store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RPH-2823, a basic amphotericin analog, is diuretic, natriuretic, and potassium-preserving, inducing a dose-dependent decrease in SCC and an increase in trans-epithelial resistance.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 6-8 weeks | $ 293.00 | |
5 mg | 6-8 weeks | $ 736.00 | |
10 mg | 6-8 weeks | $ 987.00 | |
25 mg | 6-8 weeks | $ 1,490.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | RPH-2823, a basic amphotericin analog, is diuretic, natriuretic, and potassium-preserving, inducing a dose-dependent decrease in SCC and an increase in trans-epithelial resistance. |
In vitro | Interacting with the Na+ channel or a regulator site within the apical membrane, RPH-2823 influences transepithelial Na+ transport[2]. |
In vivo | Avoiding the kaliuresis of 25 mumol/kg furosemide in male Wistar rats, RPH 2823 (2.5 mumol/kg) demonstrates its efficacy. RPH 2823 (1 mg/kg and 5 mg/kg, i.v.) exhibits a terminal elimination half-life of 3 h, with approximately 47% of the administered dose being excreted unchanged in the urine[1]. |
Molecular Weight | 370.41 |
Formula | C17H22N8O2 |
CAS No. | 96558-24-6 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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RPH-2823 96558-24-6 Others RPH 2823 RPH2823 inhibitor inhibit