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CB-181963

Catalog No. T30767 CAS 635292-67-0

Synonyms: CB 181963, CB181963, UNII-6784994L0W, CAB 175

CB-181963, a new cephalosporin, is an effective antistaphylococcal drug, showing excellent activity against the resistance of MRSA strains to other cephalosporins in planktonic and biofilm cultures.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

CB-181963, CAS 635292-67-0

Pack Size	Availability	Price/USD	Quantity
25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

CB-181963, a new cephalosporin, is an effective antistaphylococcal drug, showing excellent activity against the resistance of MRSA strains to other cephalosporins in planktonic and biofilm cultures.

Synonyms	CB 181963, CB181963, UNII-6784994L0W, CAB 175
Molecular Weight	569.59
Formula	C19H24FN11O5S2
CAS No.	635292-67-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Burall LS, Rodolakis A, Rekiki A, Myers GS, Bavoil PM. Genomic analysis of an attenuated Chlamydia abortus live vaccine strain reveals defects in central metabolism and surface proteins. Infect Immun. 2009 Sep;77(9):4161-7. doi: 10.1128/IAI.00189-09. Epub 2009 Jul 13. PubMed PMID: 19596773; PubMed Central PMCID: PMC2738009. 2. Miller K, Storey C, Stubbings WJ, Hoyle AM, Hobbs JK, Chopra I. Antistaphylococcal activity of the novel cephalosporin CB-181963 (CAB-175). J Antimicrob Chemother. 2005 Apr;55(4):579-82. Epub 2005 Feb 18. PubMed PMID: 15722396. 3. Hoellman DB, Pankuch GA, Appelbaum PC. Antistaphylococcal activity of CB-181963 (CAB-175), an experimental parenteral cephalosporin. Antimicrob Agents Chemother. 2004 Oct;48(10):4037-9. PubMed PMID: 15388474; PubMed Central PMCID: PMC521906. 4. Huang V, Brown WJ, Rybak MJ. In vitro activities of a novel cephalosporin, CB-181963 (CAB-175), against methicillin-susceptible or -resistant Staphylococcus aureus and glycopeptide-intermediate susceptible staphylococci. Antimicrob Agents Chemother. 2004 Jul;48(7):2719-23. PubMed PMID: 15215134; PubMed Central PMCID: PMC434184.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

CB-181963 635292-67-0 CB 181963 CAB175 CB181963 UNII-6784994L0W CAB 175 CAB-175 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.