forms — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6532	Hesperadin		Influenza Virus , Parasite , Aurora Kinase , Autophagy
	Hesperadin(IC50=250 nM) effectively inhibits Aurora B. It potently reduces the activity of AMPK, MAPKAP-K1, MKK1, Lck, CHK1 and PHK, but it could not inhibit MKK1 activity in vivo.		Influenza Virus , Parasite , Aurora Kinase , Autophagy
T14511	BAY1082439		Apoptosis , PI3K
	BAY1082439, an orally bioavailable, selective inhibitor of PI3Kα/β/δ, demonstrates high efficacy in inhibiting the growth of Pten-null prostate cancer [1][2]. Additionally, BAY1082439 is effective against mutated forms o...		Apoptosis , PI3K
T9304	(S)-Sunvozertinib	N-[5-[[4-[5-Chloro-4-fluoro-2-(2-hydroxypropan-2-yl)anilino]pyrimidin-2-yl]amino]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide,DZD9008	EGFR , HER
	(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.		EGFR , HER
T3901	Solasonine		Others
	Solasonine exerts leishmanicidal activity against promastigote forms of L. amazonensis.		Others
T8652	CASP3 Activator 1541		Caspase
	CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.		Caspase
T14766	BPH-715		Others , Parasite
	BPH-715 inhibits the liver-stage growth of P. falciparum with an IC50 of 10 μM for P. falciparum exoerythrocytic forms in HepG2 cells.		Others , Parasite
T3579	PLX8394		Raf
	PLX8394 is an orally active inhibitor of serine/threonine-protein kinase B-Raf (BRAF) protein. PLX8394 can selectively bind to and inhibit the activity of both wild-type and mutated forms of BRAF, then inhibit the prolif...		Raf
T7970	7-Ethoxycoumarin		Others
	7-Ethoxycoumarin, a typical human P450 substrate, is catalyzed by both wild-type and mutant forms of CYP102A1.		Others
T5S1550	Cinnamyl alcohol	Cinnamic Alcohol,Styryl Carbinol	PPAR
	Cinnamyl alcohol (Styryl Carbinol) readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.		PPAR
T0707L	Cyclophosphamide		DNA Alkylator/Crosslinker , DNA , MRP
	Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.		DNA Alkylator/Crosslinker , DNA , MRP
T20736	Cryptating agent 222	Cryptate 222,NSC 264495,NSC-264495,NSC264495	Others
	Cryptating agent 222 (NSC-264495) is a cryptand used with potassium mirror to reduce a hindered distannene to a crystalline radical anion and forms ligands with metal cations.		Others
T18595	Dasatinib carbaldehyde	PROTAC ABL binding moiety 4,BMS-354825 carbaldehyde	Others , Ligands for Target Protein for PROTAC
	Dasatinib carbaldehyde (PROTAC ABL binding moiety 4) is based on Dasatinib which is an ABL inhibitor, binds to the IAP ligand via a linker, and forms SNIPER [1].		Others , Ligands for Target Protein for PROTAC
T2346	Enasidenib	AG-221	Dehydrogenase , Isocitrate Dehydrogenase (IDH)
	Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potential antineoplastic activity.		Dehydrogenase , Isocitrate Dehydrogenase (IDH)
T13584	BMVC-8C3O		DNA/RNA Synthesis
	BMVC-8C3O, a DNA G-quadruplex (G4) ligand, induces the topological conversion from non-parallel to parallel forms in human telomeric DNA G4s.		DNA/RNA Synthesis
T5885	N-Acetyl-D-galactosamine	GalNAc	Others
	N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans.		Others
T6918	Olmutinib	HM61713, BI 1482694,BI 1482694,HM61713	EGFR , BTK
	Olmutinib (HM61713, BI 1482694) is an orally available small molecule, a mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Olmutinib binds to and inhibits mutan...		EGFR , BTK
T3024	Avitinib	AC0010	EGFR , JAK , BTK
	Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor, with potential antineoplastic activity. Upon oral administrat...		EGFR , JAK , BTK
T0951	Hydroxychloroquine sulfate	Acidum iopanoicum,HCQ sulfate	DNA , SARS-CoV , TLR , Parasite , Autophagy
	Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in ...		DNA , SARS-CoV , TLR , Parasite , Autophagy
T2S0961	Chalcone	benzylideneacetophenone,phenyl styryl ketone,Cinnamophenone,benzalacetophenone,β-phenylacrylophenone	EGFR , Antibacterial
	Chalcone (Cinnamophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones.		EGFR , Antibacterial
T9473	4SC-203		FLT
	4SC-203 is a multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEG...		FLT