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Search Results for " anti-atherosclerotic "

20

Compounds

Cat No. Product Name Synonyms Targets
T23550 YM-750 YM 750 Acyltransferase
YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholest...
T1781 GW9508 GW 9508 GPR , Potassium Channel
GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
T0686 Orlistat Ro-18-0647,Tetrahydrolipstatin Apoptosis , Others , Fatty Acid Synthase
Orlistat (Tetrahydrolipstatin) is an Intestinal Lipase Inhibitor. The mechanism of action of orlistat is as a Lipase Inhibitor.
T10063 LDL-IN-3 Antioxidant
LDL-IN-3 shows anti-atherosclerotic and antioxidant activities.
T2901 Daidzin NPI-031D,Daidzein 7-O-glucoside,Daidzoside,Daidzein 7-glucoside Dehydrogenase , Reverse Transcriptase , Mitochondrial Metabolism
Daidzin (Daidzoside) is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.
T12981 SP-8356 Autophagy
SP-8356 is a potent, orally active inhibitor of cluster of differentiation 147 (CD147),and is an anti-inflammatory synthetic verbenone derivative, with anti-atherosclerotic effects.
T10584 Bovinic acid (9Z,11E)-Octadecadienoic acid,Rumenic acid Endogenous Metabolite
Bovinic acid ((9Z,11E)-Octadecadienoic acid) is a conjugated linoleic acid with anticancer and anti-atherosclerotic activity and can be used to study coronary heart disease and obesity in the elderly.
T1082 Benzyl isothiocyanate Benzoylthiocarbimide,Isothiocyanic Acid Benzoyl Ester Apoptosis , Antibacterial , Antibiotic
Benzyl isothiocyanate (Benzoylthiocarbimide) (BITC) is an isothiocyanate originally found in cruciferous vegetables. It shows immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiog...
T8189 Dihydroberberine Potassium Channel , HSP , HER
Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interacti...
T3S0364 L-Arginine L-Arg,(S)-(+)-Arginine IL Receptor , Endogenous Metabolite , NO Synthase
1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate...
TN1711 Gossypetin Antioxidant , p38 MAPK , MAPK , Antibacterial
Gossypetin, a hexahydroxylated flavonoid extractable from Rhodiola rosea Linn. is a potent MKK3 and MKK6 inhibitor that strongly attenuates the MKK3/6-p38 signaling pathway.Gossypetin exhibits antimutagenic, antiatherosc...
T12848 SB-657510 Others , Neurotensin Receptor
SB-657510 is a urotensin II (UII) receptor (UT) antagonist. The Ki values of UT for human, monkey, cat, rat and mouse were 61, 17, 30, 65 and 56 nM, respectively. SB-657510 plays an anti-inflammatory role by inhibiting U...
T24592 Pamaqueside CP-148,623,CP 148623,L 165313,L165313,L-165313
Pamaqueside is an anti-atherosclerotic agent.
T28290 Pactimibe CS 505,CS-505,CS505,Pactimibe free base
Pactimibe is a ACAT inhibitor. It has anti-atherosclerotic activity.
T30917 CI 924 EINECS 279-174-7,CI-924,CI924
CI 924 is a lipid-lowering drug. CI 924 increased anti-atherosclerotic HDL and decreased VLDL at 600 mg/day.
T32028 GYKI-14451 sulfate GYKI14451,GYKI14,451,GYKI-14451,GYKI 14451,GYKI 14,451,GYKI-14,451
GYKI-14451 (LY-178207) is a synthetic thrombin tripeptide inhibitor with anti-atherosclerotic activity.
TN2075 Pimaric acid MMP , p38 MAPK , NF-κB
Pimaric acid has potent anti-atherosclerotic activity with inhibitory action on matrix metalloproteinase-9 production and cell migration in TNF-α±-induced human aortic smooth muscle cells.
T7072 Pitavastatin
Pitavastatin (NK-104) is a potent inhibitor of hydroxymethylglutaryl-CoA (HMG-CoA) reductase, effectively inhibiting cholesterol synthesis from acetic acid in HepG2 cells with an IC 50 of 5.8 nM. It also acts as an effic...
T35577 Phosphatidylserines (bovine)
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on th...
T35578 Phosphatidylserines (sodium salt) Phosphatidylserines (sodium salt),L-α-Phosphatidylserine
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on th...

Compounds

YM-750
T23550
Synonym: YM 750
Target: Acyltransferase
GW9508
T1781
Synonym: GW 9508
Target: GPR, Potassium Channel
Orlistat
T0686
Synonym: Ro-18-0647,Tetrahydrolipstatin
Target: Apoptosis, Others, Fatty Acid Synthase
LDL-IN-3
T10063
Synonym:
Target: Antioxidant
Daidzin
T2901
Synonym: NPI-031D,Daidzein 7-O-glucoside,Daidzoside,Daidzein 7-glucoside
Target: Dehydrogenase, Reverse Transcriptase, Mitochondrial Metabolism
SP-8356
T12981
Synonym:
Target: Autophagy
Bovinic acid
T10584
Synonym: (9Z,11E)-Octadecadienoic acid,Rumenic acid
Target: Endogenous Metabolite
Benzyl isothiocyanate
T1082
Synonym: Benzoylthiocarbimide,Isothiocyanic Acid Benzoyl Ester
Target: Apoptosis, Antibacterial, Antibiotic
Dihydroberberine
T8189
Synonym:
Target: Potassium Channel, HSP, HER
L-Arginine
T3S0364
Synonym: L-Arg,(S)-(+)-Arginine
Target: IL Receptor, Endogenous Metabolite, NO Synthase
Gossypetin
TN1711
Synonym:
Target: Antioxidant, p38 MAPK, MAPK, Antibacterial
SB-657510
T12848
Synonym:
Target: Others, Neurotensin Receptor
Pamaqueside
T24592
Synonym: CP-148,623,CP 148623,L 165313,L165313,L-165313
Target:
Pactimibe
T28290
Synonym: CS 505,CS-505,CS505,Pactimibe free base
Target:
CI 924
T30917
Synonym: EINECS 279-174-7,CI-924,CI924
Target:
GYKI-14451 sulfate
T32028
Synonym: GYKI14451,GYKI14,451,GYKI-14451,GYKI 14451,GYKI 14,451,GYKI-14,451
Target:
Pimaric acid
TN2075
Synonym:
Target: MMP, p38 MAPK, NF-κB
Pitavastatin
T7072
Synonym:
Target:
Phosphatidylserines (bovine)
T35577
Synonym:
Target:
Phosphatidylserines (sodium salt)
T35578
Synonym: Phosphatidylserines (sodium salt),L-α-Phosphatidylserine
Target:
TargetMol