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Cat No. | Product Name | Synonyms | Targets |
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T32370 | KC 400 | Kaneclor 400,Kanechlor 400,KC-400,KC400 | |
KC 400 consists of polychlorinated biphenyls. | |||
T2137 | Ibudilast | AV-411,KC-404,MN-166 | PDE |
Ibudilast (MN-166)(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor. It is approved for use as an anti-inflammatory in Japan. | |||
T27716 | KC-12615 | KC12615 | |
KC-12615 is an inhibitior of endopeptidase. | |||
T27020 | Cilansetron | KC-9946,KC9946,DU-123265,DU123265 | 5-HT Receptor |
Cilansetron is an effective and selective 5-HT3 receptor antagonist that can be used for related diseases caused by colitis. | |||
T22887 | KC 12291 hydrochloride | Others | |
voltage-gated sodium channel blocker | |||
T70563 | KC-11404 | ||
KC-11404 is an LTB4 inhibitor for the treatment of b-cell leukemias and lymphomas, potently inhibiting histamine, platelet activating factor and 5-lipoxygenase. | |||
T30936 | Cilansetron Hydrochloride | KC-9946,KC9946,KC 9946 | |
Cilansetron Hydrochloride can be used for irritable Bowel Syndrome (IBS) with Diarrhea Predominance. | |||
T34877 | Tifluadom | KC-5103,KC5103,dl-Tifluadom,KC 5103 | |
Tifluadom is a type of kappa-opioid benzodiazepine. | |||
T15139 | DLin-KC2-DMA | Others | |
DLin-KC2-DMA is a cationic/ionizable lipid. Which is used for siRNA delivery. | |||
T3169 | KC7F2 | HIF/HIF Prolyl-Hydroxylase , HIF | |
KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity. | |||
T22888 | KC01 | Others | |
KC01 is an effective and selective inhibitor of ABHD16A. By measuring competitive gel-based ABPP (IC50 values of inhibition of ABHD16A by KC01 and KC02: ~0.2–0.5 μM and >10 μM, respectively). Testing by a PS substrate as... | |||
T70522 | FK-906 HCl | ||
FK-906 HCl is a human renin inhibitor used for the long-term treatment of patients with essential hypertension. | |||
T70561 | FCE-24265 | ||
FCE-24265 is a calcium & thromboxane A2 synthase inhibitor. | |||
T9778 | KCNQ1 activator-1 | Potassium Channel | |
2-Piperidinecarboxamide, N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-(phenylsulfonyl)- is a potent KCNQ1 channel activator that can be used in long QT syndrome (LQTS) studies. | |||
T8376 | PKCβ inhibitor 1 | KUN79359 | Apoptosis , PKC |
PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2, respectively). | |||
T5817 | PKC-theta inhibitor hcl | PKC-theta inhibitor | PKC |
PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM). | |||
TP1956L | PKC ζ pseudosubstrate acetate | PKC ζ pseudosubstrate acetate (799764-07-1 free base) | PKC |
PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide. Consists of amino acids 113 - 129 of PKC ζ pseudosubstrate domain linked by... | |||
T12071 | MKC9989 | IRE1 | |
MKC9989 is an inhibitor of Hydroxy aryl aldehydes (HAA). MKC9989 also inhibits IRE1α with an IC50 of 0.23 to 44 μM. | |||
T78575 | KCL-286 | Retinoid Receptor | |
KCL-286 is an orally available and potent retinoic acid receptor beta agonist for the amelioration of spinal cord injury (SCI). | |||
T35827L | PKCε Inhibitor Peptide acetate | PKCε Inhibitor Peptide acetate(182683-50-7 Free base) | PKC |
PKCε Inhibitor Peptide acetate is a selective PKCε inhibitor containing the site for its specific receptor for activated C kinase (RACK). PKCε Inhibitor Peptide acetate inhibits the translocation of PKCε, but not α-, β-,... | |||
T9863 | PKCiota-IN-2 | PKCiota-IN-49 | PKC |
PKCiota-IN-2 (PKCiota-IN-49) is a selective and potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively | |||
T8554 | KCC-07 | DNA Alkylator/Crosslinker | |
KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenes... | |||
T9400 | KCNQ2/3 activator-1 | Others | |
KCNQ2/3 activator-1 is a Kv7.2/Kv7.3 (KCNQ2/3) potassium channel activator. | |||
T15594 | MKC8866 | IRE1 | |
MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29 μM in human vitro). MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibit prostate ca... | |||
TQ0101 | MKC3946 | IRE1 | |
MKC3946 is an effective and soluble IRE1α inhibitor which triggered modest growth inhibition in multiple myeloma cell lines. | |||
T12494 | PKC-IN-1 | PKC | |
PKC-IN-1 is an ATP-competitive and reversible conventional PKC enzymes inhibitor (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with IC50s of 2.3, 8.1, 7.6, 25.6, 57.5, 314, 808 nM, respectively). | |||
T9831 | MKC-1 | Ro-31-7453 | Apoptosis , Akt , Microtubule Associated , mTOR |
MKC-1 (Ro-31-7453) is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the format... | |||
T8764 | PKC-iota inhibitor 1 | PKC | |
PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM) | |||
