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CORM-3
🥰Excellent
Catalog No. T6454Cas No. 475473-26-8
Alias CORM3
CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.
CORM-3
🥰Excellent
Purity: 98%
Catalog No. T6454Alias CORM3Cas No. 475473-26-8
CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $30 | In Stock | |
| 10 mg | $51 | In Stock | |
| 25 mg | $84 | In Stock | |
| 50 mg | $123 | In Stock | |
| 100 mg | $182 | In Stock | |
| 500 mg | $457 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $53 | In Stock |
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Purity:98%
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Product Introduction
Bioactivity
Chemical Properties
| Description | CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity. |
| In vitro | CORM-3 protects against hypoxia-reoxygenation and oxidative stress by promoting CO release in cardiac cells. [1] CORM-3 attenuates the inflammatory response induced by LPS in RAW264.7 murine macrophages. [2] CORM-3 also uncouples mitochondrial respiration via interaction with the phosphate carrier. [4] |
| In vivo | CORM-3 (40 mg/kg i.p.) prolongs the survival of murine cardiac grafts and attenuates organ rejection in CBA mice transplanted with BALB/c hearts. [1] CORM-3 (20 mg/kg i.p.) decreases cellular infiltration, joint inflammation and destruction in a collagen-induced arthritis mouse model. [3] |
| Alias | CORM3 |
| Molecular Weight | 294.61 |
| Formula | C5H4ClNO5Ru |
| Cas No. | 475473-26-8 |
| Smiles | C(#O)[Ru+2]1(C#O)(C#O)([Cl-])[O-]C(=O)C[NH2]1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (169.72 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Sci Citations
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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