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Cat No. | Product Name | Synonyms | Targets |
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T11337 | Fumarate hydratase-IN-1 | Mitochondrial Metabolism | |
Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor with antiproliferative activity and can be used to study cellular activity. | |||
T60022 | Aromatase-IN-2 | Others | |
Aromatase-IN-2 has anti-inflammatory, antitumor and antiasthmatic effects. | |||
T15374 | Ipatasertib dihydrochloride | GDC-0068 dihydrochloride,RG-7440 dihydrochloride | Akt , PKA |
Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive inhibitor of pan-Akt (IC50s: 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively). | |||
T78835 | Phosphatase-IN-1 | Antifungal | |
Phosphatase-IN-1 (compound II-8), a propranolol derivative, acts as an inhibitor of phosphatidate phosphatase (Pah). It binds to MoPah1 with an affinity constant of 19.8 μM, demonstrating growth inhibition of plant patho... | |||
T60006 | Aromatase inhibitor 23 | Others | |
Aromatase inhibitor 23 is an inhibitor that target protein-protein interactions in RAD51 family of recombinases. | |||
T6252 | Ipatasertib | GDC-0068,RG7440 | Akt |
Ipatasertib (GDC-0068) (GDC-0068), a highly specific pan-Akt inhibitor, targets Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM, respectively. | |||
T3351 | Onatasertib | CC223,CC 223,CC-223 | Apoptosis , c-Fms , DNA-PK , FLT , PI3K , mTOR |
Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity. Onatasertib inhibits the activity of mTOR, which may result in the induction of tumor cell apoptosis and a decrease in tumor ce... | |||
T61463 | Monoamine oxidase/Aromatase-IN-1 | ||
Monoamine oxidase/Aromatase-IN-1 (compound 2q) is a potent dual inhibitor of monoamine oxidase (MAO) and aromatase, with IC50 values of 39 nM and 31 nM for MAO-B and aromatase, respectively. It holds significant potentia... | |||
T62237 | Steroid sulfatase-IN-4 | ||
Steroid sulfatase-IN-4 (Compound 16) is an irreversible inhibitor of steroid sulfatase (STS) that acts on human STS (IC50: 25 nM). steroid sulfatase-IN-4 can be used to study endometriosis. | |||
T61212 | Steroid sulfatase-IN-2 | ||
Steroid sulfatase-IN-2 is an active inhibitor of steroid sulfatase (STS), demonstrating an IC50 value of 109.5 nM. Its potential application lies in hormone-dependent cancer research, specifically estrogen-dependent brea... | |||
T61444 | Nonsteroidal aromatase inhibitor 1 | ||
Nonsteroidal aromatase inhibitor 1 (Compound 13h) effectively inhibits the enzyme CYP19A1 with an IC50 value of 0.09 nM. Due to its potent inhibitory activity, Nonsteroidal aromatase inhibitor 1 holds promise for researc... | |||
T27621 | Ipatasertib HCl | GDC0068,RG 7440,GDC 0068,RG-7440,GDC-0068,RG7440 | |
Ipatasertib is an orally active, potent and selective Akt inhibitor with antitumor activity. Inhibition of Akt activity by Ipatasertib resulted in blockade of cell-cycle progression and reduced viability of cancer cell l... | |||
T61686 | Steroid sulfatase-IN-3 | ||
Steroid sulfatase-IN-3 (compound 1q) is a highly effective Steroid sulfatase (STS) inhibitor, exhibiting an IC 50 value of 25.8 nM. This compound also demonstrates antiproliferative properties against T-47D estrogen-depe... | |||
T81091 | Steroid sulfatase-IN-5 | ||
Steroid sulfatase-IN-5 (compound 10b), an inhibitor of steroid sulfatase (STS) with an IC50 of 0.32 nM, effectively suppresses T-47D breast cancer cell proliferation, demonstrating an IC50 value of 35.7 μM. This compound... | |||
T81090 | Steroid sulfatase-IN-6 | ||
Steroid Sulfatase-IN-6 (Compound 10c) serves as an irreversible steroid sulfatase (STS) inhibitor, exhibiting a K i value of 0.4 nM against human placenta STS, and is applicable in tumor disease research [1]. | |||
T61716 | Steroid sulfatase/17β-HSD1-IN-1 | ||
Steroid sulfatase/17β-HSD1-IN-1 is a highly effective inhibitor of both steroid sulfatase and 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) activities, displaying an IC50 value of 28 nM against cellular human steroi... | |||
T70552 | Ipatasertib tosylate | ||
Ipatasertib, also known as GDC0068, is an orally active, potent and selective Akt inhibitor. GDC-0068 blocked Akt signaling both in cultured human cancer cell lines and in tumor xenograft models. Inhibition of Akt acti... | |||
T61687 | Steroid sulfatase-IN-1 | ||
