Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Aphidicolin, an antibiotic derived from the mold Cephalosporium aphidicola, is a potent inhibitor of DNA (deoxyribonucleic acid) synthesis, effectively hindering the proliferation of herpes simplex virus[2]. It targets DNA polymerase α and δ, disrupting mitotic cell division by affecting DNA polymerase activity[1]. Additionally, aphidicolin enhances apoptosis when combined with arabinosyl nucleosides in a human promyelocytic leukemia cell line[3].
Pack Size | Availability | Price/USD | Quantity |
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1 mg | In stock | $ 123.00 |
Description | Aphidicolin, an antibiotic derived from the mold Cephalosporium aphidicola, is a potent inhibitor of DNA (deoxyribonucleic acid) synthesis, effectively hindering the proliferation of herpes simplex virus[2]. It targets DNA polymerase α and δ, disrupting mitotic cell division by affecting DNA polymerase activity[1]. Additionally, aphidicolin enhances apoptosis when combined with arabinosyl nucleosides in a human promyelocytic leukemia cell line[3]. |
Molecular Weight | 338.48 |
Formula | C20H34O4 |
CAS No. | 38966-21-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Aphidicolin 38966-21-1 Others inhibitor inhibit