T12504 | (+)-KCC2 blocker 1 | Potassium Channel | |
(+)-KCC2 blocker 1 is a selective blocker of KCC2 (IC50 = 0.4 μM). | |||
TP1955L | PKC β pseudosubstrate acetate | Protein kinase C beta pseudosubstrate,PKC beta pseudosubstrate,PKC β pseudosubstrate acetate (172308-76-8 Free base) | PKC |
PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC. | |||
T62289 | PI3KC2α-IN-1 | ||
PI3KC2α-IN-1 is a potent inhibitor of PI3KC2α with an IC50 value of 95 nM. PI3KC2α-IN-1 interacts with the ATP binding site of PI3KC2α. PI3KC2α-IN-1 impairs the kinetics of endocytosis and membrane remodelling. PI3KC2α-I... | |||
T72919 | PKCiota-IN-1 | ||
PKCiota-IN-1 is a potent inhibitor of PKCiota (PKC-ι), exhibiting an IC50 of 2.7 nM. Additionally, it displays inhibitory activity against PKC-α and PKC-ε, with IC50 values of 45 nM and 450 nM, respectively. | |||
T81451 | PKCd (8-17) | ||
PKCd (8-17) is a bioactive peptide originating from the V1 domain of protein kinase C (PKC)d. It impedes phorbol 12-myristate 13-acetate (PMA)-stimulated PKCd translocation and activation, which mitigates ischemic injury... | |||
T80511 | PKCε inhibitor peptide,myristoylated | Myr‐PKCɛ- | PKC |
Myristoylated PKCε inhibitor peptide (Myr-PKCε-) is a cell-permeable inhibitor consisting of a peptide linked to myristic acid that specifically inhibits protein kinase C epsilon (PKCε), consequently diminishing nitric o... | |||
T81449 | PKC-ε translocation inhibitor peptide | PKC | |
PKC-ε Translocation Inhibitor Peptide is a selective modulator that controls the FcγR-mediated internalization rate of opsonized beads without affecting FcαR trafficking [1]. | |||
T75850 | JKC363 TFA | ||
JKC363 TFA is a selective melanocortin MC4 receptor antagonist that exhibits a 90-fold higher affinity for the MC4 receptor (IC50=0.5 nM) compared to the MC3 receptor (44.9 nM). This compound effectively inhibits the α-M... | |||
T80509 | PKC 20-28,myristoylated | Myristoylated protein kinase C inhibitor 20-28 | PKC |
Myristoylated protein kinase C inhibitor 20-28 (PKC 20-28,myristoylated) is a cell-permeable inhibitor of protein kinase C, utilized in cancer research [1]. | |||
T80070 | PKCβII Peptide Inhibitor I | PKC | |
PKCβII Peptide Inhibitor I, a specific PKCβII inhibitor, exhibits cardioprotective properties in a rat cardiac ischemia/reperfusion injury model and mitigates vascular endothelial dysfunction [1]. | |||
T35826 | PKC fragment (530-558) | ||
PKC fragment (530-558) is a peptide fragment of protein kinase C (PKC) and is a potent PKC activator. Protein Kinase C (530-558) significantly inhibits osteoclastic bone resorption. | |||
T34413 | KCL-440 | RS57639,RS-57639,RS 57639 | |
RS 57639 is a bioactive chemical. | |||
T23693 | AKCI | ||
AKCI is a PPI inhibitor that acts by targeting the AURKC-IκBα interaction. | |||
T24258 | KCG 1 | KCG-1,KCG1 | |
KCG 1 is a keto-C-glycoside drug with antiproliferative and cytotoxic properties on tumor cells. KCG1 was 25-125 times more cytostatic on epithelial cells than on lymphoma. | |||
T70544 | MKC-963 (R-isomer) | ||
MKC-963 is a platelet aggregation inhibitor and autoinducer of CYP3A4. | |||
TP1955 | PKC β pseudosubstrate | ||
Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM). Consists of amino acids 19 - 31 of PKC pseudosubstrate domain linked by a disulphide bridge to a cell permeabilisation Antennapedia domain v... | |||
TP2245 | Endostatin (84-114)-NH2 (JKC367) | Others | |
Endostatin is a potent inhibitor of primary tumor growth and endothelial cell proliferation and migration. Recombinant endostatin potently inhibited angiogenesis, maintains metastases at a low level, and suppressed tumor... | |||
T80248 | PKCε (85-92) | PKC | |
PKCε (85-92) is a biologically active peptide that functions as a specific activator of ε-PKC and induces MARCKS phosphorylation in wild-type cells, but does not affect MARCKS phosphorylation in cells derived from knocko... | |||
TP2011 | JKC363 | JKC 363 | |
Potent and selective melanocortin MC4 receptor antagonist (IC50 values are 0.5 and 44.9 nM at MC4 and MC3 respectively) that antagonizes the effects of α-MSH. Suppresses thyrotropin-releasing hormone (TRH) release, atten... | |||
T80504 | ɛPKC(85–92),Myristoylated | PKC | |
PKC(85-92),Myristoylated is a myristic acid-conjugated, cell-permeable peptide activator of PKC that has been shown to increase nitric oxide (NO) release in cultured human umbilical vein endothelial cells (HUVECs) [1]. | |||
T78594 | (Z)-KC02 | ||
(Z)-KC02 is an ABHD16A inhibitor which targets the enzyme responsible for producing lysophosphatidylserine (lyso-PS), a lipid involved in regulating immune and neurological functions. This compound is linked to the mitig... | |||
T71993 | PKC-9 | ||