Steroid sulfatase-IN-1 is a highly potent and orally active inhibitor of the enzyme Steroid sulfatase, with an impressive IC50 value of 1.71 μM. This compound exhibits notable antitumor activity, achieving a TGI (tumor g... | |||
T81092 | Steroid sulfatase/17β-HSD1-IN-5 | ||
Steroid sulfatase/17β-HSD1-IN-5 serves as an irreversible inhibitor of steroid sulfatase (STS) and a reversible, selective inhibitor of 7β-hydroxysteroid dehydrogenase type1 (17β-HSD1), exhibiting IC50 values of 43 nM fo... | |||
T62236 | Steroid sulfatase/17β-HSD1-IN-3 | ||
Steroid sulfatase/17β-HSD1-IN-3 (compound 19) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1). Steroid sulfatase/17β-HSD1-IN-3 can be used to study endometriosis and ... | |||
T81089 | Steroid sulfatase-IN-7 | ||
Steroid sulfatase-IN-7 is an irreversible inhibitor of steroid sulfatase (STS), demonstrating potent activity with an IC50 of 0.05 nM against human placental STS, rendering it suitable for application in cancer research ... | |||
T18053 | Ipatasertib-NH2 | RG7440-NH2,GDC-0068-NH2 | Others |
Ipatasertib-NH2 (GDC-0068-NH2;RG7440-NH2) is a ligand for target protein AKT for PROTAC, binds to lenalidomide, a ligand of ubiquitin E3 ligase cereblon (CRBN), via a ten-hydrocarbon linker to form INY-03-041 to degrade ... | |||
T61979 | Steroid sulfatase/17β-HSD1-IN-4 | ||
Steroid sulfatase/17β-HSD1-IN-4 (compound 37) is a potent dual inhibitor of steroid sulfatase ( STS ) and 17β-hydroxysteroid dehydrogenase type 1 ( 17β HSD1 ). Steroid sulfatase/17β-HSD1-IN-4 irreversibly inhibits hSTS a... | |||
T76173 | Inorganic pyrophosphatase | ||
Inorganic pyrophosphatase (PPase), key for RNA preparation in in vitro transcription reactions and critical in biochemical studies for nucleic acid and protein synthesis [1], hydrolyzes pyrophosphate (PPi) into phosphate... | |||
T76163 | Arylsulfatase | ||
Arylsulfatase, a type I sulfatase enzyme found in both prokaryotes and eukaryotes, is frequently utilized in biochemical research [1]. | |||
T67036 | Acid phosphatase | ||
Acid phosphatase is a useful organic compound for research related to life sciences. The catalog number is T67036 and the CAS number is 9001-77-8. | |||
T11336 | Fumarate hydratase-IN-2 sodium salt | Others | |
Fumarate hydratase-IN-2 sodium salt (compound 3) is a cell-permeable and competitive fumarate hydratase inhibitor ( K i =4.5 μM). Fumarate hydratase-IN-2 sodium salt has nutrient-dependent cytotoxicity [1]. | |||
T38393 | Ipatasertib-NH2 dihydrochloride | RG7440-NH2 dihydrochloride,Ipatasertib-NH2 dihydrochloride,GDC-0068-NH2 dihydrochloride | |
Ipatasertib-NH2 dihydrochloride is a ligand for the target protein AKT in PROTAC INY-03-041. INY-03-041 consists of Ipatasertib-NH2, a ten-hydrocarbon linker, and the CRBN ligand Lenalidomide, which acts as an E3 ubiquit... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35951 | Alkaline Phosphatase | Others | |
Alkaline Phosphatase is an ubiquitous membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at basic pH values. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03000 | ATase Protein, Mycobacterium tuberculosis, Recombinant (His) | Mycobacterium tuberculosis | E. coli |
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. ATase Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis ta... | |||
TMPY-00663 | Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is A0A024RAB4. | |||
TMPY-00828 | Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfat... | |||
TMPY-02650 | Alkaline phosphatase Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Alkaline phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54 kDa and the accession number is P09923. | |||
TMPK-00639 | Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPY-00570 | Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyro... | |||
TMPH-00265 | Ferrochelatase, mitochondrial Protein, Bovine, Recombinant (His & Myc & SUMO) | Bovine | E. coli |
Catalyzes the ferrous insertion into protoporphyrin IX. Ferrochelatase, mitochondrial Protein, Bovine, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Mycd tag. The predi... | |||
TMPK-00802 | Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-00803 | Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPH-00956 | Aromatase/CYP19A1 Protein, Human, Recombinant (His) | Human | E. coli |
