etu — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T20110	Ethylene thiourea	ETU,Imidazolidinethione,NCI C03372,NCIC03372,NCI-C03372	Others
	Ethylene thiourea (NCIC03372) is a pesticide used in fruit and vegetable production. Ethylene thiourea is also used as a novel contrast agent for MRI studies based on proton chemical exchange-dependent saturation transfe...		Others
TN2148	Retusin	5-Hydroxy-3,7,3',4'-tetramethoxyflavone,Quercetin-3,7,3',4'-tetramethyl ether	ATPase , Free radical scavengers , Tyrosinase
	Retusin is derived from the leaves of Talinum triangulare. Retusin Retusin can be used in studies about acting as pre- and postemergent herbicides.		ATPase , Free radical scavengers , Tyrosinase
T14524	Befetupitant	Ro67-5930	Neurokinin receptor
	Befetupitant (Ro67-5930) is a potent and selective tachykinin 1 receptor (NK1R) antagonist for the study of corneal neovascularization.		Neurokinin receptor
T8594	Pheneturide	2-PHENYLBUTYRYLUREA,S-46,Benuride	Others
	Pheneturide (Benuride) is the ureide class, used to treat epilepsy, and is an anticonvulsant.		Others
T9905	Cetuximab	Cetuximab (anti-EGFR),C225	EGFR
	Cetuximab (C225) is a monoclonal antibody that is an inhibitor of human epidermal growth factor receptor (EGFR) (Kd=0.201 nM). Cetuximab has antitumor activity, inhibiting tumor cell proliferation and inducing apoptosis.		EGFR
T76857	Anetumab		Others
	Anetumab is a novel fully human anti-mesothelin IgG1 antibody that is a naked antibody to Anetumab ravtansine.Anetumab can be used to synthesize the antibody-activated molecule coupling, Anetumab ravtansine.Anetumab can ...		Others
T3S2152	23-Hydroxybetulinic acid	Anemosapogenin	Others
	23-Hydroxybetulinic acid (Anemosapogenin) shows potent anti-tumor effect in vivo, but it has some toxicity, structure modification should be needed.		Others
T76766	Mirvetuximab	M9346A	Antifolate
	Mirvetuximab (M9346A) is a novel folate receptor α (FRα) monoclonal antibody targeting anti-FOLR1 (folate receptor 1). Mirvetuximab soravtansine is often conjugated with platinum compounds or other compounds to form anti...		Antifolate
T9901A-005	Zolbetuximab	IMAB362	Others
	Zolbetuximab(IMAB362) is a monoclonal antibody that specifically targets Claudin-18.2.Zolbetuximab has potential antitumor activity, mediating killing of Claudin-18.2-positive cells through an immune effector mechanism.Z...		Others
T6905	Netupitant	Ro 67-31898/000,CID 6451149	Neurokinin receptor
	Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM).		Neurokinin receptor
T1145	Diminazene Aceturate		Others , Serine Protease , Parasite
	Diminazene is a trypanocidal agent.		Others , Serine Protease , Parasite
T2830	Betulinic acid	ALS-357,Lupatic acid,Betulic acid	Apoptosis , Mitophagy , NF-κB , HIV Protease , Topoisomerase , Endogenous Metabolite , Aminopeptidase , Autophagy
	Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial, and anti-inflammatory propert...
T5S0018	Betulonic acid	(+)-Betulonic acid,Betunolic acid,Liquidambaric acid	Parasite , HSV
	1. Betulonic acid (Liquidambaric acid) amide stimulated the regenerative response in hepatocytes under conditions of combined toxic exposure and promoted recovery of their qualitative and quantitative characteristics, wh...		Parasite , HSV
T3121	Betulin	Trochol,betulinic alcohol,betuline,betulinol,Betulol	Apoptosis , Endogenous Metabolite , Lipid , Fatty Acid Synthase
	Betulin (betulinol) (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene. It is commonly isolated from the bark of birch trees where it forms up to 30% of the dry weight of the extractive and is fo...
T2S0765	Epibetulinic acid		NO Synthase , Prostaglandin Receptor
	Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin.		NO Synthase , Prostaglandin Receptor
T77362	Vorsetuzumab	SGN-70	Immunology/Inflammation related
	Vorsetuzumab (Anti-Human CD70 Recombinant Antibody) is a monoclonal antibody targeting the CD70 antibody. Vorsetuzumab has anticancer activity and can enhance the macrophage-associated phagocytosis of kidney cancer cells...		Immunology/Inflammation related
T76743	Emibetuzumab	LY2875358	c-Met/HGFR
	Emibetuzumab is a potent humanized bivalent MET antibody (IgG4 type). Emibetuzumab has antitumor activity, inhibition of HGF-dependent and independent MET pathway activation and tumor growth, and can be used to study adv...		c-Met/HGFR
T76720	Farletuzumab	MORAb-003	Antifolate
	Farletuzumab (MORAb-003) is a potent inhibitor of folate receptor-α (FRα). Farletuzumab is a humanized monoclonal antibody with a high affinity for FRα. Farletuzumab inhibits the growth of cells that overexpress FRα. Far...		Antifolate
T76692	Mosunetuzumab	BTCT-4465A	Others
	Mosunetuzumab (BCT-4465A) is a humanized antibody based on immunoglobulin G1 that targets CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used to stu...		Others
T19761	Sulfometuron-methyl	DXP 5648,DXP-5648,DXP5648	Antibacterial
	Sulfometuron-methyl (DXP-5648) is a herbicide and also is an active antibacterial agent. It is an effective inhibitor of acetolactate synthase II and thus shows antibacterial properties.		Antibacterial