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Ethambutol dihydrochloride

Name: Ethambutol dihydrochloride
Brand: TargetMol
SKU: T0810
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0810Cas No. 1070-11-7

Alias Ethambutol 2HCl, Emb dihydrochloride, CL40881

Ethambutol dihydrochloride is an anti-mycobacterial compound that inhibits arabinosyl transferase activity to prevent cell wall formation and can be used to induce hyperuricemia models.

Ethambutol dihydrochloride

🥰Excellent

Purity: 99.95%

Catalog No. T0810Alias Ethambutol 2HCl, Emb dihydrochloride, CL40881Cas No. 1070-11-7

Ethambutol dihydrochloride is an anti-mycobacterial compound that inhibits arabinosyl transferase activity to prevent cell wall formation and can be used to induce hyperuricemia models.

Pack Size	Price	Availability
500 mg	$29	In Stock
1 g	$42	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock

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Batch Information

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Purity:99.95%

Resource Download

COA HNMR LCMS HPLC

Product Introduction

Bioactivity

Description	Ethambutol dihydrochloride is an anti-mycobacterial compound that inhibits arabinosyl transferase activity to prevent cell wall formation and can be used to induce hyperuricemia models.
In vitro	In animal models, Ethambutol is administered orally at a dosage of 100 mg/kg.
In vivo	Ethambutol primarily targets the product of the embB gene, inducing mutations within the emb gene in drug-resistant strains of tuberculosis. In Mycobacterium smegmatis, Ethambutol affects arabinogalactan and lipoarabinomannan biosynthesis.
Synonyms	Ethambutol 2HCl, Emb dihydrochloride, CL40881

Chemical Properties

Molecular Weight	277.24
Formula	C₁₀H₂₆Cl₂N₂O₂
Cas No.	1070-11-7
Smiles	Cl.Cl.CC[C@H](CO)NCCN[C@H](CC)CO
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

H2O: 51 mg/mL (183.96 mM), Sonication is recommended.

DMSO: 60 mg/mL (216.42 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6070 mL	18.0349 mL	36.0698 mL	180.3492 mL
5 mM	0.7214 mL	3.6070 mL	7.2140 mL	36.0698 mL
10 mM	0.3607 mL	1.8035 mL	3.6070 mL	18.0349 mL
20 mM	0.1803 mL	0.9017 mL	1.8035 mL	9.0175 mL
50 mM	0.0721 mL	0.3607 mL	0.7214 mL	3.6070 mL
100 mM	0.0361 mL	0.1803 mL	0.3607 mL	1.8035 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc