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Dihydrowithaferin A

Catalog No. TN1589 CAS 5589-41-3

Dihydrowithaferin A is a withanolide isolated from Withania somnifera with activity against acetylcholinesterase (AChE). Dihydrowithaferin A in the diet may prevent or decrease the growth of tumors.

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Dihydrowithaferin A, CAS 5589-41-3

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Dihydrowithaferin A is a withanolide isolated from Withania somnifera with activity against acetylcholinesterase (AChE). Dihydrowithaferin A in the diet may prevent or decrease the growth of tumors.
In vitro	Withaferin A and its derivatives exhibited inhibitory concentrations (50%) ranging from 0.24 to 11.6 microg/mL[1].

Molecular Weight	472.61
Formula	C28H40O6
CAS No.	5589-41-3

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 45 mg/mL (95.22 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Jayaprakasam B, et al. Growth inhibition of human tumor cell lines by withanolides from Withania somnifera leaves. Life Sci. 2003 Nov 21;74(1):125-32. 2. Choudhary MI, et al. Cholinesterase inhibiting withanolides from Withania somnifera. Chem Pharm Bull (Tokyo). 2004 Nov;52(11):1358-61.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Dihydrowithaferin A 5589-41-3 Neuroscience AChE 2,3-Dihydrowithaferin A inhibit Inhibitor Cholinesterase (ChE) inhibitor

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