Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Gemcabene (PD-72953) is a lipid-lowering agent with anti-inflammatory activity. Gemcabene lowers low-density lipoprotein cholesterol and triglycerides, raises high-density lipoprotein cholesterol, and decreases pro-inflammatory acute-phase protein, C-reactive protei
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 50.00 | |
2 mg | In stock | $ 71.00 | |
5 mg | In stock | $ 109.00 | |
10 mg | In stock | $ 183.00 | |
25 mg | In stock | $ 337.00 | |
50 mg | In stock | $ 559.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 118.00 |
Description | Gemcabene (PD-72953) is a lipid-lowering agent with anti-inflammatory activity. Gemcabene lowers low-density lipoprotein cholesterol and triglycerides, raises high-density lipoprotein cholesterol, and decreases pro-inflammatory acute-phase protein, C-reactive protei |
In vitro | Gemcabene significantly downregulates hepatic mRNA markers of inflammation including TNF-α, MCP-1, MIP-1β, CCR5, CCR2, NF-κB, lipogenesis, fibrosis including TIMP-1 and MMP-2, and lipid modulation including ApoC-III, ACC1, ADH-4 and Sulf-2[2]. |
Synonyms | PD-72953 |
Molecular Weight | 302.41 |
Formula | C16H30O5 |
CAS No. | 183293-82-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 95 mg/mL (314.14 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Gemcabene 183293-82-5 Others Inhibitor PD-72953 inhibit PD 72953 PD72953 inhibitor