PKC-9 is a PKC-zeta inhibitor 9. |
Cat No. | Product Name | Species | Expression System |
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TMPK-00678 | CALCA/CGRP Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Specific fragments of methylation changes in the target gene (Calca) were identified by IGV analysis. CGRP was applied to compare the effects on ASCs-T2DM morphology via phalloidin staining, proliferation through CCK-8 a... | |||
TMPY-04120 | Procalcitonin/CALCA Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
Procalcitonin/CALCA Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 39.2 kDa and the accession number is P01258-1. | |||
TMPY-00066 | Procalcitonin/CALCA Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Procalcitonin/CALCA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.2 kDa and the accession number is P01258-1. | |||
TMPY-00433 | CXCL1 Protein, Mouse, Recombinant | Mouse | E. coli |
CXCL1 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.3 kDa and the accession number is A2RTH0. | |||
TMPJ-00006 | CXCL1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Growth-regulated alpha protein (CXCL1,KC), is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fibroblasts by platelet-derived growth factor. The N-terminal ... | |||
TMPY-04455 | PKC iota Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Protein kinase C iota type, also known as Atypical protein kinase C-lambda/iota, aPKC-lambda/iota and PRKCI, is a cytoplasm, membrane and nucleus protein which belongs to the protein kinase superfamily, AGC Ser/Thr prote... | |||
TMPY-00945 | TrkC Protein, Human, Recombinant (His) | Human | HEK293 Cells |
TrkC Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.1 kDa and the accession number is Q16288-2. | |||
TMPH-01028 | KCNMA1 Protein, Human, Recombinant | Human | E. coli |
KCNMA1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.2 kDa and the accession number is Q12791. | |||
TMPH-03603 | KcsA Protein, S. coelicolor, Recombinant (His) | Streptomyces coelicolor | E. coli |
Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel. KcsA Protein, S. coelicolor, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted... | |||
TMPY-03811 | KCT2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
C5orf15 (Chromosome 5 Open Reading Frame 15, also known as KCT2) is a Protein Coding gene. KCT2 gene maps to human chromosome 5q31.1 and is conserved in human, chimpanzee, cow, rat, and chicken. KCT2 is a 265 amino acid ... | |||
TMPH-01890 | KCNA1 Protein, Human, Recombinant (His) | Human | E. coli |
KCNA1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 22.2 kDa and the accession number is Q09470. | |||
TMPY-04456 | PKC nu Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Serine/threonine-protein kinase D3, also known as Protein kinase C nu type, Protein kinase EPK2, PRKD3, EPK2 and PRKCN, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr pro... | |||
TMPH-00476 | DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc) | Dictyostelium discoideum | E. coli |
DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPJ-01074 | PKCE Protein, Human, Recombinant (His) | Human | E. coli |
Protein Kinase C Epsilon type is a member of the serine- and threonine-specific protein kinase family that can be activated by calcium and the second messenger diacylglycerol. Protein Kinase C Epsilon contains these doma... | |||
TMPH-01938 | PRKCD Protein, Human, Recombinant (His) | Human | E. coli |
PRKCD Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-02748 | KCP Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. In contrast, it inhibits both the activin-A and TGFB1-mediated signaling pathways. KCP Protein, Mouse, Recombinant (His & Myc) is expressed in E.... | |||
TMPH-01891 | KCNE2 Protein, Human, Recombinant (His) | Human | E. coli |
KCNE2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 17.3 kDa and the accession number is Q9Y6J6. | |||
TMPY-01223 | TrkC Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
TrkC Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.1 kDa and the accession number is Q6VNS1-1. | |||
TMPH-02309 | KCNAB2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
KCNAB2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 57.0 kDa and the accession number is Q13303. | |||
TMPH-01889 | KCNK3 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassi... | |||
TMPY-00944 | TrkC Protein, Human, Recombinant (His & hFc) | Human | HEK293 Cells |
TrkC Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 72.5 kDa and the accession number is Q16288-2. | |||
TMPJ-00011 | CXCL2 Protein, Mouse, Recombinant | Mouse | E. coli |
C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin... |