Powder: -20°C for 3 years
In solvent: -80°C for 2 years
CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.
Description | CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity. |
In vitro | CORM-3 protects against hypoxia-reoxygenation and oxidative stress by promoting CO release in cardiac cells. [1] CORM-3 attenuates the inflammatory response induced by LPS in RAW264.7 murine macrophages. [2] CORM-3 also uncouples mitochondrial respiration via interaction with the phosphate carrier. [4] |
In vivo | CORM-3 (40 mg/kg i.p.) prolongs the survival of murine cardiac grafts and attenuates organ rejection in CBA mice transplanted with BALB/c hearts. [1] CORM-3 (20 mg/kg i.p.) decreases cellular infiltration, joint inflammation and destruction in a collagen-induced arthritis mouse model. [3] |
Synonyms | CORM 3, (OC-6-44)-三羰基氯(甘氨酸基)钌, CORM3 |
Molecular Weight | 294.61 |
Formula | C5H4ClNO5Ru |
CAS No. | 475473-26-8 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 129 mM
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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CORM-3 475473-26-8 NF-Kb信号通路 免疫与炎症 其他 NF-κB NOD-like Receptor (NLR) Others inhibit Inhibitor CORM3 Nuclear factor-kappaB Nuclear factor-κB CORM 3 inhibitor