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Search Results for " pulmonary "

20

Compounds

Cat No. Product Name Synonyms Targets
T1532 Pidotimod Others , Antibacterial
Pidotimod is a synthetic dipeptide with immunomodulatory properties.
T5036 Cangrelor tetrasodium GPR , P2Y Receptor
Cangrelor tetrasodium is a reversible and selective antagonist of platelet P2Y12, with prompt and potent antiplatelet effects.
T9592 OATD-01 Others
OATD-01 is a highly active inhibitor of both Chitotriosidase (CHIT1) and acidic mammalian chitinase (AMCase).
T12268 NTP42 Prostaglandin Receptor , PPAR
NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)
T6792 BQ-123 BQ123 Endothelin Receptor
BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.
T9699 TAK-615 LPA Receptor
TAK-615 is commonly used to study pulmonary fibrosis and is a negative allosteric modulator of LPA1 receptors.
T6054 GSK256066 PDE
GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380, 000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.Phase 2.
T9688 CC-90001 JNK
CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over JNK2.
T8313 HCH6-1 Others
HCH6-1 is a competitive Formyl peptide receptor 1 (FPR1) antagonist.
T1841 UNC0379 Histone Methyltransferase
UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.
T11339 Furegrelate sodium U-63557A PPAR
Furegrelate sodium (U-63557A) is a selective thromboxane synthase inhibitor with oral activity. Furegrelate sodium(U-63557A) inhibits thromboxane A2 (TXA2) synthase in human platelet microsomes with an IC50 of 15 nM.
T0120 Voriconazole UK-109496 Antifection , Antifungal
Voriconazole (UK-109496) is a triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-450 CYP3A.
T21712 BAY 41-8543 Others , Guanylate cyclase
BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).
TN1355 Acanthoside B Immunology/Inflammation related
Acanthoside B is a lignan with anti-inflammatory and anti-amnesic effects. Acanthoside B can be used for studies about Alzheimer's disease and lung inflammation.
T30258 AZD-4818 CCR1 antagonist CCR
AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.
T8900 Seralutinib GB002 PDGFR
Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.
T23322 SB 452533 TRP/TRPV Channel
SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).
T4503 Talniflumate Somalgen Chloride channel , COX , N-Acetylglucosaminyltransferase , Anion Exchanger
Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition o...
T5758 Sphondin COX , Prostaglandin Receptor
Sphondin has anticonvulsant, anti-inflammatory, and anti-proliferative activities, it possessed an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells.
T22358 Etalocib LY293111,VML295 Apoptosis , Leukotriene Receptor , LTR
Etalocib (LY293111) is a novel diaryl ether carboxylic acid derivative, is a selective and potent inhibitor of the lipoxygenase pathway either via antagonism of the leukotriene B4 (LTB4) receptor or directly through 5'-l...
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