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CORM-3

CORM-3
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CORM-3

Catalog No. T6454Cas No. 475473-26-8
CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
5 mg$30In Stock
10 mg$51In Stock
25 mg$84In Stock
50 mg$123In Stock
100 mg$182In Stock
500 mg$457In Stock
1 mL x 10 mM (in DMSO)$53In Stock
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Product Introduction

Bioactivity
Description
CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.
In vitro
CORM-3 protects against hypoxia-reoxygenation and oxidative stress by promoting CO release in cardiac cells. [1] CORM-3 attenuates the inflammatory response induced by LPS in RAW264.7 murine macrophages. [2] CORM-3 also uncouples mitochondrial respiration via interaction with the phosphate carrier. [4]
In vivo
CORM-3 (40 mg/kg i.p.) prolongs the survival of murine cardiac grafts and attenuates organ rejection in CBA mice transplanted with BALB/c hearts. [1] CORM-3 (20 mg/kg i.p.) decreases cellular infiltration, joint inflammation and destruction in a collagen-induced arthritis mouse model. [3]
AliasCORM3
Chemical Properties
Molecular Weight294.61
FormulaC5H4ClNO5Ru
Cas No.475473-26-8
Storage & Solubility Information
Storagestore at low temperature,store under nitrogen Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 50 mg/mL (169.72 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3943 mL16.9716 mL33.9432 mL169.7159 mL
5 mM0.6789 mL3.3943 mL6.7886 mL33.9432 mL
10 mM0.3394 mL1.6972 mL3.3943 mL16.9716 mL
20 mM0.1697 mL0.8486 mL1.6972 mL8.4858 mL
50 mM0.0679 mL0.3394 mL0.6789 mL3.3943 mL
100 mM0.0339 mL0.1697 mL0.3394 mL1.6972 mL

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