Search Result

Search Results for " fas 1 "

Targets

Compounds

Natural Products

1738

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T11266L	FAS-IN-1 Tosylate		Fatty Acid Synthase
	FAS-IN-1 Tosylate is an effective fatty acid synthase inhibitor;Has an IC50 of 10 nM.		Fatty Acid Synthase
T11266	FASN-IN-4	FAS-IN-1	Others
	FAS-IN-1 is a potent inhibitor of Fatty acid synthase (FAS) wtih IC50 of 10 nM.		Others
T21724L	Fas C-Terminal Tripeptide Acetate	Fas C-Terminal Tripeptide Acetate (189109-90-8 free base)	Others , Fatty Acid Synthase
	Fas C-Terminal Tripeptide Acetate shows inhibitory activity of Fas/FAP-1 binding.		Others , Fatty Acid Synthase
TQ0220	KR-33493	KR-33494,KM-819	Fas/FasL
	KR-33493 is a FAS-associated factor 1 (FAF1) inhibitor and can be used in studies about Parkinson's disease.		Fas/FasL
T8616	Fasentin	N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide	transporter
	Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) is an inhibitor of GluT1.		transporter
T80442	Fasciculin-II	Fas-2
	Fasciculin-II (Fas-2) acts as a potential inhibitor of acetylcholinesterase (AChE) [1].
T14570	BI 99179	BI99179	Fatty Acid Synthase
	BI99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC50 of 79 nM and it exhibits significant exposure (both peripheral and central) upon oral administration in rats[1].		Fatty Acid Synthase
T60851	Apoptotic agent-1		Others
	Apoptotic agent-1 (Compound 8a) induces Fas receptor and Cyto C genes over-expression that is an apoptotic agent with high antiproliferative activity against cancer cells as well as low cytotoxic effect [1].		Others
T36331	Z-AEVD-FMK	Z-AEVD-FMK,Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone	Others
	Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.[1] At 10 &#181M, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its activ...		Others
T78586	Ac-IETD-CHO		Apoptosis
	Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure. Furthermore, this compound hampers cell death induced by cy...		Apoptosis
T60266	(Rac)-Indoximod		Others
	(Rac)-Indoximod (1-Methyl-DL-tryptophan) is a potent inhibitor of indoleamine 2,3-dioxygenase (IDO). Combined treatment with IFN-γ and (Rac)-Indoximod significantly suppresses the activity of α-SMA-expressing human cardi...		Others
T64171	LXR antagonist 2		Others
	LXR antagonist 2 (compound 10rr) is a potent LXR (liver X receptor) inverse agonist, acting on LXRβ (IC50: 0.36 μM) and LXRα (IC50: 2.25 μM). LXR antagonist 2 is an adipogenesis inhibitor that downregulates LXR target ge...		Others
T76393	Amyloid 17-42
	Amyloid 17-42 (Aβ(17-42)), a significant component of diffuse plaques in Alzheimer's disease and cerebellar pre-amyloid in Down's syndrome, results from the alpha- and gamma-secretase cleavage of amyloid precursor protei...
T36130	22(S)-hydroxy Cholesterol	22(S)-hydroxy Cholesterol,22β-hydroxy Cholesterol	Others
	22(S)-hydroxy Cholesterol is a synthetic oxysterol and a modulator of the liver X receptor (LXR). [1] t prevents monocyte chemoattractant protein 1 (MCP-1) expression induced by the LXR agonist GW 3965 in primary hepatoc...		Others

Compounds

FAS-IN-1 Tosylate

T11266L

Synonym:

Target: Fatty Acid Synthase

Fas C-Terminal Tripeptide Acetate

T21724L

Synonym: Fas C-Terminal Tripeptide Acetate (189109-90-8 free base)

Target: Others, Fatty Acid Synthase

KR-33493

TQ0220

Synonym: KR-33494,KM-819

Target: Fas/FasL

Fasentin

T8616

Synonym: N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide

Target: Fatty Acid Synthase

Synonym: Z-AEVD-FMK,Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone

22(S)-hydroxy Cholesterol

T36130

Synonym: 22(S)-hydroxy Cholesterol,22β-hydroxy Cholesterol

Target: Others

Cat No.	Product Name	Synonyms	Targets
TJS0387	Desoxyrhaponticin	Deoxyrhapontin,Deoxyrhaponticin	Apoptosis , Fatty Acid Synthase
	1. Desoxyrhaponticin (Deoxyrhaponticin) is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least...		Apoptosis , Fatty Acid Synthase
T3S1775	Tectochrysin	NSC 80687,Techtochrysine,Techtochrysin	NF-κB , STAT
	1. Tectochrysin (Techtochrysine) has antioxidant effect. 2. Tectochrysin is promising inhibitors for the reversal of ABCG2-mediated drug transport. 3. Tectochrysin leads to apoptotic cell death in NSC-LC cells through ac...		NF-κB , STAT

