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Emlenoflast

Catalog No. T9222 CAS 1995067-59-8

Synonyms: MCC7840

Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Emlenoflast, CAS 1995067-59-8

Pack Size	Availability	Price/USD	Quantity
1 mg	5 days	$ 116.00
5 mg	5 days	$ 315.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Emlenoflast is a potent and selective inhibitor of NLRP3 inflammasome.
Targets&IC50	NLRP3:< 100 nM

Synonyms	MCC7840
Molecular Weight	388.48
Formula	C19H24N4O3S
CAS No.	1995067-59-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. El-Sharkawy LY, et, al. Inhibiting the NLRP3 Inflammasome. Molecules. 2020 Nov 25;25(23):5533. 2. O'neill L, et, al. Sulfonylureas and related compounds and use of same. WO2016131098A1.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Anti-Prostate Cancer Compound Library Bioactive Compounds Library Max Pyroptosis Compound Library Bioactive Compound Library

Related Products

Related compounds with same targets

Emlenoflast sodium MCC950 Nodinitib-1 BMS986299 INF39 NLRP3-IN-10 7,4'-Dihydroxyflavone NOD-IN-1

Dose Conversion

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Emlenoflast 1995067-59-8 Immunology/Inflammation NF-Κb NOD NOD-like Receptor (NLR) MCC7840 MCC 7840 sulfonylurea NLRP3 inhibit MCC-7840 inflammatory inflammasome Inhibitor inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.