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GSK256066

Catalog No. T6054    CAS 801312-28-7   

GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380,000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.Phase 2.

Pack Size Availability Price/USD Quantity
1 mg Inquiry 50.00
2 mg Inquiry 89.00
5 mg Inquiry 141.00
10 mg Inquiry 269.00
25 mg Inquiry 443.00
50 mg Inquiry 745.00
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Biological Activity:

Product Description:

GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380,000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.Phase 2.

Receptor:

PDE4B;

Chemical Information:
Molecular Weight 518.58
Formula C27H26N4O5S
CAS Number 801312-28-7
Solubility

DMSO: 9.6 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage store at -80°C
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Reference
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