k( ) — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T11742	K-7174		IL Receptor , TNF
	K-7174 is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-α.		IL Receptor , TNF
T5S2309	Hosenkoside K	(+)-Hosenkoside K	Others
	Hosenkoside K ((+)-Hosenkoside K) is a baccharane glycoside found in the seeds of impatiens balsamina.		Others
T8936	Proteinase K	proteinase K for tritirachium album,Protease K	Others
	Proteinase K (proteinase K for tritirachium album) is a nonspecific serine protease that is useful for general digestion of proteins. It is active in the presence of SDS or urea and over a wide range of pH (4-12), salt c...		Others
T24240	K-8012	K8012,K 8012	Retinoid Receptor , RAR/RXR
	K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.		Retinoid Receptor , RAR/RXR
T9954	K-975		Others
	K-975 is a highly selective, orally active TEAD inhibitor, effectively inhibiting protein-protein interactions between TEAD and YAP1/TAZ.		Others
T19603	Vitamin K	Kephton,Vitamin K1(20)	Endogenous Metabolite
	Vitamin K (Kephton) has blood coagulation action and is important for coagulation factors, matrix-Gla protein, and osteocalcin.		Endogenous Metabolite
T8200	Ginkgolide K		AMPK , Autophagy
	Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.		AMPK , Autophagy
T15639	K-756		PARP , Wnt/beta-catenin
	K-756 is a direct and selective inhibitor of tankyrase (TNKS), which inhibits the ADP-ribosylation activity of TNKS1 and TNKS2 (IC50s: 31 and 36 nM, respectively).		PARP , Wnt/beta-catenin
T11733	K-604 dihydrochloride		Acyltransferase
	K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 inhibitor with an IC50 of 0.45±0.06 μM.		Acyltransferase
T3811	Ginsenoside C-K	Ginsenoside compound K,Ginsenoside K	P450 , cell cycle arrest , COX , NO Synthase
	Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.		P450 , cell cycle arrest , COX , NO Synthase
T11734	K-80003	TX-803	Akt , RAR/RXR
	K-80003(TX-803) is a potent retinol-like X-receptor-alpha regulator that inhibits TRxrα-dependent Akt activation and tumor cell growth.		Akt , RAR/RXR
TP2009L	K 41498 aceate		CRFR
	K41498 acetate, an analogues of antisauvagine-30 (aSvg-30), inhibits sauvagine-stimulated cAMP accumulation in hCRF2α- and hCRF2β-expressing cells. K41498 acetate is a potent and highly selective antagonist CRF2 receptor...		CRFR
TQ0144	(S)-(-)-Bay-K-8644	(S)-(-)-Bay K 8644	Calcium Channel
	(S)-(-)-Bay-K-8644 ((S)-(-)-Bay K 8644) is an agonist of L-type Ca2+ channel and activates Ba2+ currents with an EC50 of 32 nM.		Calcium Channel
T6777	Bay K 8644	(±)-BAY-K-8644,SQ 28,873	Calcium Channel
	Bay K 8644 (SQ 28,873) is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM.		Calcium Channel
TQ0145	(R)-(+)-Bay-K-8644	(R)-(+)-Bay K 8644	Calcium Channel , PPAR
	(R)-(+)-Bay-K-8644 is a Ca2+ channel agonist, a dihydropyridine agonist that inhibits Ba2+ currents (IBa), induces central respiratory depression in cats, and inhibits platelet activation through competitive antagonism o...		Calcium Channel , PPAR
T5469	K-Ras-IN-1		Raf , Ras
	K-Ras-IN-1 is a K-Ras inhibitor.		Raf , Ras
T29087	VA-K-14 hydrochloride	VAK14 Hydrochloride,VA K 14 HCl,VA-K-14 HCl,VAK14 HCl	TSH Receptor
	VA-K-14 hydrochloride（VAK14 HCl） is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogate...		TSH Receptor
T1914	K02288	K 02288	ALK , TGF-beta/Smad
	K 02288 is a novel small molecule inhibitor of ALK1/2/3/6.		ALK , TGF-beta/Smad
T6555	K-Ras(G12C) inhibitor 12		Apoptosis , Raf , Ras
	K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).		Apoptosis , Raf , Ras
T4618	BGG463	K 0859	Bcr-Abl , CDK
	BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with a 50% inhibitory concentration (IC50) of 0.25 μM, 0.09 μM and 0.590 μM, respectively.		Bcr-Abl , CDK