Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 31.00 | |
2 mg | In stock | $ 44.00 | |
5 mg | In stock | $ 70.00 | |
10 mg | In stock | $ 98.00 | |
25 mg | In stock | $ 192.00 | |
50 mg | In stock | $ 316.00 | |
100 mg | In stock | $ 473.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 77.00 |
Description | Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome. |
Synonyms | Somalgen |
Molecular Weight | 414.33 |
Formula | C21H13F3N2O4 |
CAS No. | 66898-62-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL
You can also refer to dose conversion for different animals. More
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Talniflumate 66898-62-2 Immunology/Inflammation Membrane transporter/Ion channel Metabolism Neuroscience Chloride channel Anion Exchanger N-Acetylglucosaminyltransferase COX inhibit asthma cystic fibrosis Inhibitor Somalgen pulmonary obstructive Chloride Channel anti-inflammatory BA 7602-06 COPD Cl? Channels chronic ulcerogenic Intestinal disease analgesic inhibitor