Aromatase/CYP19A1 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPK-00684 | Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-00801 | Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPH-00685 | Exopolyphosphatase Protein, E. coli O6:H1, Recombinant (His) | E. coli | E. coli |
Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain. Exopolyphosphatase Protein, E. coli O6:H1, Recombinant (His) is expressed in E. coli expression syst... | |||
TMPH-00568 | 8-oxo-dGTP diphosphatase Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
8-oxo-dGTP diphosphatase Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.9 kDa and the accession number is P08337. | |||
TMPK-00804 | Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPY-02003 | FH/Fumarate Hydratase Protein, Human, Recombinant (His) | Human | E. coli |
Fumarate Hydratase (FH) is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extende... | |||
TMPY-02155 | Prostatic Acid Phosphatase Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Prostatic Acid Phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is P15309-2. | |||
TMPH-03468 | D-serine dehydratase Protein, Salmonella heidelberg, Recombinant (His & SUMO) | Salmonella heidelberg | E. coli |
D-serine dehydratase Protein, Salmonella heidelberg, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.3 kDa and the accession number is B4TA53... | |||
TMPK-00855 | Alkaline Phosphatase (Germ type) /ALPG Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPY-02713 | Alkaline phosphatase Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Alkaline phosphatase Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 79.5 kDa and the accession number is P09923. | |||
TMPK-00796 | Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag) | Human | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPH-03455 | Polyphosphatase/PPX1 Protein, S. cerevisiae, Recombinant (His) | Saccharomyces cerevisiae | E. coli |
Degradation of inorganic polyphosphates. | |||
TMPH-01332 | Ferrochelatase Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Catalyzes the ferrous insertion into protoporphyrin IX. Ferrochelatase Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.6... | |||
TMPH-00618 | Exopolyphosphatase Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain. Has a strong preference for long-chain polyphosphates and has only weak affinity for smaller size po... | |||
TMPH-03236 | Alkaline phosphatase/ALPL Protein, Rat, Recombinant (His & SUMO) | Rat | E. coli |
Alkaline phosphatase/ALPL Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 69.5 kDa and the accession number is P08289. | |||
TMPY-00594 | Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 80.3 kDa and the accession number is B7XGA6. | |||
TMPK-01326 | Alkaline Phosphatase (Placental type) /ALPP Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPH-00609 | DITP/XTP pyrophosphatase Protein, E. coli, Recombinant (His & Myc & SUMO) | E. coli | E. coli |
dITP/XTP pyrophosphatase Protein, E. coli, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 41.0 kDa and the accession number is... | |||
TMPJ-00784 | Alkaline Phosphatase Protein, Human, Recombinant (aa 23-506, His) | Human | HEK293 Cells |
ALPP is a membrane protein and exits as a homodimer. ALPP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It has been shown to play a rol... | |||
TMPH-03161 | Alkaline Phosphatase Protein, Prevotella intermedia, Recombinant (GST & His & Myc) | Prevotella intermedia | E. coli |
Acts against tyrosine-phosphatases. Alkaline Phosphatase Protein, Prevotella intermedia, Recombinant (GST & His & Myc) is expressed in E. coli expression system with N-10xHis-GST and C-Myc tag. The predicted molecular we... | |||
TMPY-00446 | Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is B7XGA6. | |||
TMPH-00673 | NADH pyrophosphatase Protein, E. coli O157:H7, Recombinant (His) | E. coli | E. coli |
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosph... | |||
TMPY-02131 | Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST) | Human | E. coli |
The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine protein phosphatase family are involved in the regulation of im... | |||
TMPY-02672 | Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q8CE08-1. |
Cat No. | Product Name | ||
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L9100 | Phosphatase Inhibitor Library | 79 compounds | |
A collection of 79 phosphatase inhibitors with known activity; |