decrease — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6991	Nitroprusside disodium dihydrate	Sodium Nitroferricyanide(III) Dihydrate,Sodium Nitroprusside Dihydrate	Guanylate cyclase , Autophagy
	Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood.		Guanylate cyclase , Autophagy
TN1698	Glucotropaeolin potassium	Glucotropaeolin,Benzylglucosinolate potassium,Glucotropaeolin Potassium Salt	Others
	Glucotropaeolin potassium (Benzylglucosinolate potassium) is found in cruciferous vegetables and moderately decrease spontaneous DNA damage in animals.		Others
T7617	Neurotensin(8-13)	Neurotensin(8-13)(3TFA)	Neurotensin Receptor
	Neurotensin(8-13) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.		Neurotensin Receptor
TN1589	Dihydrowithaferin A		AChE
	Dihydrowithaferin A is a withanolide isolated from Withania somnifera with activity against acetylcholinesterase (AChE). Dihydrowithaferin A in the diet may prevent or decrease the growth of tumors.		AChE
TN1916	Matairesinol		ATPase , p38 MAPK , ROS
	Matairesinol has radical and superoxide scavenging activities,; it also has anti-angiogenic activity by suppressing mROS signaling , can decrease hypoxia-inducible factor-1α± in hypoxic HeLa cells.		ATPase , p38 MAPK , ROS
T19552	RPH-2823		Others
	RPH-2823, a basic amphotericin analog, is diuretic, natriuretic, and potassium-preserving, inducing a dose-dependent decrease in SCC and an increase in trans-epithelial resistance.		Others
T15794	LUT014		Raf
	LUT014 is a B-Raf inhibitor (IC50: 11.7 nM) and developed to decrease dose-limiting acneiform lesions associated with EGFR Inhibitors treatment.		Raf
T0839	Ketoprofen	RP-19583	Apoptosis , COX , MRP
	Ketoprofen (RP-19583) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenas...		Apoptosis , COX , MRP
T5S0229	Isosakuranetin	4'-Methylnaringenin	Others
	1. Isosakuranetin (4'-Methylnaringenin) has cytotoxic and fungicide properties. 2. Isosakuranetin produces significant decrease in blood pressure. 3. Isosakuranetin significantly reduces the sensitivity of mice to noxiou...		Others
TJS1382	Taraxerone		Dehydrogenase
	Taraxerone has allelopathic and antifungal effects.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration with the concentration dep...		Dehydrogenase
T1299	3-Pyridinemethanol	Nicotinyl alcohol,Roniacol	Others
	3-Pyridinemethanol (Roniacol) is an alcohol analog of NICOTINIC ACID which is a direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and threatened GANGRENE.		Others
T7617L	Neurotensin(8-13) 3TFA(60482-95-3(free base))		Neurotensin Receptor
	Neurotensin(8-13) 3TFA is Neurotensin (NT) fragment. Neurotensin(8-13) 3TFA results in a decrease in cell-surface NT1 receptors (NTR1) density.		Neurotensin Receptor
T28543	RK-9123016	RK9123016,RK 9123016	Sirtuin
	RK-9123016 is a SIRT2 inhibitor. RK-9123016 increases the acetylation level of eukaryotic translation initiation factor 5A (eIF5A), a physiological substrate of SIRT2, and reduces cell viability of human breast cancer ce...		Sirtuin
T67728	α-Glucosidase-IN-23		Glucosidase
	α-Glucosidase-IN-23 is an orally active α-Glucosidase inhibitor. α-Glucosidase-IN-23 can decrease blood glucose by α-glucosidase inhibition (IC50= 4.48 μM).		Glucosidase
T67778	DCeMM1		Molecular Glues
	dCeMM1 is a RBM39 glue degrader. dCeMM1 can re-direct the activity of the CRL4DCAF15 ligase. dCeMM1 can decrease the expression levels of RBM39 in WT KBM7 cells.		Molecular Glues
T21432	Molindone	(±)-Molindone,Moban,Molindonum,SPN-810M	Dopamine Receptor
	Molindone ((±)-Molindone) is a therapeutic antipsychotic used to treat schizophrenia by blocking the action of dopamine in the brain. molindone is often used in combination with serotonin in a dose-dependent manner to in...		Dopamine Receptor
TN1740	Homoeriodictyol		5-HT Receptor , transporter , Sodium Channel , Drug Metabolite
	Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can increase SGLT-1-mediated glucose uptake but decrease serotoni...
T3685	SR9009	Stenabolic,REV-ERB Agonist II	Autophagy
	SR9009 (Stenabolic), a REV-ERB agonist, increases the constitutive repression of genes regulated by REV-ERBα/ERBβ (IC50: 670/800 nM). Through activation of REV-ERB, SR9009 can decrease circadian locomotor activity during...		Autophagy
T3937	Methyl L-histidinate dihydrochloride	L-Histidine methyl ester dihydrochloride	HDAC
	The inhibitory effect of Methyl L-histidinate dihydrochloride (L-Histidine methyl ester dihydrochloride) on histidine decarboxylase in Sprague-Dawley rat stomach assessed as decrease in 14CO2 production with activty valu...		HDAC
T4S1518	Pseudoginsenoside RT1		Others
	Pseudoginsenoside RT1, isolated from the fruit of Randia siamensis, exhibits acute ichthyotoxic activity. Pseudoginsenoside RT1 can cause a decrease in blood pressure, an increase in heart rate and an increase in spontan...		Others