylate,HQP1351
Target: Bcr-Abl
Embeconazole
T67988
Synonym: R 120758,CS 758
Target: Antifungal
Pembrolizumab
T9908
Synonym:
Target: PD-1/PD-L1
Glembatumumab
T77439
Synonym:
Target: Others
CHEMBL1276927
T60092
Synonym: N-[3-(1H-benzimidazol-2-yl)phenyl]-3-methylbenzamide,N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide
Target: Antibacterial, Parasite
Tidembersat
TP2417
Synonym:
Target: Others
D7-Mesembrenone
T124967
Synonym:
Target:
Calophymembranside B
T124052
Synonym:
Target:
Dembrexine HCl
T31373
Synonym: Dembroxol
Target:
Amitriptyline Embonate
T70261
Synonym:
Target:
Platelet Membrane Glycoprotein IIB Peptide (296-306)
TP2198
Synonym:
Target: Others
Membrane-Permeable Sequence, MPS
T81824
Synonym:
Target:
Human membrane-bound PD-L1 polypeptide
T80209
Synonym:
Target: PD-1/PD-L1
CHEMBL94431
T71902
Synonym:
Target:
Embramine
T11180
Synonym:
Target: Others
Embelin Dimethyl ether
T131462
Synonym:
Target:
Novembichin
T70054
Synonym:
Target:
Metformin embonate
T69405
Synonym:
Target:
Cembratetraene-16,2:19,6-diolide
T131083
Synonym:
Target:
β-Cembrenediol
T35434
Synonym:
Target:
Embramine hydrochloride
T82476
Synonym:
Target:
SCHEMBL12616233
T68384
Synonym:
Target:
Embusartan
T31619
Synonym: UNII-4MY73645XA,Bay 10-6734
Target:
α-Cembrenediol
T124625
Synonym:
Target:
SEMBL
T28749
Synonym:
Target:
Bafisontamab
T76916
Synonym:
Target:
OPC-167832
T37880
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T0810 Ethambutol dihydrochloride Ethambutol 2HCl,Emb dihydrochloride,CL40881 Antibacterial , Antibiotic , Antifungal
Ethambutol dihydrochloride (CL40881) is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.
T13514 5-MethoxyPinocembroside Others
5-MethoxyPinocembroside is a flavonoid isolated from leaves of Moringa oleifera.
T2992 Pinocembrin 5,7-Dihydroxyflavanone,Dihydrochrysin,Galangin flavanone NF-κB , Reactive Oxygen Species , Antibacterial , Autophagy
Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.
TN2078 Pinocembrin chalcone 2',4',6'-Trihydroxychalcone,Pinocembrinchalcone Calcium Channel , Tyrosinase , Antibacterial , Antifection
Pinocembrin chalcone is an inhibitor of tyrosinase with antimutagenic effects. Pinocembrin chalcone can be used in studies about the prevention of gastric ulcers.
T5710 Pinocembrin-7-O-β-D-glucopyranoside Pinocembrin 7-O-beta-D-glucoside Others
Pinocembrin-7-O-β-D-glucopyranoside (Pinocembrin 7-O-beta-D-glucoside) is a natual product isolated from Penthorum chinense Pursh.
TN2077 (+/-)-Pinocembrin NSC 43318,(±)-5,7-Dihydroxyflavanone GPR , Others
(+/-)-Pinocembrin (NSC-43318), a natural product from axillary pines, is a GPR120 ligand that promotes wound healing in the HaCaT cell line.
T2S1682 Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose,pinocembrin-7-o-3-o-galloyl-4-6-hexahydroxydiphenoyl-beta-d-glucoside Amylase
Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside can moderately inhibit α-amylase activity, with the IC50 value of 0.03 umol/ml.
TN4221 Homoembelin 2,5-dihydroxy-3-nonyl-1,4-benzoquinone Antibacterial
Homoembelin (2,5-dihydroxy-3-nonyl-1,4-benzoquinone) is a pigment from E. ribes and C. monocarpus that has antibacterial effects and can be used to study multidrug-resistant bacterial infections.
T6485 Embelin NSC 91874,Emberine,Embelic acid Apoptosis , NF-κB , Lipoxygenase , IAP , Prostaglandin Receptor , Autophagy
Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).
T28019 (-)-Mesembrine Mesembrin,Mesembrine,Mesembranone
Mesembrine is a serotonin reuptake inhibitor and is also a weak inhibitor of the enzyme phosphodiesterase 4 (PDE4).
TN6319 Embinin
Embinin is a natural product for research related to life sciences. The catalog number is TN6319 and the CAS number is 52589-13-6.
T73857 Mesembrine
Mesembrine ((+)-Mesembrine), a primary alkaloid distinguished by its aryloctahydroindole structure, acts as a potent 5-HT transporter inhibitor with an inhibition constant (K i) of 1.4 nM. Additionally, it demonstrates i...
T83379 2-Hydroxypinocembrin
2-Hydroxypinocembrin, a member of the 2-hydroxyflavanones, serves as a substrate for flavonoid C-glycosyltransferases [1].
T19772 Mesembrenone (+)-Mesembrenone
Mesembrenone is a selective the serotonin transporter (SERT) inhibitor. Mesembrenone is the main alkaloid of Sceletium tortuosum.
TN4792 Pinocembrin diacetate Others
Pinocembrin diacetate is a natural product for research related to life sciences. The catalog number is TN4792 and the CAS number is 111441-88-4.
T77289 5-O-Methylembelin
5-O-Methylembelin is a natural isocoumarin that inhibits PCSK9 , low-density lipoprotein receptor (IDOL) , and sterol regulatory element binding protein 2 (SREBP2) mRNA expression [1] .
T72742 (-)-Pinocembrin
(-)-Pinocembrin demonstrates anti-mycobacterial activity against Mycobacterium tuberculosis H37Ra, presenting IC 50 values of 1.11 mg/mL in the dormant phase and 1.21 mg/mL in the active phase. Additionally, this compoun...
TN4791 Pinocembrin 7-acetate Others
Pinocembrin 7-acetate has antitumor activity.
TN5509 (2S)-Pinocembrin 7-O-[2''-O-(5'''-O-trans-cinnamoyl)-β-D-apiofuranosyl]-β-D-glucoside (2S)-Pinocembrin 7-O-[cinnamoyl(1→5)-β-D-apiosyl(1→2)]-β-D-glucoside
(2S)-Pinocembrin 7-O-[2''-O-(5'''-O-trans-cinnamoyl)-β-D-apiofuranosyl]-β-D-glucoside is a natural product for research related to life sciences. The catalog number is TN5509 and the CAS number is 773899-29-9.
T72856 (+)-Cembrene A
(+)-Cembrene A, a nontoxic α-glucosidase inhibitor to human normal hepatocyte (LO2) cells, exhibits an IC50 value of 30.31 μM.

