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AKCI

Catalog No. T23693   CAS 669750-88-3

AKCI is a PPI inhibitor that acts by targeting the AURKC-IκBα interaction.

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AKCI Chemical Structure
AKCI, CAS 669750-88-3
Pack Size Availability Price/USD Quantity
5 mg 6-8 weeks $ 1,070.00
50 mg 6-8 weeks $ 2,180.00
100 mg 6-8 weeks $ 2,800.00
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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.
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Biological Description
Chemical Properties
Storage & Solubility Information
Description AKCI is a PPI inhibitor that acts by targeting the AURKC-IκBα interaction.
Molecular Weight 369.46
Formula C19H27N7O
CAS No. 669750-88-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

TargetMolReferences and Literature

1. Patthy A, Molnár T, Porrogi P, Naudé R, Gráf L. Isolation and characterization of a protease inhibitor from Acacia karroo with a common combining loop and overlapping binding sites for chymotrypsin and trypsin. Arch Biochem Biophys. 2015 Jan 1;565:9-16. doi: 10.1016/j.abb.2014.11.001. Epub 2014 Nov 8. PubMed PMID: 25447841. 2. Ulu SM, Ahsen A, Akcı Ö, Yaman F, Demir K, Yaman G, Yüksel Ş, Acartürk G. The relationship between dipping-non-dipping arterial blood pressure pattern and frequency of restless leg syndrome with related factors. Anatol J Cardiol. 2015 Apr;15(4):284-8. doi: 10.5152/akd.2014.5381. Epub 2014 Apr 16. PubMed PMID: 25413225; PubMed Central PMCID: PMC5336836. 3. Han EH, Min JY, Yoo SA, Park SJ, Choe YJ, Yun HS, Lee ZW, Jin SW, Kim HG, Jeong HG, Kim HK, Kim ND, Chung YH. A small-molecule inhibitor targeting the AURKC-IκBα interaction decreases transformed growth of MDA-MB-231 breast cancer cells. Oncotarget. 2017 Jun 29;8(41):69691-69708. doi: 10.18632/oncotarget.18883. eCollection 2017 Sep 19. PubMed PMID: 29050234; PubMed Central PMCID: PMC5642509.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

AKCI 669750-88-3 inhibitor inhibit

 

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