Store the unopened solution at -20℃, and store it at 4℃ after melting to avoid repeated freeze-thaw
Pembrolizumab is a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors impairs the ability of HER2 to bind to other members of the HER family.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | 542.00 |
Description | Pembrolizumab is a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors impairs the ability of HER2 to bind to other members of the HER family. |
Targets&IC50 | PD-1 |
Cell Research |
Objective: To examine the effect of high-dose steroid therapy on lymphocyte proliferation/functionality after stimulation with anti-CD3 in the presence of pembrolizumab
Concentrations: 5 μg/mL
Method: Isolated PBMCs were pre-treated with prednisone (1 nM - 1 mM) before anti-CD3 stimulation. Anti-CD3-stimulated cells were then incubated with pembrolizumab and their proliferative capacity and IL-2 secretion ability were measured by carboxyfluorescein succinimidyl ester (CFSE) staining and ELISA.
Cell lines: Human PBMCs
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Animal Research |
Objective: To evaluate the pharmacokinetics and biodistribution of 89Zr-labeled Pembrolizumab
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Synonyms | Pembrolizumab (anti-PD-1) , anti-PD-1 , MK-3475 , lambrolizumab |
Purity | 98.1% |
Molecular Weight | 149000 |
CAS No. | 1374853-91-4 |
Store the unopened solution at -20℃, and store it at 4℃ after melting to avoid repeated freeze-thaw
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.