ulcers — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4981	Anisotropine Methylbromide		Prostaglandin Receptor , AChR
	Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.		Prostaglandin Receptor , AChR
T1575	Nizatidine	Axid,Acinon,Zanizal	AChE , Histamine Receptor
	Nizatidine (Acinon) is a competitive and reversible histamine H2-receptor antagonist with antacid activity.		AChE , Histamine Receptor
T14975	CJ-42794	CJ-042794	Others
	CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4). It inhibits [3H]-PGE2 binding to the human EP4 receptor (a mean pKi: 8.5). CJ-42794 is a binding affinity that was at least 200-...		Others
T1756L	Ilaprazole	IY81149,IY 81149,IY-81149	Proton pump , TOPK
	Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that Ilaprazole significantly prevented the developm...		Proton pump , TOPK
T1756	Ilaprazole sodium	IY-81149 sodium	Proton pump , TOPK
	Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus...		Proton pump , TOPK
T0070	Pentoxifylline	Oxpentifylline,PTX,BL-191	HIV Protease , PDE , Adenosine Receptor , Autophagy
	Pentoxifylline (PTX) modulates immunologic activity by stimulating cytokine production. Pentoxifylline is a methylxanthine derivative that inhibits phosphodiesterase and affects blood rheology. It also inhibits platelet ...		HIV Protease , PDE , Adenosine Receptor , Autophagy
T14546	Bermoprofen	AD-1590,AJ-1590	Others
	Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory compound with anti-inflammatory and analgesic activity used in the study of gastric ulcers.		Others
T33584	Namirotene	CBS 211A,Cbs 211 A	Others
	Namirotene (CBS 211A) is a protein biosynthesis inhibitor, a synthetic retinoic acid analog that is used in the study of corneal diseases, corneal ulcers and dry eye syndrome.		Others
T25737	Linetastine	TMK 688,TMK-688,TMK688	Lipoxygenase , LTR , Histamine Receptor
	Linetastine (TMK-688) is a 5-lipoxygenase inhibitor (5-LOX) that inhibits leukotriene production and antagonizes the effects of histamine.Linetastine is used in studies of asthma, atherosclerosis, and peptic ulcers.		Lipoxygenase , LTR , Histamine Receptor
T68100	Mifentidine	DA 4577	Histamine Receptor
	Mifentidine (DA 4577) is an orally available H2 receptor antagonist for the study of gastric emptying and experimental gastric and duodenal ulcers.		Histamine Receptor
T28136	NC-1300-B	NC1300B,NC 1300 B	ATPase
	NC-1300-B inhibits H(+)-K(+)-ATPase and is used in the study of gastric ulcers.		ATPase
T22267	Cetalkonium chloride	Benzylcetyldimethylammonium chloride hydrate	Antibacterial
	Cetalkonium chloride(Benzylcetyldimethylammonium chloride hydrate) is an ammonium preservative with anti-inflammatory activity that can be used in the study of aphthous ulcers.		Antibacterial
T68122	Oxmetidine	SKF 92994,Oxmetidina,Oxmetidinum	Histamine Receptor
	Oxmetidine (SKF 92994) is a novel H2 receptor antagonist that is cytotoxic. Oxmetidine inhibits transmembrane calcium flux in cardiac and vascular tissues and is used in the treatment of active duodenal ulcers.		Histamine Receptor
T1639	Amlexanox	CHX3673,Amoxanox,AA673	IL Receptor , FGFR , Others , IκB/IKK
	Amlexanox (AA673) is an anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexan...		IL Receptor , FGFR , Others , IκB/IKK
T15687	Thioflosulide	L-745337	COX
	Thioflosulide (L-745337) is a selective and potent COX2 inhibitor (IC50: 2.3 nM) with anti-inflammatory activity for the study of gastric ulcers.		COX
T23667	AGN-201904	AGN201904,AGN 201904	ATPase
	AGN-201904 is a proton pump inhibitor, an omeprazole prodrug, which delays aging and may be used for the prevention and treatment of peptic ulcers.		ATPase
T7099	Gefarnate		Others
	Gefarnate is a synthetic compound used for the treatment of gastric ulcers,and also used in the treatment of dry eye syndrome.		Others
T19826	Rabeprazole	LY307640	Potassium Channel , STAT
	Rabeprazole (LY307640) is an H+/K+-ATPase inhibitor that inhibits cell proliferation in gastric epithelial cells by targeting STAT3-mediated glycolysis and can be used in the study of gastric ulcers.		Potassium Channel , STAT
T33846	Oxyphenonium bromide	Spasmophen,Oxifenon,Oxyfenon,Atrenyl,Oxyphenon	Others
	Oxyphenonium bromide (Oxyfenon) shows anticholinergic activity and can be used for research on the treatment of gastric and duodenal ulcers and for the relief of visceral spasms.		Others
T8679	Epidermal Growth Factor		EGFR
	Epidermal Growth Factor binds to epidermal growth factor receptor (EGFR) and stimulates cell growth and proliferation. It is approved for the treatment of diabetic foot ulcers.		EGFR