Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MKC-1 (Ro-31-7453) is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the formation of the mitotic spindle, which may result in
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 87.00 | |
5 mg | In stock | $ 213.00 | |
10 mg | In stock | $ 313.00 | |
25 mg | In stock | $ 542.00 | |
50 mg | In stock | $ 782.00 | |
100 mg | In stock | $ 1,090.00 | |
500 mg | In stock | $ 2,190.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 235.00 |
Description | MKC-1 (Ro-31-7453) is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the formation of the mitotic spindle, which may result in |
Synonyms | Ro-31-7453 |
Molecular Weight | 400.39 |
Formula | C22H16N4O4 |
CAS No. | 125313-92-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (137.36 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
MKC-1 125313-92-0 Apoptosis Cytoskeletal Signaling PI3K/Akt/mTOR signaling Akt Microtubule Associated mTOR inhibit Ro-31-7453 Protein kinase B PKB renal cell cancer Caki-1 Mammalian target of Rapamycin MKC1 MKC 1 orally active Microtubule/Tubulin pancreatic cancer Inhibitor inhibitor