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N-Acetylcarnosine

Catalog No. TP1088 CAS 56353-15-2

Synonyms: N-Acetyl-L-carnosine

N-Acetylcarnosine (N-Acetyl-L-carnosine) is thought to be able to combat some of the effects of oxidative stress as it has anti-oxidant properties.

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N-Acetylcarnosine, CAS 56353-15-2

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500 mg	In stock	$ 41.00

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Purity: 100%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	N-Acetylcarnosine (N-Acetyl-L-carnosine) is thought to be able to combat some of the effects of oxidative stress as it has anti-oxidant properties.
In vivo	Formulation A, containing 1% N-Acetylcarnosine, is administered in an 80 μL volume to the right eyes of male grey chinchilla rabbits (aged 3-4 months, weighing 2-3 k). This N-Acetylcarnosine prodrug in eye drop form is designed to enhance clinical outcomes for ophthalmic conditions, specifically aiding in the prevention and reversal of cataracts in both human and animal eyes [1].

Synonyms	N-Acetyl-L-carnosine
Molecular Weight	268.27
Formula	C11H16N4O4
CAS No.	56353-15-2

Storage

store at low temperature,keep away from moisture,keep away from direct sunlight

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 250 mg/mL (931.90 mM), Sonication is recommended.

References and Literature

1. Babizhayev MA, et al. N-Acetylcarnosine, a natural histidine-containing dipeptide, as a potent ophthalmic drug in treatment of human cataracts. Peptides. 2001 Jun;22(6):979-94.

Citations

1. Ma X, Tan X, Yu B, et al. DOCK2 regulates antifungal immunity by regulating RAC GTPase activity. Cellular & Molecular Immunology. 2022: 1-17. 2. Xue K H, Jiang Y F, Bai J Y, et al.Melatonin suppresses Akt/mTOR/S6K activity, induces cell apoptosis, and synergistically inhibits cell growth with sunitinib in renal carcinoma cells via reversing Warburg effect.Redox Report.2023, 28(1): 2251234.

Related compound libraries

This product is contained In the following compound libraries：

Human Metabolite Library Oxidation-Reduction Compound Library ReFRAME Related Library NO PAINS Compound Library Human Endogenous Metabolite Compound Library Plus

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

N-Acetylcarnosine 56353-15-2 Others histidine-containing NAcetylcarnosine Inhibitor L-carnosine pharmacological cataracts dipeptide N Acetylcarnosine inhibit principal drug ophthalmic N-Acetyl-L-carnosine inhibitor

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