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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T23550 | YM-750 | YM 750 | Acyltransferase |
YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholest... | |||
T1781 | GW9508 | GW 9508 | GPR , Potassium Channel |
GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner. | |||
T0686 | Orlistat | Ro-18-0647,Tetrahydrolipstatin | Apoptosis , Others , Fatty Acid Synthase |
Orlistat (Tetrahydrolipstatin) is an Intestinal Lipase Inhibitor. The mechanism of action of orlistat is as a Lipase Inhibitor. | |||
T10063 | LDL-IN-3 | Antioxidant | |
LDL-IN-3 shows anti-atherosclerotic and antioxidant activities. | |||
T2901 | Daidzin | NPI-031D,Daidzein 7-O-glucoside,Daidzoside,Daidzein 7-glucoside | Dehydrogenase , Reverse Transcriptase , Mitochondrial Metabolism |
Daidzin (Daidzoside) is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities. | |||
T12981 | SP-8356 | Autophagy | |
SP-8356 is a potent, orally active inhibitor of cluster of differentiation 147 (CD147),and is an anti-inflammatory synthetic verbenone derivative, with anti-atherosclerotic effects. | |||
T10584 | Bovinic acid | (9Z,11E)-Octadecadienoic acid,Rumenic acid | Endogenous Metabolite |
Bovinic acid ((9Z,11E)-Octadecadienoic acid) is a conjugated linoleic acid with anticancer and anti-atherosclerotic activity and can be used to study coronary heart disease and obesity in the elderly. | |||
T1082 | Benzyl isothiocyanate | Benzoylthiocarbimide,Isothiocyanic Acid Benzoyl Ester | Apoptosis , Antibacterial , Antibiotic |
Benzyl isothiocyanate (Benzoylthiocarbimide) (BITC) is an isothiocyanate originally found in cruciferous vegetables. It shows immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiog... | |||
T8189 | Dihydroberberine | Potassium Channel , HSP , HER | |
Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interacti... | |||
T3S0364 | L-Arginine | L-Arg,(S)-(+)-Arginine | IL Receptor , Endogenous Metabolite , NO Synthase |
1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate... | |||
TN1711 | Gossypetin | Antioxidant , p38 MAPK , MAPK , Antibacterial | |
Gossypetin, a hexahydroxylated flavonoid extractable from Rhodiola rosea Linn. is a potent MKK3 and MKK6 inhibitor that strongly attenuates the MKK3/6-p38 signaling pathway.Gossypetin exhibits antimutagenic, antiatherosc... | |||
T12848 | SB-657510 | Others , Neurotensin Receptor | |
SB-657510 is a urotensin II (UII) receptor (UT) antagonist. The Ki values of UT for human, monkey, cat, rat and mouse were 61, 17, 30, 65 and 56 nM, respectively. SB-657510 plays an anti-inflammatory role by inhibiting U... | |||
T24592 | Pamaqueside | CP-148,623,CP 148623,L 165313,L165313,L-165313 | |
Pamaqueside is an anti-atherosclerotic agent. | |||
T28290 | Pactimibe | CS 505,CS-505,CS505,Pactimibe free base | |
Pactimibe is a ACAT inhibitor. It has anti-atherosclerotic activity. | |||
T30917 | CI 924 | EINECS 279-174-7,CI-924,CI924 | |
CI 924 is a lipid-lowering drug. CI 924 increased anti-atherosclerotic HDL and decreased VLDL at 600 mg/day. | |||
T32028 | GYKI-14451 sulfate | GYKI14451,GYKI14,451,GYKI-14451,GYKI 14451,GYKI 14,451,GYKI-14,451 | |
GYKI-14451 (LY-178207) is a synthetic thrombin tripeptide inhibitor with anti-atherosclerotic activity. | |||
TN2075 | Pimaric acid | MMP , p38 MAPK , NF-κB | |
Pimaric acid has potent anti-atherosclerotic activity with inhibitory action on matrix metalloproteinase-9 production and cell migration in TNF-α±-induced human aortic smooth muscle cells. | |||
T7072 | Pitavastatin | ||
Pitavastatin (NK-104) is a potent inhibitor of hydroxymethylglutaryl-CoA (HMG-CoA) reductase, effectively inhibiting cholesterol synthesis from acetic acid in HepG2 cells with an IC 50 of 5.8 nM. It also acts as an effic... | |||
T35577 | Phosphatidylserines (bovine) | ||
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on th... | |||
T35578 | Phosphatidylserines (sodium salt) | Phosphatidylserines (sodium salt),L-α-Phosphatidylserine | |
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on th... |