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Search Results for " cab "

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T62316	P-CAB agent 1
	P-CAB agent 1 (compound B19) is a potassium-competitive acid blocker that acts on H+/K+-ATPase (IC50: 60.50 nM). P-CAB agent 1 can be used in the study of acid-related diseases (ARDs).
T72897	P-CAB agent 2
	P-CAB Agent 2 is a potent, orally active potassium-competitive acid blocker (P-CAB) and gastric acid secretion inhibitor that effectively inhibits H+/K+-ATPase activity, showing an IC50 value of <100 nM. It also demonstr...
T72181	P-CAB agent 2 hydrochloride
	P-CAB agent 2 hydrochloride is a potent, orally active potassium-competitive acid blocker (P-CAB) and gastric acid secretion inhibitor. It effectively inhibits H+/K+-ATPase activity, with an IC50 value of <100 nM, and ta...
T30767	CB-181963	CB 181963,CB181963,UNII-6784994L0W,CAB 175
	CB-181963, a new cephalosporin, is an effective antistaphylococcal drug, showing excellent activity against the resistance of MRSA strains to other cephalosporins in planktonic and biofilm cultures.
T8388	Vonoprazan	TAK-438 (free base)	Proton pump
	Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis		Proton pump
T21254	Vonoprazan Fumarate	TAK-438,TAK 438,Vonoprazan Fumurate,TAK438	Proton pump
	Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19...		Proton pump
T2587	Ecabet Sodium	TA-2711E,TA-2711	Reactive Oxygen Species , Antibacterial
	Ecabet Sodium (TA-2711) is a potential new agent in the management of distal colitis.		Reactive Oxygen Species , Antibacterial
T1797	Cabozantinib S-malate	Cabozantinib,XL184,Cabozantinib Malate	Apoptosis , VEGFR , c-Met/HGFR , TAM Receptor , c-Kit
	Cabozantinib S-malate (XL184) is the s-malate salt form of cabozantinib, an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity.		Apoptosis , VEGFR , c-Met/HGFR , TAM Receptor , c-Kit
T31597	Ecabapide	DQ2511,DQ 2511,DQ-2511	Others
	Ecabapide (DQ-2511) is a novel gastrointestinal motility promoter that significantly enhances gastric emptying in SHRSP.Ecabapide activates cyclic GMP-dependent housekeeping Cl- channels in rabbit gastric wall cells.		Others
T5164	Cabozantinib hydrochloride	XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351	VEGFR , FLT , c-Met/HGFR , TAM Receptor , c-Kit , ROR
	Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM).		VEGFR , FLT , c-Met/HGFR , TAM Receptor , c-Kit , ROR
T17220	Vecabrutinib	SNS-062	Tyrosine Kinases , BTK
	Vecabrutinib (SNS-062) is a potent and noncovalent BTK and ITK inhibitor (Kd: 0.3 nM and 2.2 nM, respectively). Vecabrutinib displays an IC50 of 24 nM for ITK.		Tyrosine Kinases , BTK
T6098	Cabotegravir	GSK744,GSK-1265744,S/GSK1265744	HIV Protease
	Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM).		HIV Protease
T2586	Cabozantinib	XL184,BMS-907351	Apoptosis , VEGFR , FLT , c-Met/HGFR , c-RET , TAM Receptor , c-Kit
	Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM). Cabozantinib exhibits both antitumor and antiangiogenic activity...
T11386L	Gemcabene	PD-72953	Others
	Gemcabene (PD-72953) is a lipid-lowering agent with anti-inflammatory activity. Gemcabene lowers low-density lipoprotein cholesterol and triglycerides, raises high-density lipoprotein cholesterol, and decreases pro-infla...		Others
T20068	Decabromodiphenyl ether	NSC 82553,NSC-82553,NSC82553
	Decabromodiphenyl ether is a compound of flame retardant.
T11386	Gemcabene calcium	PD-72953 calcium	Others
	Gemcabene calcium , a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) andexerting anti-inflammator...		Others
TP2454	Decabassianolide
	Decabassianolide is a biochemical.
T30681	CABP	2-CABP,2CABP,2 CABP
	CABP is a transition analog of ribulos-1, 5-diphosphate carboxylase/oxygenase (Rubisco).
T62328	Cabotegravir sodium
	Cabotegravir sodium is a potent inhibitor of HIV integrase and is able to act on HIVADA (IC50: 2.5 nM). cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1 and is less li...
T68551	Cabergoline diphosphate
	Cabergoline diphosphate is a dopamine D2 receptor agonist used for prolactinoma treatment. Cabergoline permits rapid and effective hormonal and tumor control by normalizing prolactin-producing pituitary adenomas levels.
T30680	Cabiotraxetan
	Cabiotraxetan is a therapeutic carrier.
T31279	Decaborane, diammonium salt	Diammonium decaborane
	Decaborane, diammonium salt is a biochemical.
T76786	Cabiralizumab
	Cabiralizumab (FPA 008), an anti-CSF1R monoclonal antibody (MAb), promotes T cell infiltration and boosts antitumor immune responses. It also prevents osteoclast activation, thereby inhibiting bone destruction, and is ut...
T38101	Bisucaberin
	Bisucaberin is a siderophore and bacterial metabolite that has been found inA. haloplanktisand has anticancer activity.1,2It inhibits the growth of L1210 and 1MC carcinoma cells (IC50s = 9.7 and 12.7 μM, respectively) an...
T61623	Ecabet
	Ecabet sodium (TA-2711) is a chemical compound utilized for the clinical treatment of gastrointestinal disease through the suppression of reactive oxygen species (ROS) generation and enhancement of Helicobacter pylori er...
T32700	Levocabastine	Livostin,Bilina
	Levocarbastine is a second-generation H1 receptor antagonist for allergic conjunctivitis. It also acts as a potent selective antagonist for the neurotensin receptor NTS2 and is the first drug to be used to characterize d...
T70808	Cabazitaxel-d6
	Cabazitaxel-d6 is a deuterium labeled cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel binds to and stabilizes tubu...
T31280	Decaborane, ethyl-,	Ethyldecaborane,Decaborane, ethyl-,Ethyldekaboran
	Decaborane, ethyl-, Nonaborane and decaborane cluster anions can enhance the ignition delay in hypergolic ionic liquids and induce hypergolicity in molecular solvents.
T20709	Levocabastine hydrochloride	R50,547,R-50,547,Levocabastine HCl,R 50,547,Livostin
	Levocabastine HCl is an agent with antihistaminic activity.
T2404	Vonoprazan fumarate	TAK-438	ATPase
	Vonoprazan fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase.		ATPase
T2093	PF 03716556	PF-3716556	ATPase
	PF 03716556 (PF-3716556) , an effective and specific P-CAB (potassium-competitive acid blocker), is utilized for the treatment of gastroesophageal reflux disease.		ATPase
T2405	Revaprazan hydrochloride	YH1885	ATPase , COX , Antibacterial
	Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity.		ATPase , COX , Antibacterial
T69613	Ar-H047108 free base
	Ar-H047108 free base is an imidazopyridine potassium competitive acid blocker (P-CAB). This drug may be used to treat early stellate cell activation and veno-occlusive-disease (VOD)-like hepatotoxicity.
T80609	Mecbotamab
	Mecbotamab vedotin (BA3011) is a humanized IgG1-κ antibody engineered to target the AXL receptor tyrosine kinase (AXL). Serving as a conditionally active biologic (CAB), mecbotamab is conjugated to monomethyl auristatin ...
T61643	Vonoprazan hydrochloride
	Vonoprazan hydrochloride, a proton pump inhibitor (PPI), effectively acts as a potassium-competitive acid blocker (P-CAB) with potent antisecretory activity. It notably inhibits H+,K+-ATPase activity in porcine gastric m...

