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PKC ζ pseudosubstrate acetate

Catalog No. TP1956L CAS TP1956L

Synonyms: PKC ζ pseudosubstrate acetate (799764-07-1 free base)

PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide. Consists of amino acids 113 - 129 of PKC ζ pseudosubstrate domain linked by a disulphide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the inhibitor peptide. Once inside the cell, the disulphide bonds are subjected to reduction in the cytoplasm leading to release of the inhibitor peptide. Induces mast cell degranulation by a PKC ζ-independent pathway.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

PKC ζ pseudosubstrate acetate Chemical Structure

PKC ζ pseudosubstrate acetate, CAS TP1956L

Pack Size	Availability	Price/USD
1 mg	In stock	$ 133.00
5 mg	In stock	$ 302.00
10 mg	In stock	$ 453.00
25 mg	In stock	$ 747.00
50 mg	In stock	$ 1,050.00
100 mg	In stock	$ 1,420.00
500 mg	In stock	$ 2,830.00

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Purity: 98.78%

Biological Description

Chemical Properties

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Description

Synonyms	PKC ζ pseudosubstrate acetate (799764-07-1 free base)
Molecular Weight	1778.10
Formula	C78H132N30O18
CAS No.	TP1956L

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Laudanna et al (1998) Evidence of ζ protein kinase C involvement in polymorphonuclear neutrophil integrin-dependent adhesion and chemotaxis. J.Biol.Chem 273 30306 PMID: 2. Lim et al (2008) A myristoylated pseudosubstrate peptide of PKC-ζ induces degranulation in HMC-1 cells independently of PKC-ζ activity. Life Sci. 82 733 PMID: 3. Theodore et al (1995) Intraneuronal delivery of protein kinase C pseudosubstrate leads to growth cone collapse. J.Neurosci. 15 7158 PMID:

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

PKC ζ pseudosubstrate acetate TP1956L Chromatin/Epigenetic Cytoskeletal Signaling PKC PKC ζ pseudosubstrate acetate (799764-07-1 free base) PKC ζ pseudosubstrate Acetate inhibitor inhibit

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