Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 36.00 | |
50 mg | In stock | $ 53.00 | |
100 mg | In stock | $ 74.00 | |
200 mg | In stock | $ 119.00 | |
500 mg | In stock | $ 263.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 45.00 |
Description | Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist. |
In vitro | In mice, the median lethal dose (LD50) of Matrine administered via intraperitoneal injection is 157 mg/kg. |
In vivo | In human non-small cell lung cancer A549 and hepatocellular carcinoma SMMC-7721 cells, Matrine inhibits cell growth. Particularly, in A549 cells, Matrine induces apoptosis by reducing the Bcl-2 / Bax protein ratio. |
Source |
Synonyms | Vegard, Matridin-15-one, Matrinium, α-Matrine, (+)-Matrine |
Molecular Weight | 248.36 |
Formula | C15H24N2O |
CAS No. | 519-02-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 49 mg/mL (197.29 mM)
H2O: 11 mg/mL (44.29 mM), Heating is recommended.
DMSO: 49 mg/mL (197.29 mM)
You can also refer to dose conversion for different animals. More
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Matrine 519-02-8 Apoptosis Autophagy Endocrinology/Hormones GPCR/G Protein Neuroscience Opioid Receptor Mitophagy Ferroptosis Vegard Inhibitor Matridin-15-one anti-oxidative stress Mitochondrial Autophagy Matrinium α-Matrine alpha-Matrine A549 cells acute kidney injury (AKI) model Non-small cell lung cancer hepatoma (+)-Matrine inhibit a-Matrine inhibitor