Compounds

P-CAB agent 2 hydrochloride

Synonym: CB 181963,CB181963,UNII-6784994L0W,CAB 175

Target:

Vonoprazan

T8388

Synonym: TAK-438 (free base)

Target: Proton pump

Vonoprazan Fumarate

T21254

Synonym: TAK-438,TAK 438,Vonoprazan Fumurate,TAK438

Target: Proton pump

Ecabet Sodium

T2587

Synonym: TA-2711E,TA-2711

Target: Reactive Oxygen Species, Antibacterial

Cabozantinib S-malate

T1797

Synonym: Cabozantinib,XL184,Cabozantinib Malate

Target: Apoptosis, VEGFR, c-Met/HGFR, TAM Receptor, c-Kit

Ecabapide

T31597

Synonym: DQ2511,DQ 2511,DQ-2511

Target: Others

Cabozantinib hydrochloride

T5164

Synonym: XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351

Target: VEGFR, FLT, c-Met/HGFR, TAM Receptor, c-Kit, ROR

Vecabrutinib

T17220

Synonym: SNS-062

Target: Tyrosine Kinases, BTK

Cabotegravir

T6098

Synonym: GSK744,GSK-1265744,S/GSK1265744

Target: HIV Protease

Cabozantinib

T2586

Synonym: XL184,BMS-907351

Target: Apoptosis, VEGFR, FLT, c-Met/HGFR, c-RET, TAM Receptor, c-Kit

Decabromodiphenyl ether

T20068

Synonym: NSC 82553,NSC-82553,NSC82553

Target:

Gemcabene calcium

T11386

Synonym: PD-72953 calcium

Synonym: 2-CABP,2CABP,2 CABP

Target:

Cabotegravir sodium

T62328

Synonym:

Target:

Cabergoline diphosphate

Decaborane, diammonium salt

T31279

Synonym: Diammonium decaborane

Synonym: Livostin,Bilina

Synonym: Ethyldecaborane,Decaborane, ethyl-,Ethyldekaboran

Target:

