store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PKCε Inhibitor Peptide acetate is a selective PKCε inhibitor containing the site for its specific receptor for activated C kinase (RACK). PKCε Inhibitor Peptide acetate inhibits the translocation of PKCε, but not α-, β-, and δPKC.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 98.00 | |
2 mg | In stock | $ 143.00 | |
5 mg | In stock | $ 197.00 | |
10 mg | In stock | $ 327.00 | |
25 mg | In stock | $ 552.00 | |
50 mg | In stock | $ 793.00 | |
100 mg | In stock | $ 1,090.00 |
Description | PKCε Inhibitor Peptide acetate is a selective PKCε inhibitor containing the site for its specific receptor for activated C kinase (RACK). PKCε Inhibitor Peptide acetate inhibits the translocation of PKCε, but not α-, β-, and δPKC. |
In vitro | PKCε Inhibitor Peptide acetate(1 µM; 24 hours) significantly inhibits Oleic acid-induced connexin 43 Ser368 phosphorylation and prevents Oleic acid-induced gap junction disassembly in cardiomyocytes[1]. |
In vivo | In C57BL/6J mice transplanted the hearts of FVB mice, PKCε Inhibitor Peptide acetate (20 mg/kg/day; osmotic pumps s.c.) significantly improved the beating score throughout the treatment. PKCε Inhibitor Peptide acetate treatment almost abolished the rise in pro-fibrotic cytokine, TGF-β, and monocyte recruiting chemokine MCP-1 levels. PKCε Inhibitor Peptide acetate reduced the infiltration of macrophages and T cells into the cardiac grafts and decreased parenchymal fibrosis[2]. |
Synonyms | PKCε Inhibitor Peptide acetate(182683-50-7 Free base) |
Molecular Weight | 904.02 |
Formula | C39H69N9O15 |
store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PKCε Inhibitor Peptide acetate Chromatin/Epigenetic Cytoskeletal Signaling PKC PKCε Inhibitor Peptide Acetate PKCε Inhibitor Peptide acetate(182683-50-7 Free base) inhibitor inhibit