Powder: -20°C for 3 years | In solvent: -80°C for 1 year
K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 48.00 | |
2 mg | In stock | $ 68.00 | |
5 mg | In stock | $ 117.00 | |
10 mg | In stock | $ 197.00 | |
25 mg | In stock | $ 328.00 | |
50 mg | In stock | $ 489.00 | |
100 mg | In stock | $ 713.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 128.00 |
Description | K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C). |
In vitro | K-Ras(G12C) inhibitor 12 belongs to a series of small molecules, which irreversibly bind to a common oncogenic mutant K-Ras(G12C) and blocks K-Ras(G12C) interactions. Some of them decrease viability and increase apoptosis of G12C-containing cancer cell lines. [1] |
Molecular Weight | 449.67 |
Formula | C15H17ClIN3O3 |
CAS No. | 1469337-95-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 26 mg/mL (57.8 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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K-Ras(G12C) inhibitor 12 1469337-95-8 Apoptosis GPCR/G Protein MAPK Raf Ras K-Ras(G-12C) inhibitor 12 inhibit Inhibitor KRas(G12C) inhibitor 12 K Ras(G12C) inhibitor 12 inhibitor