1:1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T28089	MPGES-1 Inhibitor-1		Prostaglandin Receptor
	mPGES-1 Inhibitor-1 is a novel selective inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1) with anti-inflammatory and analgesic activity for the study of acute liver injury.		Prostaglandin Receptor
T11580	Heme Oxygenase-1-IN-1	HO-1-IN-1	Reactive Oxygen Species
	Heme Oxygenase-1-IN-1 (HO-1-IN-1) is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM).		Reactive Oxygen Species
T13147	ICAM-1-IN-1		Integrin
	ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.		Integrin
T7888	Enpp-1-IN-1		PDE
	Enpp-1-IN-1 is an inhibitor of Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1)		PDE
TN2295	Vicenin-1	Vicenin -1	Antioxidant , Angiotensin-converting Enzyme (ACE)
	Vicenin-1 (Vicenin -1) is a flavonoid glycoside isolated from the seeds of the leguminous plant fenugreek with potent anti-inflammatory and antioxidant activity, inhibiting angiotensin-converting enzyme (ACE).		Antioxidant , Angiotensin-converting Enzyme (ACE)
T12910	Sigma-1 receptor antagonist 1		Sigma receptor
	Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor. Sigma-1 receptor antagonist 1 exhibits antineuropathic pain activity and can be used in the treatment of neuropathic pain studie...		Sigma receptor
T36432	A2ti-1		Virus Protease
	A2ti-1 is a highly selective inhibitor of annexin A2/S100A10 heterotetramer (A2t) (IC50: 24 μM) that inhibits ARV-mediated activation of Src and p38 mitogen-activated protein kinase (MAPK). A2ti-1 can be used to study hu...		Virus Protease
T3655	BMS-1	PD1-PDL1 inhibitor 1,PD-1/PD-L1 inhibitor 1	Apoptosis , PD-1/PD-L1
	BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene ...		Apoptosis , PD-1/PD-L1
T67928	NDH-1 inhibitor-1		Mitochondrial Metabolism
	NDH-1 inhibitor-1 is an effective NDH-1 inhibitor, which can inhibit bovine SMP (mitochondrial granules), potato SMP and Escherichia coli, with pI50 values of <4, 5.40, 6.15 µM, respectively.		Mitochondrial Metabolism
T9314	CC214-1		mTOR , Autophagy
	CC214-1 is an mTOR inhibitor with potential anticancer activity, inhibits protein translation, and induces autophagy. CC214-1 is an in vitro tool compound for exploring the biology of mTOR kinases and can be used to stud...		mTOR , Autophagy
T72064	TASK-1-IN-1		Potassium Channel
	TASK-1-IN-1 is a potent and selective inhibitor of TASK-1 (Potassium Channel) (IC50: 148 nM).TASK-1-IN-1 has a reduced inhibitory effect on the TASK-3 channel with an IC50 of 1750 nM.TASK-1-IN-1 has anticancer effects.		Potassium Channel
T7411	Rbin-1	Ribozinoindole-1	ATPase , Phosphatase
	Rbin-1 (Ribozinoindole-1) is a potent,specific inhibitor of eukaryotic ribosome biogenesis.		ATPase , Phosphatase
T23716	AMDE-1	AMDE 1	Autophagy
	AMDE-1 is an autophagy modulator and triggers autophagy in an Atg5-dependent manner. AMDE-1 recruits Atg16 to the pre-autophagosomal site and causes LC3 lipidation.		Autophagy
T77506	1-vinylpyrene	1-Ethenylpyrene	Others
	1-vinylpyrene (1-Ethenylpyrene) has antitumor activity and strongly inhibits the formation of skin tumors triggered by DMBA or B[]P in a dose-dependent manner and can be used to prevent tumor formation.		Others
T6500	Ferrostatin-1	Ferrostatin 1,Ferrostatin-1 (Fer-1)	Ferroptosis , Antifungal
	Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of iron death. Ferrostatin-1 potently inhibits Erastin-induced iron death in HT-1080 cells with an EC50 of 60 nM. Ferrostatin-1 also exhibits antioxidant and anti...		Ferroptosis , Antifungal
T4752	1-Aminocyclopropane-1-carboxylic acid	1-Aminocyclopropanecarboxylic acid,1-Amino-1-carboxycyclopropane,ACC	Endogenous Metabolite , NMDAR
	1-Aminocyclopropane-1-carboxylic acid (ACC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. It is a small molecul...		Endogenous Metabolite , NMDAR
T73585	PU.1-IN-1
	PU.1-IN-1 is a potent PU.1 inhibitor (IC50 : 2 nM) with anti-inflammatory activity.
T27093	CT-1	CT 1	p53
	CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.		p53
T8218	Vanin-1-IN-1	VUN34002	Others
	Vanin-1-IN-1 (VUN34002) is an vanin-1 enzyme inhibitor.		Others
T2651	IWR-1	IWR-1-endo,endo-IWR 1	Wnt/beta-catenin
	IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM).		Wnt/beta-catenin