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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3587 | NOD-IN-1 | Compound 4 | NOD-like Receptor (NLR) , NOD |
NOD-IN-1 (Compound 4) is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors. | |||
T6S1256 | Ruscogenin | NOS , NF-κB , NOD-like Receptor (NLR) | |
1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein ... | |||
T15052 | Dapansutrile | NOD-like Receptor (NLR) , NOD | |
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity. | |||
T13375 | YQ128 | IL Receptor , NOD-like Receptor (NLR) , NOD , Interleukin | |
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity. | |||
T0772 | Troxerutin | Trihydroxyethylrutin | NOD-like Receptor (NLR) |
Troxerutin (Trihydroxyethylrutin), a natural bioflavonoid, is isolated from Sophora japonica. It has many benefits and medicinal properties. | |||
T4217 | INF39 | NOD-like Receptor (NLR) , NOD | |
INF39 is a noncytotoxic and irreversible NLRP3 inhibitor. | |||
T4164 | CY-09 | CY 09 | NOD-like Receptor (NLR) , NOD |
CY-09 is an NLRP3 inhibitor. | |||
T8828 | CP 424174 | IL Receptor | |
CP 424174 is an inhibitor of IL-1β post-translational processing with IC50 of 210 nM. Inhibits the formation of mature IL-1β. Indirectly inhibits NLRP3. Active in vivo and orally bioavailable. | |||
TQ0165 | Arglabin | (+)-Arglabin | NOD-like Receptor (NLR) , Transferase , NOD , Autophagy |
Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects. | |||
T9222 | Emlenoflast | MCC7840 | NOD-like Receptor (NLR) , NOD |
Emlenoflast (MCC7840) is a selective inhibitor of NLRP3 inflammasome. | |||
T16159 | Muramyl dipeptide | MDP | NOD |
Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide indirectly decreases osteoclast differentiation... | |||
T38361 | GSK717 | IL Receptor , NOD | |
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretio... | |||
T3701 | MCC950 | CP-456773 | NOD |
CP-456773 (MCC950 (CP-456773) and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and caspase 1 processing. MCC950 blocked canonical and... | |||
T4S0350 | Licochalcone B | Beta Amyloid , Others | |
1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. 2. LCB and Licoc... | |||
T6591 | Nodinitib-1 | ML130,CID-1088438 | TNF , NOD-like Receptor (NLR) , NOD |
Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM. | |||
T3092 | Nigericin sodium salt | Potassium Channel , NOD-like Receptor (NLR) , Antibacterial , Antibiotic , NOD | |
Nigericin sodium salt is an antibiotic, an NLRP3 activator, and a cationic ion carrier. Nigericin sodium triggers the activation of the NALP3 inflammasome, which inhibits Golgi function and suppresses the growth of Gram-... | |||
T6454 | CORM-3 | CORM3 | Others , NF-κB , NOD-like Receptor (NLR) |
CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity. | |||
T28178 | NLRP3-IN-9 | INF-4E,INF 4E,INF4E | NOD |
NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- ... | |||
T1404 | Stavudine | d4T,Sanilvudine,BMY-27857,NSC 163661 | Apoptosis , Nucleoside Antimetabolite/Analog , HIV Protease , NOD-like Receptor (NLR) , Reverse Transcriptase , Autophagy |
Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV. | |||
T2893 | Muscone | 3-Methylcyclopentadecanone,Methylexaltone | MMP , TNF , NF-κB , NOD-like Receptor (NLR) , P-gp , Interleukin |
Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk. |