pharmacologically — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8450	TCN 213	TCN213	NMDAR
	TCN 213 is an antagonist of NMDA receptor that has a selective for NR1/NR2A over NR1/NR2B		NMDAR
T5104	BTSA1		Apoptosis , BCL
	BTSA1 is a BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis.		Apoptosis , BCL
T2131	Articaine hydrochloride	Ultracaine,Articaine HCl,Hoe-045	Sodium Channel
	Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.		Sodium Channel
T1447	Fenclonine	Fenchlonine,PCPA,CP-10188,4-Chloro-DL-phenylalanine,DL-4-Chlorophenylalanine	Hydroxylase
	Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine(CP-10188) acts pharmacologically to dep...		Hydroxylase
T0150	Hydroxyhexamide	(±)-Hydroxyhexamid	Potassium Channel , Drug Metabolite
	Hydroxyhexamide ((±)-Hydroxyhexamid) is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agent.		Potassium Channel , Drug Metabolite
T12145L	N-Desethylsunitinib hydrochloride		VEGFR , PDGFR , c-Kit
	N-Desethylsunitinib hydrochloride is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-competitive VEGFR, PDGFRβ, and KIT inhibitor.		VEGFR , PDGFR , c-Kit
T7806	Licarbazepine	10,11-hydroxy-10,11 Dihydrocarbamezer	Others
	Licarbazepine (10,11-hydroxy-10,11 Dihydrocarbamezer) is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial seizures and bipolar disorders.		Others
T0785	Dexchlorpheniramine Maleate	S-(+)-Chlorpheniramine maleate salt	Dopamine Receptor , 5-HT Receptor , Norepinephrine , Histamine Receptor
	Dexchlorpheniramine Maleate (S-(+)-Chlorpheniramine maleate salt) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It is the pharmacologically active d...
T22431	SU5204	3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one	EGFR , VEGFR , HER
	SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and HER2)		EGFR , VEGFR , HER
T0182L2	(±) Clopidogrel hydrogen sulfate	Plavix,Clopidogrel hydrogen sulfate,Iscover	P2Y Receptor
	(±) Clopidogrel hydrogen sulfate (Iscover) , an antiplatelet agent pharmacologically and structurally analogous to ticlopidine, is used to inhibit blood clots in various conditions such as cerebrovascular disease, periph...		P2Y Receptor
TP1277	Bradykinin		Endogenous Metabolite , Bradykinin Receptor
	Bradykinin is an inflammatory mediator. It is a peptide that causes blood vessels to dilate (enlarge) via the release of prostacyclin, nitric oxide, and Endothelium-Derived Hyperpolarizing Factor. Bradykinin is a physiol...		Endogenous Metabolite , Bradykinin Receptor
T13177	Taquidil
	Tocainide hydrochloride is a sodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is an orally effective antiarrhythmic agent, structurally and ...
T20714	Levolansoprazole	(S)-Lansoprazole,(-)-Lansoprazole	Proton pump
	Levolansoprazole ((S)-Lansoprazole), a proton pump inhibitor, irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50: 5.2 μM). It also inhibits acid formation in isolated canine parietal cells (IC50:...		Proton pump
T1545	Levamlodipine	(S)-Amlodipine,S-amlodipine	Calcium Channel
	Levamlodipine (S-amlodipine) belongs to the dihydropyridine group of calcium channel blockers. Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive and an...		Calcium Channel
TN2080	Pinoresinol	(+)-Pinoresinol	Apoptosis , NF-κB , CDK , p53
	Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative st...		Apoptosis , NF-κB , CDK , p53
T4284	Levamlodipine besylate	(S)-Amlodipine Besylate (103129-82-4(free base))	Calcium Channel
	Levamlodipine besylate ((S)-Amlodipine Besylate (103129-82-4(free base))) , also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive and anti-anginal medication. Levamlodipi...		Calcium Channel
T32886	Lorzafone	Lorzafonum,45-0088S
	Lorzafone is used in the detection & analysis of pharmacologically active benzodiazepines.
T16272	Naproxen etemesil	LT-NS 001,MX 1094	PDE
	Naproxen is a COX-1 and COX-2 inhibitor (IC50s: 8.72 and 5.15 μM, respectively in cell assay). Naproxen etemesil is a lipophilic and non-acidic prodrug of naproxen. It is hydrolyzed to pharmacologically active Naproxen o...		PDE
T32704	Levoleucovorin	levo-Folinic,LFP-754,Levofolinic acid,Levofolene,LFP 754
	Levoleucovorin, as a folate analog, consists of the pharmacologically active isomer of leucovorin.
T21155	Metoprolol acid	Atenolol acid,H117-04,H 117/04,SL 77-010
	Metoprolol acid is a urinary metoprolol metabolite and doesn't work pharmacologically.