Levocabastine hydrochloride

T20709

Synonym: R50,547,R-50,547,Levocabastine HCl,R 50,547,Livostin

Revaprazan hydrochloride

T2405

Synonym: YH1885

Target: ATPase, COX, Antibacterial

Vonoprazan hydrochloride

T61643

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
TQ0096	Scabertopin		Others
	Scabertopin is a sesquiterpene lactone isolated from Gentiana scabra with anticancer and bacteriostatic activities.		Others
T2543	Cabazitaxel	XRP6258,RPR-116258A,TXD 258,taxoid XRP6258	Microtubule Associated , Autophagy
	Cabazitaxel (taxoid XRP6258) is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel.		Microtubule Associated , Autophagy
T14853	Cabergoline	FCE-21336	Dopamine Receptor , 5-HT Receptor , Autophagy
	Cabergoline (FCE-21336) is an ergot derived-dopamine D2-like receptor agonist. It has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).Cabergoline permits rapid and effective hormonal a...		Dopamine Receptor , 5-HT Receptor , Autophagy
TN3556	Cabraleadiol 3-acetate		Others
	Cabraleadiol 3-acetate is a natural product of Aglaia, Meliaceae. The catalog number is TN3556 and the CAS number is 35833-62-6. Cabraleadiol 3-acetate can be used as a reference standard.		Others
TN3560	Cabralealactone		Antifection
	Cabralealactone displays antimycobacterial activity against Mycobacterium tuberculosis, it is weakly cytotoxic to a breast cancer (BC) cell line, it is moderately active against a small-cell lung cancer (NCI-H187) cell l...		Antifection
TN2925	3-Epicabraleadiol		Others
	3-Epicabraleadiol is a natural product of Camellia, Theaceae. The catalog number is TN2925 and the CAS number is 19942-04-2. 3-Epicabraleadiol can be used as a reference standard.		Others
T75567	Cabenoside D
	Cabenoside D (compound 8), a triterpenoid glycoside derived from the methanol extract of lichen root, exhibits anti-inflammatory activity. It effectively inhibits inflammation and the activation of early Epstein-Barr vir...
TN3557	Cabraleadiol		ATPase , Antifection
	Cabraleadiol displays antimycobacterial activity against Mycobacterium tuberculosis, it also is weakly cytotoxic to a breast cancer (BC) cell line. Cabraleadiol inhibits photosystem II (PS II) and induces the appearance ...		ATPase , Antifection
TN3554	Cabazitaxel intermediate		Others
	Cabazitaxel intermediate is a natural product for research related to life sciences. The catalog number is TN3554 and the CAS number is 1354900-65-4.		Others
TN2183	Scabioside C		Others
	Scabioside C is a natural product		Others
TN3555	Caboxine A		Others
	Caboxine A is a natural product of Catharanthus, Apocynaceae. The catalog number is TN3555 and the CAS number is 53851-13-1. Caboxine A can be used as a reference standard.		Others
TN3559	Cabraleahydroxylactone		HSV
	Cabraleahydroxylactone displays antimycobacterial activity against Mycobacterium tuberculosis, it is weakly cytotoxic to a breast cancer (BC) cell line.It shows antiviral activity against herpes simplex virus type-1 with...		HSV
TN1135	Isoscabertopin		Others
	Isoscabertopin has anticancer activity.		Others
TN3561	Cabraleone		Others
	The mixture of cabraleone and ocotillone shows cytotoxicity against HL-60 leukaemia cell line.		Others
TN3558	Cabraleahydroxylactone acetate		Others
	Cabraleahydroxylactone acetate is a natural product for research related to life sciences. The catalog number is TN3558 and the CAS number is 35833-70-6.		Others
TN2926	3-Epicabraleahydroxylactone		Others
	3-Epicabraleahydroxylactone has anti-tumor promoting effect, it has anti-carcinogenic activity by the inhibitory effect on the induction of Epstein-Barr virus early antigen(EBV-EA) by the tumor promoter.		Others

Natural Products

Synonym: XRP6258,RPR-116258A,TXD 258,taxoid XRP6258

Target: Microtubule Associated, Autophagy

Cabergoline

T14853

Synonym: FCE-21336

Target: Dopamine Receptor, 5-HT Receptor, Autophagy

Cabraleadiol 3-acetate

Target: ATPase, Antifection

Cabazitaxel intermediate

Cabraleahydroxylactone

Cabraleahydroxylactone acetate

TN3558

Synonym:

Target: Others

3-Epicabraleahydroxylactone

TN2926

Synonym:

Target: Others

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04021	NPDC1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	NPDC1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.9 kDa and the accession number is Q9NQX5.
TMPJ-00731	Carbonic Anhydrase 1 Protein, Human, Recombinant (His)	Human	E. coli
	Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 p...
TMPH-03569	IcaB Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. N-deacetylation is crucial for attachment of the polysaccharide to the bacterial ce...
TMPY-02955	CABP5 Protein, Human, Recombinant (His)	Human	E. coli
	CABP3, also known as CABP5, belongs to a subfamily of calcium binding proteins, which share similarity to calmodulin. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. ...
TMPH-00551	IL-13 Protein, Equus caballus, Recombinant (His)	Horse	P. pastoris (Yeast)
	IL-13 Protein, Equus caballus, Recombinant (His) is expressed in Yeast.