Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
2 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 126.00 | |
25 mg | In stock | $ 247.00 | |
50 mg | In stock | $ 393.00 | |
100 mg | In stock | $ 585.00 | |
500 mg | In stock | $ 1,270.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 75.00 |
Description | KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling. |
In vitro | In vitro, KCC-07 treatment Medulloblastomas (MB) cells?clearly inhibited MB cell growth, consistent with induction of anti-proliferative BAI1/p53/p21 signaling |
Cell Research | KCC-07?treatment?Medulloblastomas (MB) cells, Concentration with?10 μM and?Incubation Time with?72 hours |
Molecular Weight | 269.32 |
Formula | C14H11N3OS |
CAS No. | 315702-75-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (83.54 mM)
You can also refer to dose conversion for different animals. More
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KCC-07 315702-75-1 DNA Damage/DNA Repair DNA Alkylator/Crosslinker KCC07 BAI1 p53 inhibit ADGRB1 anticancer Inhibitor MBD2 anti-proliferative ADGR KCC 07 brain-penetrant inhibitor