Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside has anti-inflammatory activities and also may have significant therapeutic benefits against diabetic complications and atherosclerosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 148.00 | |
5 mg | In stock | $ 368.00 | |
10 mg | In stock | $ 550.00 | |
25 mg | In stock | $ 887.00 | |
50 mg | In stock | $ 1,220.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 390.00 |
Description | Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside has anti-inflammatory activities and also may have significant therapeutic benefits against diabetic complications and atherosclerosis. |
In vitro | Emodin-6-O-β-D-glucoside (EG) is a new active compound from Reynoutria japonica. EG was found to suppress the release of HMGB1, the production of tumor necrosis factor (TNF)-α, and the activation of nuclear factor-κB (NF-κB) by HMGB1 in HUVECs |
In vivo | Emodin-6-O-β-D-glucoside (EG) also inhibit HMGB1-mediated hyperpermeability and leukocyte migration in mice. Furthermore, EG also increased the survival times of CLP administered mice. |
Synonyms | Glucoemodin |
Molecular Weight | 432.38 |
Formula | C21H20O10 |
CAS No. | 34298-85-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 65 mg/ml (150.33 mM)
You can also refer to dose conversion for different animals. More
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Emodin 6-O-β-D-glucoside 34298-85-6 Others atherosclerosis Emodin 6OβDglucoside Emodin 6-O-beta-D-glucoside diabetic Reynoutria active Inhibitor Emodin 6-O-b-D-glucoside barrier complications Glucoemodin potent japonica protective anti-inflammatory Emodin 6 O β D glucoside inhibit inhibitor