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Search Results for " anti-diabetic "

20

Compounds

Cat No. Product Name Synonyms Targets
TN6490 Regaloside C Others
Regaloside C is a glycerol glucoside isolated from Lilium genus with anti-inflammatory properties.
T8345 Carbutamide Others
Carbutamide is a sulfonylurea antidiabetic agent with hypoglycemic activity.
T7704 KY-226 Phosphatase
KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 μM,)
TN1686 Ginsenoside Rg4 Antibacterial
Ginsenoside Rg4 is a natural product
TN1644 Flavanomarein Others
Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea...
T7792 Hispidin Endogenous Metabolite , PKC
Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties
T9921 Infliximab TNF
Infliximab is a humanized antibody against tumor necrosis factor α TNF-α) that is used in the treatment of Crohn's disease and rheumatoid arthritis.
T2316 Omarigliptin MK-3102 Proteasome , DPP-4
Omarigliptin (MK-3102) has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Chronic Renal Insufficiency.
T6237 Trelagliptin SYR-472 Proteasome , DPP-4
Trelagliptin (SYR-472) is a highly specific and long-acting DPP-4 inhibitor.
T3803 Specnuezhenide Nuzhenide,Nuezhenide Others , NF-κB , Wnt/beta-catenin
Specnuezhenide (Nuezhenide) significantly protects human neuroblastoma SH-SY5Y cells from 6-hydroxydopamine-induced neurotoxicity.Nuezhenide is the main inhibitory compound of fruits, it shows a clear inhibitory effect t...
T2755 Rhoifolin Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside Others , p38 MAPK , NF-κB , transporter , IGF-1R , Autophagy
Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
TN7108 Urolithin C Apoptosis , Calcium Channel , Reactive Oxygen Species , IGF-1R , Endogenous Metabolite
Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.
T8408 GKT136901 AK120765 NADPH-oxidase , NADPH
GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
TN2111 Prunin Naringenin 7-0-glucoside Phosphatase , Anti-infection , Virus Protease
Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can...
T2S1158 4,5-Dicaffeoylquinic acid 3,4-Dicaffeoylquinic acid,Isochlorogenic acid C Others , HBV , Endogenous Metabolite
1. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) has antiviral activity, including anti-HIV-1 integrase activity. 2. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) shows anti-hepatotoxic activity.
T6587 Mitiglinide Calcium KAD-1229,S21403 ATPase , Potassium Channel
Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells.
TN6774 Emodin 6-O-β-D-glucoside Glucoemodin Others
Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside ...
T2296 Trelagliptin succinate SYR-472 succinate,SYR472 Proteasome , DPP-4
Trelagliptin succinate (SYR-472 succinate) is a long-acting inhibitor of dipeptidyl peptidase-4 (DPP-4), being developed for the treatment of type 2 diabetes (T2D).
T1530 Mitiglinide calcium hydrate KAD-1229 calcium hydrate,Mitiglinide calcium,S-21403 calcium hydrate Potassium Channel
Mitiglinide calcium hydrate (S-21403 calcium hydrate) is a drug for the treatment of type 2 diabetes. Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) K(ATP) channels in pancreatic ...
T6S1917 Schisandrol B Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B P450 , Reactive Oxygen Species , Autophagy
1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has a...

Compounds

Regaloside C
TN6490
Synonym:
Target: Others
Carbutamide
T8345
Synonym:
Target: Others
KY-226
T7704
Synonym:
Target: Phosphatase
Ginsenoside Rg4
TN1686
Synonym:
Target: Antibacterial
Flavanomarein
TN1644
Synonym:
Target: Others
Hispidin
T7792
Synonym:
Target: Endogenous Metabolite, PKC
Infliximab
T9921
Synonym:
Target: TNF
Omarigliptin
T2316
Synonym: MK-3102
Target: Proteasome, DPP-4
Trelagliptin
T6237
Synonym: SYR-472
Target: Proteasome, DPP-4
Specnuezhenide
T3803
Synonym: Nuzhenide,Nuezhenide
Target: Others, NF-κB, Wnt/beta-catenin
Rhoifolin
T2755
Synonym: Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside
Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy
Urolithin C
TN7108
Synonym:
Target: Apoptosis, Calcium Channel, Reactive Oxygen Species, IGF-1R, Endogenous Metabolite
GKT136901
T8408
Synonym: AK120765
Target: NADPH-oxidase, NADPH
Prunin
TN2111
Synonym: Naringenin 7-0-glucoside
Target: Phosphatase, Anti-infection, Virus Protease
4,5-Dicaffeoylquinic acid
T2S1158
Synonym: 3,4-Dicaffeoylquinic acid,Isochlorogenic acid C
Target: Others, HBV, Endogenous Metabolite
Mitiglinide Calcium
T6587
Synonym: KAD-1229,S21403
Target: ATPase, Potassium Channel
Emodin 6-O-β-D-glucoside
TN6774
Synonym: Glucoemodin
Target: Others
Trelagliptin succinate
T2296
Synonym: SYR-472 succinate,SYR472
Target: Proteasome, DPP-4
Mitiglinide calcium hydrate
T1530
Synonym: KAD-1229 calcium hydrate,Mitiglinide calcium,S-21403 calcium hydrate
Target: Potassium Channel
Schisandrol B
T6S1917
Synonym: Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B
Target: P450, Reactive Oxygen Species, Autophagy
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TargetMol