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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11669 | IR415 | HBV | |
IR415 selectively interacts with Hepatitis B virus X protein (HBx, Kd = 2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBx protein on the activity of the dicer endoribonuclease. IR415 i... | |||
T16276 | NBD-556 | HIV Protease | |
NBD-556 is a small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding. | |||
T6515 | Go6976 | Gö 6976 | PKC |
Go6976 is a small molecule inhibitor of protein kinase C (PKC). Go6976 has been widely used in biomedical research as a tool to study the role of PKC in various physiological and pathophysiological processes. | |||
T5S0055 | Chelidonine | Helidonine,Khelidonin,Stylophorin | Apoptosis , Others , Influenza Virus |
1. Chelidonine (Stylophorin) isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways. 2. Chelidonine is a promising model ... | |||
T12399 | Peldesine | BCX 34 | Nucleoside Antimetabolite/Analog , HIV Protease |
Peldesine (BCX 34) is an effective, competitive, reversible, and orally active inhibitor of purine nucleoside phosphorylase. Peldesine inhibits T-cell proliferation with an IC50 of 800 nM. Peldesine can be used in resear... | |||
T0134 | Imiquimod | R 837,S-26308 | SARS-CoV , TLR , Autophagy , HSV |
Imiquimod (R 837) is an immune response modifier that acts as a toll-like receptor 7 agonist. | |||
T0994 | Ketotifen fumarate | HC 20511 fumarate | PDE , Histamine Receptor |
Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. | |||
T1602 | Valproic acid sodium salt | Sodium Valproate | Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , HDAC , Autophagy |
Valproic acid sodium salt (Sodium Valproate) is the sodium salt form of valproic acid with anti-epileptic activity. Valproic acid sodium salt is converted into its active form, valproate ion, in blood. Although the mecha... | |||
T6474 | Divalproex Sodium | Valproate semisodium,Epival | HDAC |
Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzyme... | |||
T7064 | Valproic Acid | Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid | Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy |
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research. | |||
T17190 | U18666A | Others , HCV Protease | |
U18666A is a cell-permeable drug and is a cholesterol synthesis and transport inhibitor. It inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus. | |||
T67854 | BAS 00489700 | Others | |
BAS 00489700 is a N-UTR interaction inhibitor. BAS 00489700 inhibits virus replication in cell culture. | |||
T8886 | NITD-2 | DNA/RNA Synthesis | |
NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in hu... | |||
T7366 | NGI-1 | ML414 | Virus Protease |
NGI-1 (ML414) is a a cell-permeable inhibitor of oligosaccharyltransferase (OST).can effectively reduce virus infectivity without affecting cell viability. | |||
T14304 | Aphidicolin | Others | |
Aphidicolin, an antibiotic derived from the mold Cephalosporium aphidicola, is a potent inhibitor of DNA (deoxyribonucleic acid) synthesis, effectively hindering the proliferation of herpes simplex virus[2]. It targets D... | |||
T1506 | Vidarabine | Adenine Arabinoside,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A | Nucleoside Antimetabolite/Analog , Tyrosine Kinases , DNA/RNA Synthesis , Antibiotic , HSV |
Vidarabine (Adenine Arabinoside) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and signific... | |||
TP1735L | Influenza HA 126-138 acetate | Influenza HA 126-138 acetate(207349-63-1 free base) | Others |
Influenza HA 126-138 acetate is a influenza virus hemagglutinin (HA) peptide acetate comprising amino acids 126-138. Influenza HA 126-138 acetate induces thymic and peripheral T-cell apoptosis. | |||
T26674 | AT-130 | AT 130 | HBV , DNA/RNA Synthesis |
AT-130 is a HBV virus inhibitor with improved potency (IC50 = 0.13 μM) and reduced toxicity in the HepAD38 cell line. AT-130 blocks HBV replication at the level of viral RNA packaging. | |||
TP1809 | TAT | HIV Protease | |
TAT peptide (YGRKKRRQRRR), originating from the human immunodeficiency virus-1 (HIV-1) transactivator of transcription (TAT), enhances the solubility and production of heterologous proteins[1]. This cell-penetrating pept... | |||
T12575 | Unesbulin | PTC596 | Apoptosis , BMI-1 |
Unesbulin (PTC596) is an orally active and selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1). |