anti-stress — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2738	Dehydroandrographolide		NOS , Influenza Virus
	Dehydroandrographolide is a natural compound extracted from herbal medicine Andrographis paniculata (Burm f) Nees.		NOS , Influenza Virus
T2800	L-Theanine		Apoptosis , Others
	L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation.		Apoptosis , Others
T8678	Naphthazarin	5,8-Dihydroxy-1,4-naphthoquinone,DHNQ	Apoptosis
	Naphthazarin (5,8-Dihydroxy-1,4-naphthoquinone) is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, inter...		Apoptosis
T23550	YM-750	YM 750	Acyltransferase
	YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholest...		Acyltransferase
T2230	Paeoniflorin	Peoniflorin	HSP , COX
	Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.		HSP , COX
T6800	CCF642	AC1LYELL	Others
	CCF642 (AC1LYELL) is a novel PDI-inhibiting compound with antimyeloma activity.		Others
T21995	XAP044		GluR
	XAP044 is a mGlu7-selective antagonist which inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice with a half-maximal blockade at 88 nm[1].		GluR
TN1926	Methyl caffeate	Methyl caffeate acid	Others , Antibacterial
	Methyl caffeate (Methyl caffeate acid) acid		Others , Antibacterial
T2371	Emapunil	AC-5216,XBD-173	Others
	Emapunil (XBD-173) is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO.		Others
T8193	α-Thujone	Thujone,ALPHA-(-)-THUJONE	Apoptosis , Reactive Oxygen Species , GABA Receptor , AChR , Parasite , Autophagy
	α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
T3324	Lycorine	Galanthidine,Narcissine,Amarylline,Belamarine,Licorine	Apoptosis , Virus Protease , Antibacterial , AChR , Fatty Acid Synthase
	Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.
T2870	Matrine	Vegard,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine	Mitophagy , Ferroptosis , Opioid Receptor , Autophagy
	Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.		Mitophagy , Ferroptosis , Opioid Receptor , Autophagy
T3388	Calycosin-7-O-β-D-glucoside	calycosin-7-O-beta-D-glucopyranoside,Calycosin-7-O-beta-D-glucoside	MMP , Reactive Oxygen Species
	Calycosin-7-O-β-D-glucoside (calycosin-7-O-beta-D-glucopyranoside) possesses a protective effect on rat hepatocytes, an inhibitory effect on COX-2 activity. Calycosin 7-O-β-D-glucoside has antimicrobial activity. Calycos...		MMP , Reactive Oxygen Species
T10512	Prenyl-IN-1		Transferase
	Prenyl-IN-1 is a potent and selective prenylation inhibitor of geranylgeranyltransferase or farnesyltransferase.Prenyl-IN-1 shows anti-oxidative stress effects in a Parkinson's model. Prenyl-IN-1 showed anti-oxidative st...		Transferase
T4360	ML385		Others , Ferroptosis , Nrf2
	ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity. ML385 has anti-inflammatory activity by modulating anti-oxidative stress through the inhibition of NRF2. ML385 also exhibits anti-tumor activity.		Others , Ferroptosis , Nrf2
T3834	8-Epideoxyloganic acid		ROS , Immunology/Inflammation related
	8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during oxidative stress, the inhibition of ROS production, possibl...		ROS , Immunology/Inflammation related
T2S1008	Oxysophoridine	Sophoridine N-oxide	Apoptosis , Antioxidant
	Oxysophoridine (Sophoridine N-oxide) has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a potential neuroprotective agent for cerebral ischemia injury, ...		Apoptosis , Antioxidant
T22577	Antalarmin hydrochloride		CRFR , Immunology/Inflammation related
	Antalarmin hydrochloride is an antagonist of corticotropin-releasing factor 1(CRF1). Antalarmin hydrochloride produces anti-inflammatory effects and suppresses stress-induced gastric ulceration related to irritable bowel...		CRFR , Immunology/Inflammation related
TP1088	N-Acetylcarnosine	N-Acetyl-L-carnosine	Others
	N-Acetylcarnosine (N-Acetyl-L-carnosine) is thought to be able to combat some of the effects of oxidative stress as it has anti-oxidant properties.		Others
T31615	Elsibucol	AGI-1096,UNII-O7T92N1Y8T,AGI 1096	Antioxidant
	Elsibucol (AGI 1096) is a VCAM1 inhibitor for the study of organ transplant rejection.Elsibucol is a metabolically stable propanol derivative with antioxidant, anti-inflammatory and anti-proliferative properties. It lowe...		Antioxidant