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K-8012

Name: K-8012
Brand: TargetMol
SKU: T24240
Price: 117 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T24240Cas No. 1346513-17-4

Alias K8012, K 8012

K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.

K-8012

🥰Excellent

Purity: 99.72%

Catalog No. T24240Alias K8012, K 8012Cas No. 1346513-17-4

K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.

Pack Size	Price	Availability
1 mg	$117	In Stock
5 mg	$268	In Stock
10 mg	$395	In Stock
25 mg	$592	In Stock
50 mg	$828	In Stock
100 mg	$1,130	In Stock
500 mg	$2,270	In Stock
1 mL x 10 mM (in DMSO)	$281	In Stock

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.72%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.
Synonyms	K8012, K 8012

Chemical Properties

Molecular Weight	374.45
Formula	C₂₃H₂₃FN₄
Cas No.	1346513-17-4
Smiles	C(=C/1\C=2C(C(CCC=3NN=NN3)=C1C)=CC(F)=CC2)\C4=CC=C(C(C)C)C=C4
Relative Density.	1.223 g/cm3 (Predicted)
Color	Orange
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (160.24 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6706 mL	13.3529 mL	26.7058 mL	133.5292 mL
5 mM	0.5341 mL	2.6706 mL	5.3412 mL	26.7058 mL
10 mM	0.2671 mL	1.3353 mL	2.6706 mL	13.3529 mL
20 mM	0.1335 mL	0.6676 mL	1.3353 mL	6.6765 mL
50 mM	0.0534 mL	0.2671 mL	0.5341 mL	2.6706 mL
100 mM	0.0267 mL	0.1335 mL	0.2671 mL	1.3353 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc