Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Diminazene is a trypanocidal agent.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | In stock | $ 42.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 46.00 |
Description | Diminazene is a trypanocidal agent. |
In vitro | Administering 7 mg/kg, i.m. of Diminazene aceturate effectively clears parasites from the bloodstream of infected dogs. An initial treatment dose of 3.5 mg/kg of Diminazene aceturate significantly alleviates T. evansi infection in horses and mules, with parasites being eliminated from the peripheral blood within 1-7 days and 1-14 days, respectively. |
In vivo | Transport of [3H] diminazene is substantially inhibited by pentamidine and adenosine, with Ki values of 0.21 μM and 0.25 μM, respectively. Notably, [3H] diminazene accumulates in yeast cells expressing TbAT1 at a rate of 0.0083 pmol/10^7 cells/s when treated with 2.5 μM of the radioactive compound, and this accumulation is completely suppressed by 1 mM of unlabeled Diminazene Aceturate. |
Molecular Weight | 515.52 |
Formula | C22H29N9O6 |
CAS No. | 908-54-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 92 mg/mL (178.5 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 16 mg/mL (31 mM)
You can also refer to dose conversion for different animals. More
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Diminazene Aceturate 908-54-3 Microbiology/Virology Others Proteases/Proteasome Serine Protease Parasite Inhibitor Diminazene Angiotensin-converting Enzyme (ACE) Diminazene diaceturate inhibit inhibitor