Natural Products

Desoxyrhaponticin

TJS0387

Synonym: Deoxyrhapontin,Deoxyrhaponticin

Target: Apoptosis, Fatty Acid Synthase

Tectochrysin

T3S1775

Synonym: NSC 80687,Techtochrysine,Techtochrysin

Target: NF-κB, STAT

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01704	Fas/CD95 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Fas/CD95 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.2 kDa and the accession number is P25445-1.
TMPY-00799	Fas/CD95 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Fas/CD95 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.4 kDa and the accession number is P25445-1.
TMPJ-00215	Fas/CD95 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNF receptor superfamily and is designated TNFRSF6. Mouse Fas contains 1 death domain and 3 TNFR-Cys repeats. It detected...
TMPY-01426	Fas/CD95 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Fas/CD95 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is P25446.
TMPY-03956	Fas Ligand Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells su...
TMPJ-00696	NOL3 Protein, Human, Recombinant	Human	E. coli
	Nucleolar protein 3 is encoded by NOL3 gene. Multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in...
TMPY-02597	IL-37 Protein, Human, Recombinant	Human	E. coli
	Interleukin 1 family member 7, or interleukin 37 (IL1F7 / IL37 / IL-1H4) is a secretory protein belonging to the Interleukin 1 family. IL-1F7 was localized in human peripheral monocytic cells. It has been localized the e...
TMPY-02578	DKKL1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Dickkopf-like 1 (DKKL1) or soggy 1, is a glycoprotein unique to mammals that is expressed primarily in developing spermatocytes and localized in the acrosome of mature sperm. It is also expressed in the trophectoderm / p...
TMPY-02213	RAIDD Protein, Human, Recombinant (His)	Human	E. coli
	Death domain-containing protein CRADD, also known as Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD and RAIDD, is a protein which is constitutively expressed in most tissu...
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&...
TMPY-03745	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-02335	OSMR Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	OSMR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 83.7 kDa and the accession number is O70458-1.
TMPY-02112	FGFR4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	FGFR4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22455-1.
TMPY-01920	BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)	Human	HEK293 Cells
	BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9Y275-1.
TMPY-01053	Prolactin Receptor Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Prolactin Receptor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is P16471-1.
TMPY-01349	ICAM-1/CD54 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	ICAM-1/CD54 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.7 kDa and the accession number is P13597-1.
TMPY-00820	IgG1 Fc Protein, Human, Recombinant (C103S)	Human	HEK293 Cells
	IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPY-00742	EGFR Protein, Human, Recombinant (His)	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.8 kDa and the accession number is P00533-1.
TMPY-02603	STAT6 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6...
TMPY-01003	TCN2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	TCN2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.7 kDa and the accession number is P20062-1.
TMPY-06873	FLT3 Ligand Protein, Human, Recombinant	Human	E. coli
	FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-01968	CD32A Protein, Human, Recombinant (167 His, His)	Human	HEK293 Cells
	CD32A Protein, Human, Recombinant (167 His, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P12318-1.
TMPY-01395	CTHRC1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CTHRC1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.5 kDa and the accession number is Q96CG8-1.
TMPY-01389	HER3/ERBB3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	HER3/ERBB3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.2 kDa and the accession number is P21860-1.
TMPY-01813	ACRV1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the a...
TMPY-02700	BCL2 Protein, Human, Recombinant (His)	Human	E. coli
	BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family a...
TMPY-05840	IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.56 kDa and the accession number is P59822-1.
TMPY-04104	LIF Protein, Human, Recombinant	Human	HEK293 Cells
	LIF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.7 kDa and the accession number is P15018-1.
TMPY-04939	LAG-3 Protein, Human, Recombinant	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-00925	SOST Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SOST Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is Q9BQB4-1.
TMPY-02062	SULT1A1 Protein, Human, Recombinant (His)	Human	E. coli
	Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroid...
TMPY-03782	Albumin Protein, Human, Recombinant	Human	P. pastoris (Yeast)
	Albumin Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 66.4 kDa and the accession number is P02768-1.
TMPY-00843	IL-25/IL17E Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-25/IL17E Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45 kDa and the accession number is Q9H293-1.
TMPY-04153	RNF43 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expr...
TMPY-01209	IL-7R alpha/CD127 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-7R alpha/CD127 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P16871-1.
TMPY-05566	Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)	Human	HEK293 Cells
	Siglec-2/CD22 Protein, Human, Recombinant (His, Solution) is expressed in HEK293 mammalian cells with His tag. The accession number is P20273-1.
TMPY-01137	HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)	Human	HEK293 Cells
	HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P04626-1.
TMPY-05593	IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 42.4 kDa and the accession number is Q9NPH3-1.
TMPY-00835	IGFBP-3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IGFBP-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is P17936-1.
TMPY-04824	CTLA-4 Protein, Human, Recombinant	Human	HEK293 Cells
	CTLA-4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.5 kDa and the accession number is P16410-1.
TMPY-01062	EGF Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	EGF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33 kDa and the accession number is P01133-1.
TMPY-00686	Complement C2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Complement C2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.5 kDa and the accession number is P06681-1.
TMPY-01934	IL-21R Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-21R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is Q9HBE5-1.
TMPY-01145	NKp30/NCR3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	NKp30/NCR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.4 kDa and the accession number is O14931-1.
TMPY-00694	Carbonic Anhydrase 12 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Carbonic Anhydrase 12 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is O43570-1.
TMPY-02141	UPAR/PLAUR Protein, Human, Recombinant (His)	Human	HEK293 Cells
	uPAR/PLAUR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.8 kDa and the accession number is Q03405-1.
TMPY-01076	Gp130/IL6ST Protein, Human, Recombinant (His & hFc)	Human	HEK293 Cells
	gp130/IL6ST Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 96 kDa and the accession number is P40189-1.
TMPY-01139	PDGFRA Protein, Human, Recombinant (His)	Human	HEK293 Cells
	PDGFRA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is P16234-1.
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