Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 48.00 | |
2 mg | In stock | $ 70.00 | |
5 mg | In stock | $ 112.00 | |
10 mg | In stock | $ 187.00 | |
25 mg | In stock | $ 350.00 | |
50 mg | In stock | $ 503.00 | |
100 mg | In stock | $ 733.00 | |
500 mg | In stock | $ 1,530.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 118.00 |
Description | BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death. |
Targets&IC50 | PD-1/PD-L1 interaction:0.006 μM |
Synonyms | PD1-PDL1 inhibitor 1, PD-1/PD-L1 inhibitor 1 |
Molecular Weight | 475.58 |
Formula | C29H33NO5 |
CAS No. | 1675201-83-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 29 mg/mL (60.98 mM)
You can also refer to dose conversion for different animals. More
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BMS-1 1675201-83-8 Apoptosis Cell Cycle/Checkpoint Immunology/Inflammation PD-1/PD-L1 Inhibitor BMS 1 BMS1 PD1-PDL1 inhibitor 1 inhibit PD-1/PD-L1 inhibitor 1 inhibitor