Powder: -20°C for 3 years | In solvent: -80°C for 2 years
Cabazitaxel is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
20 mg | In stock | $ 51.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Cabazitaxel is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel. |
Cell Research | The cytotoxicity of CBX-loaded ANs and free Cabazitaxel (CBX) is evaluated with MTT assay. Cells are seeded onto a 96-well plate at a density of 3000 cells per well and cultured for 24 h. CBX-loaded ANs and free CBX are diluted to predetermined concentrations with PBS and added into each well. Blank AN, AN-ICG and free CBX solvent (a mixture of Tween-80 and anhydrous alcohol) are added as well to different final concentrations. The incubation continued for another 48 hours. 20 μL MTT solutions (5 mg/mL in PBS) are added into each well and cells are incubated for another 4 hours under 37°C. Subsequently the medium is removed and 150 μL dimethyl sulphoxide (DMSO) is added to dissolve the purple formazan salt crystals. Then the absorbance is measured by a microplate reader at 490 nm. The cells treated with medium are evaluated as controls. |
Source |
Synonyms | TXD 258, taxoid XRP6258, RPR-116258A, XRP6258 |
Molecular Weight | 835.93 |
Formula | C45H57NO14 |
CAS No. | 183133-96-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
H2O: <1 mg/mL
Ethanol: <1 mg/mL
DMSO: 93 mg/mL (111.3 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Cabazitaxel 183133-96-2 Autophagy Cytoskeletal Signaling Microtubule Associated Microtubule/Tubulin taxoid XRP 6258 TXD 258 taxoid XRP6258 RPR-116258A taxoid XRP-6258 XRP 6258 inhibit XRP-6258 XRP6258 Inhibitor inhibitor