lignans — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4S0792	Pinoresinol 4-O-β-D-glucopyranoside	(+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside	Others
	(+)-Pinoresinol-β-D-glucoside, also known as (+)-pinor, is a major active lignan furanoid found in Forsythia. It exhibits antioxidative, antihypertensive activities, and acts as an inhibitor of cyclic adenosine monophosp...		Others
TN2071	Picropodophyllone	(-)-Picropodophyllone,Picropodopyllotoxone	Others
	Picropodophyllone is one of the lignans from the roots of D. aurantiocaulis and D. pleianthum.		Others
T1121	Podofilox	Podophyllotoxin,(+)-Shikonin	Microtubule Associated , Topoisomerase
	Podofilox ((+)-Shikonin) is a lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irrit...		Microtubule Associated , Topoisomerase
TN1116	Schisandrone	Arisantetralone C	Beta Amyloid , NOS , NF-κB
	Schisandrone (Arisantetralone C) is a 4-aryltetrahydrofuran lignan extracted from the dried fruit of Schisandra chinensis.		Beta Amyloid , NOS , NF-κB
T3S0027	Picropodophyllotoxin	AXL 1717,Picropodophyllin	IGF-1R
	Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti...		IGF-1R
T3415	Secoisolariciresinol diglucoside	LGM2605	ROS
	Secoisolariciresinol diglucoside (LGM2605) was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage. Secoisolariciresinol diglucoside (25 mg/kg b.w.) exerts the antihyperglycemic effect ...		ROS
T5691	Paulownin		Anti-infection
	Paulownin, a furofuran lignan from Paulownia tomentosa,has the action of anti-inflammation,analgesia,immunity,hypoglycemia and has little toxicity.		Anti-infection
T5S2283	Sesamolin		p38 MAPK , Caspase , JNK
	1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 activation and ROS production. 3. Sesamolin and Sesamin can s...		p38 MAPK , Caspase , JNK
T5S0483	(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside	(-)-Syringaresnol-4-O-beta-D-apiofuranos	Others
	(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside ((-)-Syringaresnol-4-O-beta-D-apiofuranos) is a lignan glycosides from the bark of Albizzia myriophylla.		Others
TN3849	Dihydrodehydrodiconiferyl alcohol		TNF
	Dihydrodehydrodiconiferyl alcohol is the methanolic extract of Liriodendron tulipifera[1].		TNF
T4S1545	Licarin B	(-)-Licarin B,Licarine B	transporter , Antibacterial , PPAR
	1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity.		transporter , Antibacterial , PPAR
TN2197	Secoisolariciresinol		TNF
	Secoisolariciresinol is an enterolignan precursor, it has antioxidant, and estrogen-like activities, it can significantly suppress triglyceride (TG) accumulation in 3T3-L1 adipocytes.		TNF
TN2070	Picropodophyllol		Others
	Picropodophyllol is a natural product isolated from the roots of Dysosma versipellis		Others
TN1757	Hypophyllanthin		Potassium Channel , Calcium Channel , P-gp
	Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.		Potassium Channel , Calcium Channel , P-gp
TN2062	Phyllanthin		NF-κB
	Phyllanthin is widely used as hepatoprotective and antigenotoxic and inhibit function of P-gp.		NF-κB
TN6508	Trachelogenin	(-)-Trachelogenin	Virus Protease , c-Myc , HCV Protease , Wnt/beta-catenin
	Trachelogenin ((-)-Trachelogenin), isolated from Combretum fruticosum, is an HCV entry inhibitor with anti-proliferative effects. Its mechanism is related to affecting the phosphorylation of key proteins such as β-Cateni...		Virus Protease , c-Myc , HCV Protease , Wnt/beta-catenin
T3836	Eudesmin		MAPK , S6 Kinase
	Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 m...		MAPK , S6 Kinase
T8297	Gomisin N		Apoptosis
	Gomisin N, isolated from Schisandra chinensis, produces beneficial sedative and hypnotic bioactivity. It has the potential for use in the treatment of allergy and inhibits proliferation and induces apoptosis in cancer.		Apoptosis
TN4674	Nortrachelogenin-8'-O-beta-glucoside		Others
	Nortrachelogenin-8'-O-beta-glucoside is a lignan with a diarylhydroxybutyrolactone skeleton which isolated from the leaves and stems of Trachelospermum jasminoides (Lindl.) Lem.		Others
T8188	Podophyllotoxone		Others , Microtubule Associated
	Podophyllotoxinone, a natural compound found in Dysosma versipellis, shows inhibitory activity against L1210 leukemia and KB cells in vitro.		Others , Microtubule Associated