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Etalocib

Catalog No. T22358 CAS 161172-51-6

Synonyms: LY293111, VML295

Etalocib is a novel diaryl ether carboxylic acid derivative, is a selective and potent inhibitor of the lipoxygenase pathway either via antagonism of the leukotriene B4 (LTB4) receptor or directly through 5'-lipoxygenase. It has antineoplastic activities.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Etalocib, CAS 161172-51-6

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	LY293111, VML295
Molecular Weight	544.61
Formula	C33H33FO6
CAS No.	161172-51-6

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 100 mg/mL (183.62 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. P Marder, et al. Blockade of Human Neutrophil Activation by 2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5- Hydroxyphenoxy]propoxy]phenoxy]benzoic Acid (LY293111), a Novel Leukotriene B4 Receptor Antagonist. Biochem Pharmacol. 1995 May 26;49(11):1683-90. 2. Wei-Gang Tong, et al. Leukotriene B4 Receptor Antagonist LY293111 Inhibits Proliferation and Induces Apoptosis in Human Pancreatic Cancer Cells. Clin Cancer Res. 2002 Oct;8(10):3232-42.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Immunology/Inflammation Compound Library Drug Repurposing Compound Library Anti-Cancer Active Compound Library Apoptosis Compound Library Anti-Cancer Drug Library Anti-Cancer Clinical Compound Library Bioactive Compound Library Clinical Compound Library

Related Products

Related compounds with same targets

(S)-(−)-Perillyl alcohol CPI-360 Diclofenac Potassium PF-543 GSK1904529A Ezatiostat LYN-1604 Curzerene

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Etalocib 161172-51-6 G蛋白偶联受体凋亡免疫与炎症 Apoptosis Leukotriene Receptor LTR antiinflammatory LY 293111 VML-295 VML 295 inhibit VML295 LY-293111 Pulmonary Inhibitor asthma bronchiectasis LY293111 inhibitor

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