store at low temperature,store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 30.00 | |
10 mg | In stock | $ 51.00 | |
25 mg | In stock | $ 84.00 | |
50 mg | In stock | $ 123.00 | |
100 mg | In stock | $ 182.00 | |
500 mg | In stock | $ 457.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 53.00 |
Description | CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity. |
In vitro | CORM-3 protects against hypoxia-reoxygenation and oxidative stress by promoting CO release in cardiac cells. [1] CORM-3 attenuates the inflammatory response induced by LPS in RAW264.7 murine macrophages. [2] CORM-3 also uncouples mitochondrial respiration via interaction with the phosphate carrier. [4] |
In vivo | CORM-3 (40 mg/kg i.p.) prolongs the survival of murine cardiac grafts and attenuates organ rejection in CBA mice transplanted with BALB/c hearts. [1] CORM-3 (20 mg/kg i.p.) decreases cellular infiltration, joint inflammation and destruction in a collagen-induced arthritis mouse model. [3] |
Synonyms | CORM3 |
Molecular Weight | 294.61 |
Formula | C5H4ClNO5Ru |
CAS No. | 475473-26-8 |
store at low temperature,store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 129 mM
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CORM-3 475473-26-8 Immunology/Inflammation NF-Κb Others NOD-like Receptor (NLR) NF-κB inhibit Inhibitor CORM 3 Nuclear factor-kappaB Nuclear factor-κB CORM3 inhibitor