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KCC-07

Catalog No. T8554 CAS 315702-75-1

Purity 99.93% Datasheet

KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling.

KCC-07, CAS 315702-75-1

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5 mg	In stock	209.00
25 mg	In stock	625.00

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Purity 98.00%

COA Datasheet

Purity 99.93%

HNMR LCMS COA Datasheet

Biological Description

Chemical Properties

Storage & Solubility Information

Description	KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling.
Targets&IC50	MBD2 (methyl-CpG-binding domain protein 2), Others,
Cell Research	KCC-07 treatment Medulloblastomas (MB) cells， Concentration with 10 μM and Incubation Time with 72 hours

Appearance	solid
Molecular Weight	269.32
Formula	C14H11N3OS
CAS No.	315702-75-1

Storage

-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Dan Zhu, et al. BAI1 Suppresses Medulloblastoma Formation by Protecting p53 From Mdm2-Mediated Degradation. Cancer Cell. 2018 Jun 11;33(6):1004-1016.e5.

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Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.