Shopping Cart
- Remove All
- Your shopping cart is currently empty
IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $50 | In Stock | |
10 mg | $76 | In Stock | |
25 mg | $168 | In Stock | |
50 mg | $306 | In Stock | |
100 mg | $438 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM). |
Targets&IC50 | Wnt:0.2 μM(EC50) |
In vivo | In the Wnt pathway, IWR-1 interacts with Axin to exert a reversible inhibitory effect. |
Alias | IWR-1-endo, endo-IWR 1 |
Molecular Weight | 409.44 |
Formula | C25H19N3O3 |
Cas No. | 1127442-82-3 |
Smiles | O=C(Nc1cccc2cccnc12)c1ccc(cc1)N1C(=O)C2C3CC(C=C3)C2C1=O |
Relative Density. | 1.425 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 15 mg/mL (36.64 mM), Sonication is recommended. ![]() | |||||||||||||||||||||||||
In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4.09 mg/mL (9.99 mM), suspension.In vivo: Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.![]() | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.