Natural Products

Ethambutol dihydrochloride
T0810
Synonym: Ethambutol 2HCl,Emb dihydrochloride,CL40881
Target: Antibacterial, Antibiotic, Antifungal
5-MethoxyPinocembroside
T13514
Synonym:
Target: Others
Pinocembrin
T2992
Synonym: 5,7-Dihydroxyflavanone,Dihydrochrysin,Galangin flavanone
Target: NF-κB, Reactive Oxygen Species, Antibacterial, Autophagy
Pinocembrin chalcone
TN2078
Synonym: 2',4',6'-Trihydroxychalcone,Pinocembrinchalcone
Target: Calcium Channel, Tyrosinase, Antibacterial, Antifection
Pinocembrin-7-O-β-D-glucopyranoside
T5710
Synonym: Pinocembrin 7-O-beta-D-glucoside
Target: Others
(+/-)-Pinocembrin
TN2077
Synonym: NSC 43318,(±)-5,7-Dihydroxyflavanone
Target: GPR, Others
Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside
T2S1682
Synonym: Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose,pinocembrin-7-o-3-o-galloyl-4-6-hexahydroxydiphenoyl-beta-d-glucoside
Target: Amylase
Homoembelin
TN4221
Synonym: 2,5-dihydroxy-3-nonyl-1,4-benzoquinone
Target: Antibacterial
Embelin
T6485
Synonym: NSC 91874,Emberine,Embelic acid
Target: Apoptosis, NF-κB, Lipoxygenase, IAP, Prostaglandin Receptor, Autophagy
(-)-Mesembrine
T28019
Synonym: Mesembrin,Mesembrine,Mesembranone
Target:
Embinin
TN6319
Synonym:
Target:
Mesembrine
T73857
Synonym:
Target:
2-Hydroxypinocembrin
T83379
Synonym:
Target:
Mesembrenone
T19772
Synonym: (+)-Mesembrenone
Target:
Pinocembrin diacetate
TN4792
Synonym:
Target: Others
5-O-Methylembelin
T77289
Synonym:
Target:
(-)-Pinocembrin
T72742
Synonym:
Target:
Pinocembrin 7-acetate
TN4791
Synonym:
Target: Others
(2S)-Pinocembrin 7-O-[2''-O-(5'''-O-trans-cinnamoyl)-β-D-apiofuranosyl]-β-D-glucoside
TN5509
Synonym: (2S)-Pinocembrin 7-O-[cinnamoyl(1→5)-β-D-apiosyl(1→2)]-β-D-glucoside
Target:
(+)-Cembrene A
T72856
Synonym:
Target:

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-02637 Embigin Protein, Mouse, Recombinant (His) Mouse in vitro E. coli expression system
Plays a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane. Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervat...
TMPH-00023 Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & Myc) Acinetobacter baumannii E. coli
Functions as a porin. Induces apoptosis in human cell lines through caspase-dependent and AIF-dependent pathways. Purified Omp38 enters host cell and localizes to the mitochondria, which presumably leads to a release of ...
TMPH-01138 Human coronavirus 229E Membrane protein (His) HCoV-229E E. coli
Human coronavirus 229E Membrane protein (His) is expressed in E. coli.
TMPH-00022 Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & SUMO) Acinetobacter baumannii E. coli
Porin. Induces apoptosis in human cells through caspases-dependent and AIF-dependent pathways. Purified Omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as...
TMPY-04904 Zika virus (ZIKV) (strain Zika SPH2015) M/Membrane protein (Fc) ZIKV HEK293
Zika virus (ZIKV) infection causes microcephaly and has been linked to other brain abnormalities. ZIKV has a more selective and larger impact on the expression of genes involved in DNA replication and repair. P53 inhibit...
TMPH-00021 Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His) Acinetobacter baumannii Yeast
Porin. Induces apoptosis in human cells through caspases-dependent and AIF-dependent pathways. Purified Omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as...
TMPH-01151 Human coronavirus NL63 Membrane protein (His) HCoV-NL63 in vitro E. coli expression system
Human coronavirus NL63 Membrane protein (His) is expressed in in vitro E. coli expression system.
TMPH-03640 34 kDa membrane antigen Protein, Treponema pallidum, Recombinant (His & Myc) Treponema pallidum E. coli
34 kDa membrane antigen Protein, Treponema pallidum, Recombinant (His & Myc) is expressed in E. coli.
TMPH-00018 29 kDa outer membrane Protein, Acinetobacter baumannii, Recombinant (His & Myc & SUMO) Acinetobacter baumannii E. coli
May be involved in transporting molecules across the outer membrane.
TargetMol